The significance of autoantibodies to DFS70/LEDGFp75 in health and disease: integrating basic science with clinical understanding
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Title
The significance of autoantibodies to DFS70/LEDGFp75 in health and disease: integrating basic science with clinical understanding
Authors
Keywords
Antinuclear autoantibodies, Autoimmunity, DFS70/LEDGFp75, Inflammation, Stress
Journal
CLINICAL AND EXPERIMENTAL MEDICINE
Volume 16, Issue 3, Pages 273-293
Publisher
Springer Nature
Online
2015-06-18
DOI
10.1007/s10238-015-0367-0
References
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Note: Only part of the references are listed.- Host factors for retroviral integration site selection
- (2015) Zeger Debyser et al. TRENDS IN BIOCHEMICAL SCIENCES
- Transcriptional Regulation of Vascular Endothelial Growth Factor C by Oxidative and Thermal Stress Is Mediated by Lens Epithelium-Derived Growth Factor/p75
- (2015) Batya Cohen et al. NEOPLASIA
- Nuclear envelope localization of Ran-binding protein 2 and Ran-GTPase-activating protein 1 in psoriatic epidermal keratinocytes
- (2014) Kayo Yasuda et al. EXPERIMENTAL DERMATOLOGY
- Dynamics of the Ternary Complex Formed by c-Myc Interactor JPO2, Transcriptional Co-activator LEDGF/p75, and Chromatin
- (2014) Jelle Hendrix et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Natural IgM: Beneficial Autoantibodies for the Control of Inflammatory and Autoimmune Disease
- (2014) Caroline Grönwall et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Antinuclear Antibodies in Children
- (2014) M. MAHLER et al. JOURNAL OF RHEUMATOLOGY
- Amyopathic dermatomyositis developing rapidly progressive interstitial lung disease with elevation of anti-CADM-140/MDA5 autoantibodies
- (2014) Shinji Sato et al. Modern Rheumatology
- Psip1/Ledgf p75 restrainsHoxgene expression by recruiting both trithorax and polycomb group proteins
- (2014) Madapura M. Pradeepa et al. NUCLEIC ACIDS RESEARCH
- Anti-DFS70 Antibodies: A Useful Biomarker in a Pediatric Case With Suspected Autoimmune Disease
- (2014) Martina Fabris et al. PEDIATRICS
- Clinical and Serological Features of Patients Referred through a Rheumatology Triage System because of Positive Antinuclear Antibodies
- (2014) Christie Fitch-Rogalsky et al. PLoS One
- Structure and function of the nucleosome-binding PWWP domain
- (2014) Su Qin et al. TRENDS IN BIOCHEMICAL SCIENCES
- Oncogenic Human Papillomaviruses Activate the Tumor-Associated Lens Epithelial-Derived Growth Factor (LEDGF) Gene
- (2014) Jenny Leitz et al. PLoS Pathogens
- The Clinical Utility of a Positive Antinuclear Antibody Test Result
- (2013) Aryeh M. Abeles et al. AMERICAN JOURNAL OF MEDICINE
- Citrullination of autoantigens implicates NETosis in the induction of autoimmunity
- (2013) Nishant Dwivedi et al. ANNALS OF THE RHEUMATIC DISEASES
- Clinical Phenotypes of Patients with Anti-DFS70/LEDGF Antibodies in a Routine ANA Referral Cohort
- (2013) Makoto Miyara et al. Clinical & Developmental Immunology
- Epigenetic repression of LEDGF during UVB exposure by recruitment of SUV39H1 and HDAC1 to the Sp1-responsive elements within LEDGF promoter CpG island
- (2013) Biju Bhargavan et al. Epigenetics
- Biosynthesis, Characterization, and Efficacy in Retinal Degenerative Diseases of Lens Epithelium-derived Growth Factor Fragment (LEDGF1–326), a Novel Therapeutic Protein
- (2013) Rinku Baid et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- LEDGFp52 Controls Rat Retinal Ganglion Cell Neurite Growth in Culture and Regulates Specific Neuronal Growth-associated Genes and Protein Production
- (2013) HS Zhao et al. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- Low Prevalence of Anti-DFS70/LEDGF Antibodies in Patients with Dermatomyositis and Other Systemic Autoimmune Rheumatic Diseases
- (2013) Y. MURO et al. JOURNAL OF RHEUMATOLOGY
- Impairing MLL-fusion gene-mediated transformation by dissecting critical interactions with the lens epithelium-derived growth factor (LEDGF/p75)
- (2013) H Méreau et al. LEUKEMIA
- Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes
- (2013) Jocelyn O. Eidahl et al. NUCLEIC ACIDS RESEARCH
- Natural IgG Autoantibodies Are Abundant and Ubiquitous in Human Sera, and Their Number Is Influenced By Age, Gender, and Disease
- (2013) Eric P. Nagele et al. PLoS One
- TOX4 and NOVA1 Proteins Are Partners of the LEDGF PWWP Domain and Affect HIV-1 Replication
- (2013) Mehdi Morchikh et al. PLoS One
- Autoantibodies: Double Agents in Human Disease
- (2013) N. K. Acharya et al. Science Translational Medicine
- Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus
- (2012) Michelle Petri et al. ARTHRITIS AND RHEUMATISM
- The Clinical Significance of the Dense Fine Speckled Immunofluorescence Pattern on HEp-2 Cells for the Diagnosis of Systemic Autoimmune Diseases
