Article
Spectroscopy
Denis S. Irisov, Rustam Kh Musin, Yuri A. Zakharov
Summary: A new two-stage probe atomization method was proposed for determining total arsenic in urine, using a high-resolution continuum source graphite furnace atomic absorption spectrometer. This method effectively separates arsenic from matrix components, with a low detection limit and a wide quantification range.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Mikhail Yu Burylin, Elena S. Kopeyko, Viktoriya A. Bauer
Summary: The study compared the determination characteristics of copper and manganese in seawater by high-resolution continuum-source and low-resolution line-source graphite furnace atomic absorption spectrometry. HR-CS GFAAS can determine elements in undiluted samples, while LR-LS GFAAS only allows determination at double dilution. The detection and quantification limits for manganese were significantly lower in HR-CS GFAAS.
ANALYTICAL LETTERS
(2022)
Review
Instruments & Instrumentation
David J. Butcher
Summary: Graphite furnace atomic absorption spectrometry (GFAAS) is a highly sensitive method for determining elements in samples with low sample volume requirements. While line-source GFAAS is widely used, high-resolution continuum source (HR-CS) GFAAS allows for more accurate correction of matrix-induced spectral backgrounds. This article reviews recent innovations and developments in GFAAS, including instrumentation, characterization of fundamental properties, progress in HR-CS GFAAS, sample preparation procedures, elemental speciation, preconcentration/separation protocols, and direct analysis.
APPLIED SPECTROSCOPY REVIEWS
(2023)
Article
Biochemical Research Methods
Alexander Winckelmann, Dalia Morcillo, Silke Richter, Sebastian Recknagel, Jens Riedel, Jochen Vogl, Ulrich Panne, Carlos Abad
Summary: A fast, simple, and cost-effective analytical procedure for traceable determination of lithium concentration in human serum has been proposed. The method is based on monitoring lithium isotope dilution through the partially resolved isotope shift in its electronic transition. The results are comparable to more complex and expensive techniques such as isotope dilution mass spectrometry.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Review
Instruments & Instrumentation
David J. Butcher
Summary: Graphite furnace atomic absorption spectrometry (GFAAS), also known as electrothermal atomization (ETAAS), is a widely used method for sensitive elemental analysis. This article provides a summary of its principles, recent developments, and applications. The advancements in atomization mechanisms and instrumentation, as well as new approaches for direct solid sampling (SS) and preconcentration, are discussed. The article also reviews direct analyses for various sample types and discusses future developments in green protocols and speciation analyses in GFAAS.
APPLIED SPECTROSCOPY REVIEWS
(2023)
Article
Chemistry, Analytical
Maiara Maziero, Franciele Rovasi Adolfo, Gabriela Camera Leal, Leandro Machado de Carvalho, Paulo Cicero do Nascimento, Carine Viana
Summary: The development of a method for determining Al, Cd, Cu, Mo, and Pb in pharmaceuticals for patients with chronic kidney disease using high-resolution continuum source graphite furnace atomic absorption spectrometry (HR-CS GFAAS) after microwave-assisted acid digestion is reported. The method involved utilizing different chemical modifiers and temperature conditions for the analysis of the elements, with successful application in 50 pharmaceutical formulations.
ANALYTICAL LETTERS
(2022)
Article
Spectroscopy
Ondrej Zverina, Monika Vychytilov, Jaqueline Rieger, Walter Goessler
Summary: This article presents a rapid and accurate method for determining the zinc and iron content in food using high-resolution continuum source graphite-furnace atomic absorption spectrometry. By monitoring a narrow spectral interval, both elements can be measured simultaneously in a single firing, making the analysis fast and sensitive. Analysis of a large set of vegetable samples indicates higher zinc and iron contents in homegrown vegetables compared to store-bought ones.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2023)
Article
Chemistry, Analytical
Zofia Kowalewska, Carlos Abad, Michael Okruss, Sebastian Recknagel
Summary: This study aimed to evaluate the potential of high-resolution continuum source molecular absorption spectrometry (HR-CS MAS) in determining the new element vanadium. Using VO as the target molecule, high-resolution overview spectra were obtained and analyzed in a wide range of wavelengths. A unique instrumental setup combining a prototype Modular Simultaneous Echelle Spectrograph (MOSES) and a commercial HR-CS MAS apparatus was employed. The results showed that HR-CS MAS can be used to determine vanadium in heavy petroleum oil catalysts using a flame version of the spectrometer. However, the sensitivity was relatively poor and only a small population of VO molecules could be generated in graphite furnace measurements.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2023)
Article
Chemistry, Analytical
Arlene Santos Silva, Geovani Cardoso Brandao, Sergio Luis Costa Ferreira, Ana Maria Pinto dos Santos
Summary: An analytical method for the multielemental determination of Cd, Fe and Ni in toothpaste using slurry sampling high-resolution continuum source electrothermal atomic absorption spectrometry (HR-CS ET AAS) was reported. The method was successfully applied to analyze five toothpaste samples of different brands, demonstrating accurate and reliable results.
ANALYTICAL LETTERS
(2022)
Article
Chemistry, Analytical
Siyu Gu, Xudong Huang, Mingli Chen, Jixin Liu, Xuefei Mao, Xing Na, Guoying Chen, Yunbin Shao
Summary: A novel IDBD reactor coupled with ETV was established for arsenic determination, investigating the evolution mechanisms of arsenic species using XPS. DBDA atomizes arsenic nanoparticles while DBDT traps and releases arsenic oxides, enhancing sensitivity and precision in seafood sample analysis. The method shows potential for rapid arsenic analysis based on direct solid sampling ETV instrumentation.
ANALYTICAL CHEMISTRY
(2021)
Article
Geochemistry & Geophysics
Norbert Schreiter, Oliver Wiche, Ines Aubel, Quirina Roode-Gutzmer, Martin Bertau
Summary: A modified AAS method using HR CS GFAAS was developed for the determination of Ge in solid samples, without the need for time-consuming sample preparation steps. The results obtained showed a good agreement with those obtained using ICP-MS. The detection limit for Ge was down to 500 μg kg(-1), making the method suitable for routine analysis in geochemical laboratories.
JOURNAL OF GEOCHEMICAL EXPLORATION
(2021)
Article
Chemistry, Multidisciplinary
Andrzej Gawor, Andrii Tupys, Anna Ruszczynska, Ewa Bulska
Summary: The determination of trace amounts of fluorine in biological samples poses challenges due to the chemically-rich matrix of biological tissues. High-resolution continuum source graphite furnace molecular absorption spectrometry (HR-CS GF MAS) is an effective method for precise fluorine determination, especially when optimized experimental conditions are employed. This method was validated through the use of certified reference materials, demonstrating its applicability to samples with similar matrices.
APPLIED SCIENCES-BASEL
(2021)
Article
Chemistry, Analytical
Artyom V. Volzhenin, Natalya Petrova, Tamara E. Romanova, Anatoly Saprykin
Summary: This study developed a novel procedure for determining Cd, Pb, and Zn in mussels by combining TPA and GFAAS, which eliminated organic matrix interferences and reduced sample pretreatment processes. The heavy metal concentrations in mussel tissues from the Sea of Japan were found to have no negative effects on human health.
ANALYTICAL LETTERS
(2021)
Article
Chemistry, Analytical
Yaru Zhang, Xuefei Mao, Di Tian, Jixin Liu, Chunsheng Li
Summary: A novel method using low-cost miniaturized hydride generation optical emission spectrometry equipment coupled with an in situ dielectric barrier discharge trap was developed for the determination of As in edible seaweed samples. The method significantly improved the linear range and sensitivity, with a detection limit of 0.2 μg L-1. Application of the method to seaweed samples yielded a method detection limit of 0.25 mg kg(-1) with good accuracy and precision.
