Gene silencing of non-obese diabetic receptor family (NLRP3) protects against the sepsis-induced hyper-bile acidaemia in a rat model

Ursodeoxycholic acid stabilizes the bile salt export pump in the apical membrane in MDCK II cells

(2013) Tatehiro Kagawa et al.   JOURNAL OF GASTROENTEROLOGY

IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease

(2013) Amina A. Negash et al.   PLoS Pathogens

The hepatic bile acid transporters Ntcp and Mrp2 are downregulated in experimental necrotizing enterocolitis

(2012) Nathan J. Cherrington et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

(2012) Vijay A.K. Rathinam et al.   CELL

Role of Inflammasomes in Host Defense againstCitrobacter rodentiumInfection

(2012) Zhiping Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bile acid transporters and regulatory nuclear receptors in the liver and beyond

(2012) Emina Halilbasic et al.   JOURNAL OF HEPATOLOGY

Expression analysis of inflammasomes in experimental models of inflammatory and fibrotic liver disease

(2012) Sorina Georgiana Boaru et al.   Journal of Inflammation-London

Liver Dysfunction and Phosphatidylinositol-3-Kinase Signalling in Early Sepsis: Experimental Studies in Rodent Models of Peritonitis

(2012) Peter Recknagel et al.   PLOS MEDICINE

Bile Acids Induce Inflammatory Genes in Hepatocytes

(2011) Katryn Allen et al.   AMERICAN JOURNAL OF PATHOLOGY

Critical illness evokes elevated circulating bile acids related to altered hepatic transporter and nuclear receptor expression

(2011) Yoo-Mee Vanwijngaerden et al.   HEPATOLOGY

Increased Survival and Reduced Neutrophil Infiltration of the Liver in Rab27a- but Not Munc13-4-Deficient Mice in Lipopolysaccharide-Induced Systemic Inflammation

(2011) Jennifer L. Johnson et al.   INFECTION AND IMMUNITY

Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver

(2011) Michal Ganz   WORLD JOURNAL OF GASTROENTEROLOGY

Gene Silencing of NALP3 Protects Against Liver Ischemia–Reperfusion Injury in Mice

(2010) Ping Zhu et al.   HUMAN GENE THERAPY

Granzyme B is a novel interleukin-18 converting enzyme

(2010) Youichi Omoto et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

(2010) Teresa Fernandes-Alnemri et al.   NATURE IMMUNOLOGY

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

(2010) B. McDonald et al.   SCIENCE

Conditional RNAi: Towards a silent gene therapy

(2009) Sang-Kyung Lee et al.   ADVANCED DRUG DELIVERY REVIEWS

The Role of Liver Sinusoidal Cells in Hepatocyte-Directed Gene Transfer

(2009) Frank Jacobs et al.   AMERICAN JOURNAL OF PATHOLOGY

Nuclear receptor ligands in therapy of cholestatic liver disease

(2009) Ekkehard Sturm   Frontiers in Bioscience-Landmark

The enterohepatic circulation of bile acids in mammals: form and functions

(2009) Alan et al.   Frontiers in Bioscience-Landmark

Rapid quantification of bile acids and their conjugates in serum by liquid chromatography–tandem mass spectrometry

(2009) Max Scherer et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Listeria monocytogenes-Infected Human Peripheral Blood Mononuclear Cells Produce IL-1 , Depending on Listeriolysin O and NLRP3

(2009) K. Meixenberger et al.   JOURNAL OF IMMUNOLOGY

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFN  production

(2009) H. P. Lemos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

(2009) S. S. Iyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of damage associated molecular pattern molecules in acetaminophen-induced liver injury in mice

(2009) Brittany V. Martin-Murphy et al.   TOXICOLOGY LETTERS

Caspase-1 Activation in Macrophages Infected with Yersinia pestis KIM Requires the Type III Secretion System Effector YopJ

(2008) S. Lilo et al.   INFECTION AND IMMUNITY