- (2012) Michael Mahler et al. Clinical & Developmental Immunology
- Lens epithelium-derived growth factor deSumoylation by Sumo-specific protease-1 regulates its transcriptional activation of small heat shock protein and the cellular response
- (2012) Keiichi Ishihara et al. FEBS Journal
- Cohort profile of the CARTaGENE study: Quebec’s population-based biobank for public health and personalized genomics
- (2012) Philip Awadalla et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Anti-DFS70/LEDGF Antibodies Are More Prevalent in Healthy Individuals Compared to Patients with Systemic Autoimmune Rheumatic Diseases
- (2012) M. MAHLER et al. JOURNAL OF RHEUMATOLOGY
- The Stress Oncoprotein LEDGF/p75 Interacts with the Methyl CpG Binding Protein MeCP2 and Influences Its Transcriptional Activity
- (2012) L. S. Leoh et al. MOLECULAR CANCER RESEARCH
- LEDGF (p75) promotes DNA-end resection and homologous recombination
- (2012) Mads Daugaard et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Expression of the Stress Response Oncoprotein LEDGF/p75 in Human Cancer: A Study of 21 Tumor Types
- (2012) Anamika Basu et al. PLoS One
- Transcriptional Protein Sp1 Regulates LEDGF Transcription by Directly Interacting with Its Cis-Elements in GC-Rich Region of TATA-Less Gene Promoter
- (2012) Dhirendra P. Singh et al. PLoS One
- Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies
- (2012) Chih Liu et al. ARTHRITIS RESEARCH & THERAPY
- LEDGF gene silencing impairs the tumorigenicity of prostate cancer DU145 cells by abating the expression of Hsp27 and activation of the Akt/ERK signaling pathway
- (2012) B Bhargavan et al. Cell Death & Disease
- Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing
- (2012) Madapura M. Pradeepa et al. PLoS Genetics
- A Role for microRNA-155 Modulation in the Anti-HIV-1 Effects of Toll-Like Receptor 3 Stimulation in Macrophages
- (2012) Gokul Swaminathan et al. PLoS Pathogens
- Recognizing the dense fine speckled/lens epithelium-derived growth factor/p75 pattern on HEp-2 cells: Not an easy task! Comment on the article by Mariz et al
- (2011) Nicola Bizzaro et al. ARTHRITIS AND RHEUMATISM
- The dense fine speckled antinuclear antibody pattern in autoimmune rheumatic disease: Comment on the article by Mariz et al
- (2011) Wendy Y. Craig et al. ARTHRITIS AND RHEUMATISM
- IgE and IgG4autoantibodies against DFS70/LEDGF in atopic dermatitis
- (2011) Kanako Watanabe et al. AUTOIMMUNITY
- Importance of the dense fine speckled pattern on HEp-2 cells and anti-DFS70 antibodies for the diagnosis of systemic autoimmune diseases
- (2011) Michael Mahler et al. AUTOIMMUNITY REVIEWS
- Autoantibody signatures as biomarkers to distinguish prostate cancer from benign prostatic hyperplasia in patients with increased serum prostate specific antigen
- (2011) Dennis J. O'Rourke et al. CLINICA CHIMICA ACTA
- Cancer and systemic sclerosis
- (2011) Ami A. Shah et al. CURRENT OPINION IN RHEUMATOLOGY
- Role of the PWWP Domain of Lens Epithelium-derived Growth Factor (LEDGF)/p75 Cofactor in Lentiviral Integration Targeting
- (2011) Rik Gijsbers et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- LEDGF/DFS70 activates the MK2/IL6/STAT3 pathway in HaCaT
- (2011) Takuya Takeichi et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- LEDGF/p75 TATA-Less Promoter Is Driven by the Transcription Factor Sp1
- (2011) Sébastien Desfarges et al. JOURNAL OF MOLECULAR BIOLOGY
- A novel multiplex assay combining autoantibodies plus PSA has potential implications for classification of prostate cancer from non-malignant cases
- (2011) Chong Xie et al. Journal of Translational Medicine
- Nuclear protein LEDGF/p75 recognizes supercoiled DNA by a novel DNA-binding domain
- (2011) Kimiko M. Tsutsui et al. NUCLEIC ACIDS RESEARCH
- Fibromyalgia and chronic fatigue syndrome in children
- (2011) Yasuhiko Itoh et al. PEDIATRICS INTERNATIONAL
- Integration of Transcriptomics, Proteomics, and MicroRNA Analyses Reveals Novel MicroRNA Regulation of Targets in the Mammalian Inner Ear
- (2011) Tal Elkan-Miller et al. PLoS One
- LEDGF1-326 Decreases P23H and Wild Type Rhodopsin Aggregates and P23H Rhodopsin Mediated Cell Damage in Human Retinal Pigment Epithelial Cells
- (2011) Rinku Baid et al. PLoS One
- Antitumorigenic potential of STAT3 alternative splicing modulation
- (2011) F. Zammarchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathway specific gene expression profiling reveals oxidative stress genes potentially regulated by transcription co-activator LEDGF/p75 in prostate cancer cells
- (2011) Anamika Basu et al. PROSTATE
- Relevância clínica e frequência de padrões citoplasmático e pontilhado fino denso observados em FAN-HEp-2
- (2011) Andréia Martini Pazini et al. Revista Brasileira De Reumatologia
- The antinuclear antibody test: Last or lasting gasp?
- (2010) Marvin J. Fritzler ARTHRITIS AND RHEUMATISM
- Pattern on the antinuclear antibody-HEp-2 test is a critical parameter for discriminating antinuclear antibody-positive healthy individuals and patients with autoimmune rheumatic diseases
- (2010) Henrique A. Mariz et al. ARTHRITIS AND RHEUMATISM
- Autoimmunity and chronic inflammation — Two clearance-related steps in the etiopathogenesis of SLE
- (2010) Luis E. Muñoz et al. AUTOIMMUNITY REVIEWS
- Overexpression of LEDGF/DFS70 Induces IL-6 via p38 Activation in HaCaT Cells, Similar to that Seen in the Psoriatic Condition
- (2010) Takuya Takeichi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- SUMOylation of the Lens Epithelium-Derived Growth Factor/p75 Attenuates Its Transcriptional Activity on the Heat Shock Protein 27 Promoter
- (2010) Murilo T.D. Bueno et al. JOURNAL OF MOLECULAR BIOLOGY
- The transcriptional co-activator LEDGF/p75 displays a dynamic scan-and-lock mechanism for chromatin tethering
- (2010) Jelle Hendrix et al. NUCLEIC ACIDS RESEARCH
- High-resolution profiling of the LEDGF/p75 chromatin interaction in the ENCODE region
- (2010) Jan De Rijck et al. NUCLEIC ACIDS RESEARCH
- Autoantibodies to lens epithelium-derived growth factor/transcription co-activator P75 (LEDGF/P75) in children with chronic nonspecific complaints and with positive antinuclear antibodies
- (2009) Natsuko Kuwabara et al. AUTOIMMUNITY
- Gonadotropin-Regulated Lymphangiogenesis in Ovarian Cancer Is Mediated by LEDGF-Induced Expression of VEGF-C
- (2009) S. Sapoznik et al. CANCER RESEARCH
- Prevalence of Antinuclear Antibodies in 3 Groups of Healthy Individuals
- (2009) Guadalupe G. Marin et al. JCR-JOURNAL OF CLINICAL RHEUMATOLOGY
- Transcriptional Co-activator LEDGF Interacts with Cdc7-Activator of S-phase Kinase (ASK) and Stimulates Its Enzymatic Activity
- (2009) Siobhan Hughes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lens Epithelium-derived Growth Factor/p75 Interacts with the Transposase-derived DDE Domain of PogZ
- (2009) Koen Bartholomeeusen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Clinical Significance of Dense Fine Speckled Pattern in Anti-nuclear Antibody Test using Indirect Immunofluorescence Method
- (2009) So Young Kang et al. Korean Journal of Laboratory Medicine
- Docetaxel-induced prostate cancer cell death involves concomitant activation of caspase and lysosomal pathways and is attenuated by LEDGF/p75
- (2009) Melanie Mediavilla-Varela et al. Molecular Cancer
- Menin Critically Links MLL Proteins with LEDGF on Cancer-Associated Target Genes
- (2008) Akihiko Yokoyama et al. CANCER CELL
- Autoantibodies to tumor-associated antigens: reporters from the immune system
- (2008) Eng M. Tan et al. IMMUNOLOGICAL REVIEWS
- High concomitance of disease marker autoantibodies in anti-DFS70/LEDGF autoantibody–positive patients with autoimmune rheumatic disease
- (2008) Y Muro et al. LUPUS
- Alternative Splicing and Caspase-Mediated Cleavage Generate Antagonistic Variants of the Stress Oncoprotein LEDGF/p75
- (2008) T. A. Brown-Bryan et al. MOLECULAR CANCER RESEARCH
- A comparison of LEDGFp52 and CNTF on the in vitro growth of rat retinal ganglion cell neurites
- (2008) HaiSheng Zhao et al. NEUROSCIENCE LETTERS
- LEDGF binding to stress response element increases αB-crystallin expression in astrocytes with oxidative stress
- (2008) Joo-Hyun Shin et al. NEUROSCIENCE LETTERS
- Naturally occurring auto-antibodies in homeostasis and disease
- (2008) Hans U. Lutz et al. TRENDS IN IMMUNOLOGY
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