ANALYTICAL METHODS
(2021)
Article
Biochemistry & Molecular Biology
Amir Ghaderi, Amir Hossein Khoshakhlagh, Masoome Irani, Azam Ghaseminezhad, Prem Gautam, Nezam Mirzaei, Hamid Reza Banafshe, Bahador Nemati, Heshmatollah Moradpour Ghalerashidi
Summary: This study investigated the levels of heavy metals and elements in urine and blood of hookah users and non-users, as well as their clinical symptoms. Results showed significantly higher levels of lead, arsenic, and thallium in hookah users compared to non-users, along with common clinical symptoms of constipation and fatigue. These findings can guide policy development to regulate hookah smoking and prevent associated health risks.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Chemistry, Analytical
Diogo Cherem Morelli, Leila Doracio Mendes, Eduardo Carasek, Luiz Augusto Santos Madureira
Summary: In this study, a simple, robust, and efficient method for determining faecal contaminants in sediment samples was developed using ultrasound-assisted extraction (UAE) and disposable pipette extraction (DPX). The optimized method showed potential for accurate and fast analysis of faecal sterols in sediment samples.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Analytical
Eduardo Carasek, Lucas Mores, Ricardo Dagnoni Huelsmann
Summary: The translation introduces a new sample preparation method – Disposable Pipette Extraction (DPX), which achieves rapid and effective extraction of analytes through dynamic mixing and contributes to reducing waste generation and improving laboratory worker safety by using natural materials to replace commercial ones.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Wladiana O. Matos, Francisco L. F. da Silva, Savarin Sinaviwat, Andrea Raab, Eva M. Krupp, Gisele S. Lopes, Ana R. A. Nogueira, Joerg Feldmann
Summary: This study evaluated the shrimp production cycle and focused on the accumulation of trace elements in shrimps and effluent. The results showed secure levels of elements in the final product, while the effluent from farms was found to be a significant source of contamination to the mangrove environment.
ENVIRONMENTAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Joerg Feldmann
ENVIRONMENTAL CHEMISTRY
(2023)
Article
Chemistry, Applied
Julia Monika Dressler, Andrea Raab, Silvia Wehmeier, Joerg Feldmann
Summary: A survey was conducted on 51 rice samples from the Austrian market, revealing that the average concentrations of inorganic arsenic in rice, rice products, and baby foods were 120 μg/kg, 191 μg/kg, and 77 μg/kg, respectively. Most rice samples had cadmium and lead levels below the European maximum levels. Upland grown rice from Austria exhibited low concentrations of inorganic arsenic (<19 μg/kg) and cadmium (<38 μg/kg).
FOOD ADDITIVES & CONTAMINANTS PART B-SURVEILLANCE
(2023)
Article
Chemistry, Analytical
Francielle Crocetta Turazzi, Lucas Mores, Eduardo Carasek, Guilherme Mariz de Oliveira Barra
Summary: Different polyanilines were synthesized and evaluated for the determination of three hormones in urine samples. The optimized extraction conditions and calibration curves were established, and the method showed satisfactory detection and quantification limits, as well as good recoveries and precision. The method was successfully applied to analyze urine samples from female volunteers.
JOURNAL OF SEPARATION SCIENCE
(2023)
Article
Water Resources
Shaun Lancaster, Warren T. Corns, Eva M. Krupp, Joerg Feldmann
Summary: This article introduces a new analyzer for online monitoring of mercury in flue gas desulfurization wastewater, based on syringe injections of chemicals combined with gold amalgamation - atomic fluorescence spectrometry. The instrument has been validated and proven to meet the new legislation requirements.
WATER QUALITY RESEARCH JOURNAL
(2023)
Article
Engineering, Environmental
Viktoria Mueller, Andrew Kindness, Joerg Feldmann
Summary: Wastewater treatment plants are a significant source of PFAS in the environment. This study analyzed influent, effluent, and sludge from two wastewater treatment plants in Austria for target PFAS compounds and extractable organic fluorine content. The results showed that the sum of target PFAS increased from influent to effluent, with higher concentrations in effluent and sludge. Mass balance analysis suggested the biotransformation of non-targeted PFAS precursor compounds.
