LEDGF (p75) promotes DNA-end resection and homologous recombination

Inhibition of the Interaction between HIV-1 Integrase and its Cofactor LEDGF/p75: A Promising Approach in Anti-Retroviral Therapy

(2012) L. De Luca et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Lens Epithelium-derived Growth Factor/p75 Qualifies as a Target for HIV Gene Therapy in the NSG Mouse Model

(2012) Sofie Vets et al.   MOLECULAR THERAPY

Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1

(2011) Valerie Garcia et al.   NATURE

Small molecules targeting the interaction between HIV-1 integrase and LEDGF/p75 cofactor

(2010) Laura De Luca et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Quantitative Interaction Proteomics and Genome-wide Profiling of Epigenetic Histone Marks and Their Readers

(2010) Michiel Vermeulen et al.   CELL

Break-induced replication: What is it and what is it for?

(2010) Bertrand Llorente et al.   CELL CYCLE

The Dnmt3a PWWP Domain Reads Histone 3 Lysine 36 Trimethylation and Guides DNA Methylation

(2010) Arunkumar Dhayalan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase

(2010) Halfdan Beck et al.   JOURNAL OF CELL BIOLOGY

Regulation of Chromatin Architecture by the PWWP Domain-Containing DNA Damage-Responsive Factor EXPAND1/MUM1

(2010) Michael S.Y. Huen et al.   MOLECULAR CELL

DNA resection in eukaryotes: deciding how to fix the break

(2010) Pablo Huertas   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1

(2010) Alessandro Vezzoli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

High-resolution profiling of the LEDGF/p75 chromatin interaction in the ENCODE region

(2010) Jan De Rijck et al.   NUCLEIC ACIDS RESEARCH

At Loose Ends: Resecting a Double-Strand Break

(2009) Kara A. Bernstein et al.   CELL

Transcriptional Co-activator LEDGF Interacts with Cdc7-Activator of S-phase Kinase (ASK) and Stimulates Its Enzymatic Activity

(2009) Siobhan Hughes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lens Epithelium-derived Growth Factor/p75 Interacts with the Transposase-derived DDE Domain of PogZ

(2009) Koen Bartholomeeusen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CtIP Links DNA Double-Strand Break Sensing to Resection

(2009) Zhongsheng You et al.   MOLECULAR CELL

Regulation of Set9-Mediated H4K20 Methylation by a PWWP Domain Protein

(2009) Yu Wang et al.   MOLECULAR CELL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Human Mismatch Repair Protein MSH6 Contains a PWWP Domain That Targets Double Stranded DNA†

(2008) Cédric Laguri et al.   BIOCHEMISTRY

Menin Critically Links MLL Proteins with LEDGF on Cancer-Associated Target Genes

(2008) Akihiko Yokoyama et al.   CANCER CELL

Mechanisms Governing Lentivirus Integration Site Selection

(2008) Angela Ciuffi   CURRENT GENE THERAPY

Identification and Characterization of PWWP Domain Residues Critical for LEDGF/p75 Chromatin Binding and Human Immunodeficiency Virus Type 1 Infectivity

(2008) M.-C. Shun et al.   JOURNAL OF VIROLOGY

Alternative Splicing and Caspase-Mediated Cleavage Generate Antagonistic Variants of the Stress Oncoprotein LEDGF/p75

(2008) T. A. Brown-Bryan et al.   MOLECULAR CANCER RESEARCH

Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair

(2008) Nicole Bennardo et al.   PLoS Genetics

DNA repair in response to anthracycline–DNA adducts: A role for both homologous recombination and nucleotide excision repair

(2007) Damian M.S. Spencer et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS