Arsenite inhibits the function of CD133+ CD13+ liver cancer stem cells by reducing PML and Oct4 protein expression

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells

(2014) Mario L. Suvà et al.   CELL

The role of PML in hematopoietic and leukemic stem cell maintenance

(2014) Fumio Nakahara et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

All-trans retinoic acid and arsenic trioxide induce apoptosis and modulate intracellular concentrations of calcium in hepatocellular carcinoma cells

(2014) Jianfeng Wei et al.   JOURNAL OF CHEMOTHERAPY

SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma

(2014) Soufiane Boumahdi et al.   NATURE

Oct4 is a critical regulator of stemness in head and neck squamous carcinoma cells

(2014) B S Koo et al.   ONCOGENE

Reduced Oct4 Expression Directs a Robust Pluripotent State with Distinct Signaling Activity and Increased Enhancer Occupancy by Oct4 and Nanog

(2013) Violetta Karwacki-Neisius et al.   Cell Stem Cell

Cancer stem cells in the development of liver cancer

(2013) Taro Yamashita et al.   JOURNAL OF CLINICAL INVESTIGATION

CD133+EpCAM+ Phenotype Possesses More Characteristics of Tumor Initiating Cells in Hepatocellular Carcinoma Huh7 Cells

(2012) Yi Chen et al.   International Journal of Biological Sciences

Defining the mode of tumour growth by clonal analysis

(2012) Gregory Driessens et al.   NATURE

A restricted cell population propagates glioblastoma growth after chemotherapy

(2012) Jian Chen et al.   NATURE

Lineage Tracing Reveals Lgr5+ Stem Cell Activity in Mouse Intestinal Adenomas

(2012) A. G. Schepers et al.   SCIENCE

Increased CD13 Expression Reduces Reactive Oxygen Species, Promoting Survival of Liver Cancer Stem Cells via an Epithelial–Mesenchymal Transition-like Phenomenon

(2011) Ho Min Kim et al.   ANNALS OF SURGICAL ONCOLOGY

Suppression of TG-interacting factor sensitizes arsenic trioxide-induced apoptosis in human hepatocellular carcinoma cells

(2011) Zi-Miao Liu et al.   BIOCHEMICAL JOURNAL

The role of PML in the control of apoptotic cell fate: a new key player at ER–mitochondria sites

(2011) P Pinton et al.   CELL DEATH AND DIFFERENTIATION

CD13: Waving the flag for a novel cancer stem cell target

(2011) Bruno Christ et al.   HEPATOLOGY

Promyelocytic Leukemia Protein in Retinoic Acid-Induced Chromatin Remodeling of Oct4 Gene Promoter

(2011) Ya-Shan Chuang et al.   STEM CELLS

PML/RARA Oxidation and Arsenic Binding Initiate the Antileukemia Response of As2O3

(2010) Marion Jeanne et al.   CANCER CELL

Pancreatic Cancer Cells Resistant to Chemoradiotherapy Rich in “Stem-Cell-Like” Tumor Cells

(2010) Zhiyong Du et al.   DIGESTIVE DISEASES AND SCIENCES

CD13 is a therapeutic target in human liver cancer stem cells

(2010) Naotsugu Haraguchi et al.   JOURNAL OF CLINICAL INVESTIGATION

Expression of CD133 confers malignant potential by regulating metalloproteinases in human hepatocellular carcinoma

(2010) Keisuke Kohga et al.   JOURNAL OF HEPATOLOGY

Arsenic Trioxide Controls the Fate of the PML-RAR  Oncoprotein by Directly Binding PML

(2010) X. W. Zhang et al.   SCIENCE

Phosphorylation of Sox2 Cooperates in Reprogramming to Pluripotent Stem Cells

(2010) Chul-Ho Jeong et al.   STEM CELLS

Cancer Statistics, 2009

(2009) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

PML targeting eradicates quiescent leukaemia-initiating cells

(2008) Keisuke Ito et al.   NATURE

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY