Article
Multidisciplinary Sciences
Nivedita, Abdul Rawoof, Nirala Ramchiary, Malik Z. Abdin
Summary: Transcriptome analysis of P. indica under salt stress revealed 661 differentially expressed genes mainly involved in metabolic and molecular processes such as response to salt stress and oxidoreductase activity. Genes related to cell wall integrity, sterol biosynthesis, and oxidative stress were up-regulated in P. indica subjected to salt stress. These salt-responsive DEGs may play a potential role in salt stress regulation.
SCIENTIFIC REPORTS
(2021)
Article
Microbiology
Zhenzhu Su, Yulan Zeng, Xiaoli Li, Anand Babu Perumal, Jianan Zhu, Xuanjun Lu, Mengdi Dai, Xiaohong Liu, Fucheng Lin
Summary: The endophytic fungus Piriformospora indica has been shown to enhance plant tolerance to heavy metals such as cadmium (Cd). This study investigated how P. indica helps tobacco plants overcome Cd toxicity, revealing changes in Cd accumulation, subcellular distribution, and enzyme activity. Through extensive physiological, cytological, and proteomic analyses, the study demonstrated that P. indica enhances Cd tolerance in tobacco by modulating the subcellular allocation of Cd and increasing the activity of antioxidant enzymes like peroxidase.
Article
Agronomy
Mayra Gonzalez-Delgado, Rafael Minjares-Fuentes, Maria Mota-Ituarte, Aurelio Pedroza-Sandoval, Francesca Comas-Serra, Jesus Josafath Quezada-Rivera, Angeles Saenz-Esqueda, Antoni Femenia
Summary: This study aimed to evaluate the effects of joint water and salinity stresses on the bioactive compounds and functional properties of Aloe vera gel. The results showed that water + salinity stress had a negative impact on the plants' development, but significantly increased the total dry matter content. Furthermore, it caused changes in the bioactive compounds and functional properties, suggesting that water + salinity stress can increase the content of bioactive compounds and improve their functional properties in Aloe vera gel.
AGRICULTURAL WATER MANAGEMENT
(2023)
Article
Engineering, Environmental
Saeed ur Rahman, Muhammad Khalid, Nan Hui, Asad Rehman, Sadaf-Ilyas Kayani, Xueqing Fu, Han Zheng, Jin Shao, Abid Ali Khan, Mehran Ali, Ayat Taheri, Hang Liu, Xin Yan, Xinyi Hu, Wei Qin, Bowen Peng, Meng Li, Yao Xinghao, Yaojie Zhang, Kexuan Tang
Summary: Microorganisms in the rhizosphere play a crucial role in plant stress tolerance, and recent research suggests that they can aid in the revegetation of soils contaminated with heavy metal(loid)s. However, the influence of Piriformospora indica on the rhizosphere microbiome in arsenic-enriched environments is still unknown. In this study, P. indica inoculation altered the rhizosphere microecology and mitigated arsenic-toxicity without harming the environment.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Plant Sciences
Weiting Chen, Fazhuang Lin, Kuan-Hung Lin, Changming Chen, Chaoshui Xia, Qiaoling Liao, Shi-Peng Chen, Yun-Wei Kuo
Summary: The colonization of the fungus Piriformospora indica positively impacts the growth and salt resistance of Gerbera jamesonii seedlings, leading to increased biomass, enhanced photosynthesis, and improved tolerance to salt stress. This interaction also results in reduced malondialdehyde and hydrogen peroxide levels in plants exposed to salt treatment. Differential expressions of sodium transporter genes and aquaporin genes were observed in gerbera plants after P. indica colonization, highlighting the role of plant-microbe interaction in promoting plant performance under stress conditions.
JOURNAL OF PLANT GROWTH REGULATION
(2022)
Article
Agronomy
Zahra Aslani, Abbas Hassani, Babak Abdollahi Mandoulakani, Mohsen Barin, Ramin Maleki
Summary: This study examined the potential of plant beneficial rhizospheric microorganisms (PBRMs) in improving the tolerance of sage plants to salinity stress. The results showed that symbiotic association with PBRMs can help sage plants overcome the adverse effects of salinity stress.
Article
Horticulture
Maryam Azizi, Ehsan Mohseni Fard, Mehdi Ghabooli
Summary: The present study demonstrates that the endophytic fungus Piriformospora indica can enhance the tolerance of tomato plants to drought stress by improving plant growth and morpho-physiological parameters. The sensitive cultivar exhibited poorer performance under drought conditions, while the tolerant cultivar showed better growth. Colonization by the fungus increased the measured factors in both tomato cultivars, and gene expression analysis revealed a synergistic effect of the fungus and drought treatments on certain genes.
SCIENTIA HORTICULTURAE
(2021)
Article
Plant Sciences
Qing Li, Yun-Wei Kuo, Kuan-Hung Lin, Weiqun Huang, Caisheng Deng, Kai-Wun Yeh, Shi-Peng Chen
Summary: Piriformospora indica symbiosis enhances growth and photosynthesis, while also boosting resistance against insect herbivory in sweet potato by regulating sporamin-dependent defense. The root symbiosis of P. indica promotes biomass accumulation, photosynthetic pigment content, and jasmonic acid-mediated defense in sweet potato plants, leading to increased resistance against herbivores such as Spodoptera litura.
