Preclinical Safety Evaluation in Rats of a Polymeric Matrix Containing an siRNA Drug Used as a Local and Prolonged Delivery System for Pancreatic Cancer Therapy

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Long-term Local and Systemic Safety of Poly(l-lactide-co-epsilon-caprolactone) after Subcutaneous and Intra-articular Implantation in Rats

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Nanoparticle-Delivered Transforming Growth Factor-β siRNA Enhances Vaccination against Advanced Melanoma by Modifying Tumor Microenvironment

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Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

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First-in-Human Phase I Study of the Liposomal RNA Interference Therapeutic Atu027 in Patients With Advanced Solid Tumors

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Histopathology of biodegradable polymers: challenges in interpretation and the use of a novel compact MRI for biocompatibility evaluation

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Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA

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RNAi Therapies: Drugging the Undruggable

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Interspecies Differences in Reaction to a Biodegradable Subcutaneous Tissue Filler

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A phase 1 study of the BCL2-targeted deoxyribonucleic acid inhibitor (DNAi) PNT2258 in patients with advanced solid tumors

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Challenging the future of siRNA therapeutics against cancer: the crucial role of nanotechnology

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Mutant KRAS is a druggable target for pancreatic cancer

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First-in-Humans Trial of an RNA Interference Therapeutic Targeting VEGF and KSP in Cancer Patients with Liver Involvement

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RNA-Based Therapeutics: Current Progress and Future Prospects

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Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

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Medical Device Regulations and Testing for Toxicologic Pathologists

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Polymer Implants for Intratumoral Drug Delivery and Cancer Therapy

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