Article
Chemistry, Multidisciplinary
Diogo M. Betiolo, Heloisa R. Cadorim, Eduardo Carasek, Tatiane A. Maranhao
Summary: The use of disposable tips (DPX) for extraction of Yb in liquid waste samples using bioabsorbent cork and analysis by HR-CS GF AAS was evaluated. The optimal conditions for temperature, acid selection, and pH were determined, and recoveries close to 100% were achieved for residual and drinking water samples. Interference tests were performed, and the LOQ and LOD were estimated at 0.03 and 0.01 μg L-1, respectively. The use of DPX allowed for extraction and preconcentration of Yb with a preenrichment factor of approximately 4 times.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Lucas Mores, Ricardo D. Huelsmann, Gabrieli Bernardi, Josias Merib, Eduardo Carasek
Summary: Lung cancer is a leading cause of death worldwide. Biomarker aldehydes, such as hexanal and heptanal, are associated with the development of lung cancer and can be detected in early stages of the disease. A new methodology using parallel-disposable pipette extraction (DPX)-cork device was proposed for the determination of these aldehydes in urine. The method showed good precision and recovery, with low limits of detection and quantification for hexanal and heptanal. However, aldehydes were not detected in the analyzed urine samples.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Analytical
Rebecca Sim, Joerg Feldmann, Dagmar B. Stengel, Asta H. Petursdottir
Summary: This study investigates the origins of arsenosugars in common seaweed species. The results suggest that arsenosugars are a by-product of normal biological activity, rather than a detoxification pathway for inorganic arsenic.
ENVIRONMENTAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Zuzana Gajdosechova, Patricia Grinberg, Kevin Kubachka, Mesay Wolle, Andrea Raab, Joerg Feldmann, Rebecca Sim, asta H. Petursdottir, Tomas Matousek, Stanislav Musil, Ben Wozniak, Stephen Springer, Nausheen W. Sadiq, Hakan Gurleyuk, Calvin H. Palmer, Indumathi Pihillagawa Gedara, Zoltan Mester
Summary: The study aimed to investigate the issues in arsenic speciation analysis in biological matrices and validate the analytical methods. An international round-robin study showed that inadequate verification of the analyte's mass fractions in calibration standard solutions could introduce significant biases. The choice of extraction method had minimal impact on quantitation of arsenic species in plant and terrestrial biological tissues, but following a prescribed extraction method resulted in reduced uncertainties in complex samples such as marine animal tissues.
ENVIRONMENTAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Georg Raber, Sonja Weishaupt, Fabian Lappi, Michael Stiboller, Joerg Feldmann
Summary: A new analytical method using gas chromatography-mass spectrometry (GC-MS) was developed for the quantitative determination of arsenic-containing hydrocarbons (AsHCs) in marine samples. The novel method allows for compound independent quantification using triphenylarsine (TPA) as a commercially available standard, expanding the screening application for these toxic compounds in the environment.
ENVIRONMENTAL CHEMISTRY
(2023)
Article
Biochemical Research Methods
Silvia Wehmeier, Marc Preihs, Julia Dressler, Andrea Raab, Joerg Feldmann
Summary: Rice, a staple food, is known for its accumulation of inorganic arsenic (iAs), a known carcinogen. Field-deployable kits designed for water testing can screen iAs in rice, ensuring food safety without the need for laboratory analysis. By adapting the extraction process to include Cola, the field method becomes safer, cost-effective, and easier to handle. Testing on Austrian rice products showed that most samples were within the European Union's iAs limits.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Viktoria Mueller, Larissa Cristine Andrade Costa, Filipe Soares Rondan, Eleonora Matic, Marcia Foster Mesko, Andrew Kindness, Joerg Feldmann
Summary: This study analyzed ski waxes, snowmelts, and soil samples from family skiing areas in Alpine locations to investigate the distribution of PFAS in the environment. The researchers found a diverse pattern of PFAS in the analyzed media, with higher levels in skiing areas compared to non-skiing areas. Snowmelt was dominated by short-chained PFAS, while soil and wax contained both short and long-chained PFAS. The study highlights the importance of non-targeted analysis and extractable organic fluorine (EOF) for a better understanding of PFAS distribution.
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2023)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).
