Using ToxCast to Explore Chemical Activities and Hazard Traits: A Case Study WithOrtho-Phthalates

Benzyl butyl phthalate induces migration, invasion, and angiogenesis of Huh7 hepatocellular carcinoma cells through nongenomic AhR/G-protein signaling

(2014) Cheng-Fang Tsai et al.   BMC CANCER

Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms

(2014) Nicole C Kleinstreuer et al.   NATURE BIOTECHNOLOGY

Perspectives on validation of high-throughput assays supporting 21st century toxicity testing

(2014) Richard Judson   ALTEX-Alternatives to Animal Experimentation

Prenatal exposure to phthalates is associated with decreased anogenital distance and penile size in male newborns

(2013) L. P. Bustamante-Montes et al.   Journal of Developmental Origins of Health and Disease

Relative sensitivity of developmental and immune parameters in juvenile versus adult male rats after exposure to di(2-ethylhexyl) phthalate

(2012) Elisa C.M. Tonk et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Predictive Model of Rat Reproductive Toxicity from ToxCast High Throughput Screening1

(2011) Matthew T Martin et al.   BIOLOGY OF REPRODUCTION

Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors

(2011) Ruili Huang et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Benzyl butyl phthalate induces necrosis by AhR mediation of CYP1B1 expression in human granulosa cells

(2011) Hung-Sheng Chen et al.   REPRODUCTIVE TOXICOLOGY

Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets

(2011) Thomas B. Knudsen et al.   TOXICOLOGY

Impact of Environmental Chemicals on Key Transcription Regulators and Correlation to Toxicity End Points within EPA’s ToxCast Program

(2010) Matthew T. Martin et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform

(2010) Sunita J. Shukla et al.   DRUG DISCOVERY TODAY

Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data

(2010) David M. Reif et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Dipentyl Phthalate Dosing during Sexual Differentiation Disrupts Fetal Testis Function and Postnatal Development of the Male Sprague-Dawley Rat with Greater Relative Potency than Other Phthalates

(2010) Bethany R. Hannas et al.   TOXICOLOGICAL SCIENCES

In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project

(2009) Richard S. Judson et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Differential developmental toxicities of di-n-hexyl phthalate and dicyclohexyl phthalate administered orally to rats

(2009) Anne-Marie Saillenfait et al.   JOURNAL OF APPLIED TOXICOLOGY

Diisobutyl phthalate impairs the androgen-dependent reproductive development of the male rat

(2008) Anne-Marie Saillenfait et al.   REPRODUCTIVE TOXICOLOGY