Knockdown of USP39 induces cell cycle arrest and apoptosis in melanoma

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Metabolic control of methylation and acetylation

(2016) Xiaoyang Su et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Advances in targeted therapy for unresectable melanoma: New drugs and combinations

(2015) Mengze Hao et al.   CANCER LETTERS

Reduced USP39 expression inhibits malignant proliferation of medullary thyroid carcinoma in vitro

(2015) Yong An et al.   World Journal of Surgical Oncology

The MAPK pathway across different malignancies: A new perspective

(2014) Mauricio Burotto et al.   CANCER

RETRACTED ARTICLE: Targeted immune therapy of ovarian cancer

(2014) Keith L. Knutson et al.   CANCER AND METASTASIS REVIEWS

Oncogenes in melanoma: An update

(2014) Manfred Kunz   EUROPEAN JOURNAL OF CELL BIOLOGY

Pre-mRNA splicing in cancer: the relevance in oncogenesis, treatment and drug resistance

(2014) Anna Wojtuszkiewicz et al.   Expert Opinion on Drug Metabolism & Toxicology

An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth

(2014) A. S. Adler et al.   GENES & DEVELOPMENT

Safety and efficacy of vemurafenib in BRAFV600E and BRAFV600K mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label study

(2014) Grant A McArthur et al.   LANCET ONCOLOGY

Emerging Functions of SRSF1, Splicing Factor and Oncoprotein, in RNA Metabolism and Cancer

(2014) S. Das et al.   MOLECULAR CANCER RESEARCH

Targeting RAS–ERK signalling in cancer: promises and challenges

(2014) Ahmed A. Samatar et al.   NATURE REVIEWS DRUG DISCOVERY

The crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing

(2014) H. Hadjivassiliou et al.   RNA

Targeting the Deregulated Spliceosome Core Machinery in Cancer Cells Triggers mTOR Blockade and Autophagy

(2013) V. Quidville et al.   CANCER RESEARCH

BRAF in Melanoma: Current Strategies and Future Directions

(2013) A. K. S. Salama et al.   CLINICAL CANCER RESEARCH

Cutaneous melanoma

(2013) Alexander MM Eggermont et al.   LANCET

Tumor adaptation and resistance to RAF inhibitors

(2013) Piro Lito et al.   NATURE MEDICINE

Overexpression of TROP2 Predicts Poor Prognosis of Patients with Cervical Cancer and Promotes the Proliferation and Invasion of Cervical Cancer Cells by Regulating ERK Signaling Pathway

(2013) Ting Liu et al.   PLoS One

Functional roles of protein splicing factors

(2012) Hsin‑Chou Chen et al.   BIOSCIENCE REPORTS

The spliceosome as a target of novel antitumour drugs

(2012) Sophie Bonnal et al.   NATURE REVIEWS DRUG DISCOVERY

Survival in BRAF V600–Mutant Advanced Melanoma Treated with Vemurafenib

(2012) Jeffrey A. Sosman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness

(2011) D. Rossi et al.   BLOOD

Usp39 is essential for mitotic spindle checkpoint integrity and controls mRNA-levels of Aurora B

(2011) Renske J. van Leuken et al.   CELL CYCLE

Frequent pathway mutations of splicing machinery in myelodysplasia

(2011) Kenichi Yoshida et al.   NATURE

Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes

(2011) Timothy A Graubert et al.   NATURE GENETICS

SF3B1and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia

(2011) Lili Wang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Deubiquitinases in cancer: new functions and therapeutic options

(2011) J M Fraile et al.   ONCOGENE

Zebrafish usp39 Mutation Leads to rb1 mRNA Splicing Defect and Pituitary Lineage Expansion

(2011) Yesenia Ríos et al.   PLoS Genetics

CDK Inhibitors: Cell Cycle Regulators and Beyond

(2008) Arnaud Besson et al.   DEVELOPMENTAL CELL

Aberrant RNA splicing and its functional consequences in cancer cells

(2008) J. D. Fackenthal et al.   Disease Models & Mechanisms