The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load

Double Blockade of CD14 and Complement C5 Abolishes the Cytokine Storm and Improves Morbidity and Survival in Polymicrobial Sepsis in Mice

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Combined Inhibition of Complement and CD14 Efficiently Attenuated the Inflammatory Response Induced by Staphylococcus aureus in a Human Whole Blood Model

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Post challenge inhibition of C3 and CD14 attenuates Escherichia coli-induced inflammation in human whole blood

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Chimeric Anti-CD14 IGG2/4 Hybrid Antibodies for Therapeutic Intervention in Pig and Human Models of Inflammation

(2013) C. Lau et al.   JOURNAL OF IMMUNOLOGY

An international serum standard for application in assays to detect human complement activation products

(2013) Grethe Bergseth et al.   MOLECULAR IMMUNOLOGY

New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties

(2012) Hongchang Qu et al.   IMMUNOBIOLOGY

Would Earlier Microbe Identification Alter Antibiotic Therapy in Bacteremic Emergency Department Patients?

(2012) Lisa R. Stoneking et al.   JOURNAL OF EMERGENCY MEDICINE

After Xigris, researchers look to new targets to combat sepsis

(2012) Sarah C P Williams   NATURE MEDICINE

Nationwide Trends of Severe Sepsis in the 21st Century (2000–2007)

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Toll-Like Receptors (TLRs) in Innate Immune Defense Against Staphylococcus Aureus

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Crosstalk between Complement and Toll-Like Receptors

(2011) Wen-Chao Song   TOXICOLOGIC PATHOLOGY

Multiplex cytokine profiling in patients with sepsis

(2010) SIMONA MERA et al.   APMIS

The complement system

(2010) J. Vidya Sarma et al.   CELL AND TISSUE RESEARCH

Complement activation in septic baboons detected by neoepitope-specific assays for C3b/iC3b/C3c, C5a and the terminal C5b-9 complement complex (TCC)

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The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis

(2010) Mitchell M. Levy et al.   INTENSIVE CARE MEDICINE

CD14 is a coreceptor of Toll-like receptors 7 and 9

(2010) Christoph L. Baumann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Harmful Role of C5a on Innate Immunity in Sepsis

(2010) Peter A. Ward   Journal of Innate Immunity

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Crosstalk pathways between Toll-like receptors and the complement system

(2010) George Hajishengallis et al.   TRENDS IN IMMUNOLOGY

Serial cytokine levels in patients with severe sepsis

(2009) Huang-Pin Wu et al.   INFLAMMATION RESEARCH

Human genetic deficiencies reveal the roles of complement in the inflammatory network: Lessons from nature

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Molecular biology of inflammation and sepsis: A primer*

(2008) Ismail Cinel et al.   CRITICAL CARE MEDICINE

Stages of Meningococcal Sepsis Simulated In Vitro, with Emphasis on Complement and Toll-Like Receptor Activation

(2008) B. C. Hellerud et al.   INFECTION AND IMMUNITY

Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36

(2008) Nadra J. Nilsen et al.   JOURNAL OF LEUKOCYTE BIOLOGY