PLANT CELL REPORTS
(2021)
Article
Medicine, Research & Experimental
Behrad Darvishi, Rassoul Dinarvand, Hadiseh Mohammadpour, Tunku Kamarul, Ali Mohammad Sharifi
Summary: Microvascular complications in patients with uncontrolled hyperglycemia in type II diabetes mellitus are mainly caused by the overproduction and accumulation of MGO, which can be neutralized by a combination of L-carnosine and Aloe vera to improve angiogenic responses and microvascular dysfunction. Additionally, nanophytosomal formulations of the dual compounds show superior effects in protecting cells, scavenging free radicals, synthesizing nitric oxide, improving cell viability, and enhancing gene expression related to angiogenesis.
MOLECULAR PHARMACEUTICS
(2021)
Article
Polymer Science
Maria Carolina Otalora, Andrea Wilches-Torres, Jovanny A. Gomez Castano
Summary: This study compared the molecular, morphological, thermal properties, and dietary fiber content of mucilage in cacti and aloe vera plants. The results demonstrated that cactus mucilage exhibited superior thermal stability and dietary fiber content compared to aloe vera mucilage.
Article
Agronomy
Rita Maggini, Stefano Benvenuti, Federico Leoni, Luca Incrocci, Alberto Pardossi
Summary: Wild edible plant species are more salt-tolerant than many crop plants, and cultivation of these species under salt treatment can increase bioactive molecule content and reduce nitrate ion levels.
Article
Biotechnology & Applied Microbiology
Fuad Ameen, Steven L. Stephenson, Saleh AlNadhari, Mohamed A. Yassin
Summary: Endophytic fungi isolated from desert plants, such as Preussia africana from Aloe vera, show promising bioactivities including strong antioxidant and wound healing effects, as well as activity against various cancer cell lines, indicating their wide therapeutic potential against severe diseases.
BIOPROCESS AND BIOSYSTEMS ENGINEERING
(2021)
Article
Polymer Science
Maria Carolina Otalora, Andrea Wilches-Torres, Jovanny A. Gomez Castano
Summary: This work studied the use of mucilage extracted from the cladodes of Opuntia ficus-indica and aloe vera leaves as wall material in the microencapsulation of pink guava carotenoids using spray-drying. The results showed that the use of aloe vera mucilage increased the retention of beta-carotene, antioxidant capacity, and total carotenoid content of the microcapsules.
Article
Agronomy
Constantin Lungoci, Iuliana Motrescu, Feodor Filipov, Carmenica Doina Jitareanu, Gabriel-Ciprian Teliban, Carmen Simona Ghitau, Ioan Puiu, Teodor Robu
Summary: This study tested the ability of Nepeta cataria L. to grow and synthesize bioactive compounds in soil with different salt concentrations. The results showed that high salinity stress inhibited plant growth, but increased the density of granular trichomes as a defense mechanism. The chlorophyll content varied with salt concentration, while antioxidant activity played a protective role against salinity stress.
Article
Agricultural Engineering
Ece Turedi, Nil Acarali
Summary: This study investigated the effectiveness and stability of black cumin, lemon balm, and Aloe vera essences in cosmetic creams. The essences were selected for their beneficial biological activities and were subjected to stability tests at different temperatures. The experiments revealed that the physical and chemical properties of the creams were affected by temperature. Additionally, the study found that the pH value of the herbal cream samples was suitable for skincare. The essence obtained from Aloe vera was also tested and optimized for its effects on the samples.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Oncology
Shehla Adhami, Humaira Farooqi, Malik Z. Abdin, Ram Prasad, Asrar A. Malik
Summary: This study identified the chemical composition of Chlorophytum comosum and demonstrated its significant antiproliferative effects against lung and breast cancer cell lines, while showing no impact on normal cell lines.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
(2021)
Article
Multidisciplinary Sciences
Nivedita, Abdul Rawoof, Nirala Ramchiary, Malik Z. Abdin
Summary: Transcriptome analysis of P. indica under salt stress revealed 661 differentially expressed genes mainly involved in metabolic and molecular processes such as response to salt stress and oxidoreductase activity. Genes related to cell wall integrity, sterol biosynthesis, and oxidative stress were up-regulated in P. indica subjected to salt stress. These salt-responsive DEGs may play a potential role in salt stress regulation.
SCIENTIFIC REPORTS
(2021)
Article
Genetics & Heredity
Vishesh Kumar, Priyanka Jain, Sureshkumar Venkadesan, Suhas Gorakh Karkute, Jyotika Bhati, Malik Zainul Abdin, Amitha Mithra Sevanthi, Dwijesh Chandra Mishra, Krishna Kumar Chaturvedi, Anil Rai, Tilak Raj Sharma, Amolkumar U. Solanke
Summary: This study analyzed the transcriptome of rice plants in response to panicle blast infection, identifying key genes involved in defense response, cell wall strengthening pathways, and potential mechanisms of panicle blast resistance. Understanding these mechanisms could aid in breeding resistant rice varieties.
Review
Neurosciences
Saman Fatima, Syed Naved Quadri, Shaheda Parveen, Sarwar Beg, Md Abul Barkat, M. Samim, M. Z. Abdin, Farhan Jalees Ahmad
Summary: Ischemic stroke is the second leading cause of mortality and morbidity globally due to the lack of effective therapy; research on neuroprotectants may benefit a larger population of stroke patients; the application of nanovehicles for drug delivery could revolutionize the treatment of ischemic stroke.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS
(2021)
Review
Genetics & Heredity
Ankit Gupta, Krishna Murari Sinha, Malik Z. Abdin, Niti Puri, Angamuthu Selvapandiyan
Summary: Currently, there is no effective vaccine for parasitic diseases, leading to a reliance on chemotherapy that is threatened by drug resistance in parasites. NDKs of pathogens have diverse functions and can be classified into two groups, with potential for developing drugs targeting group 2 NDKs. This review provides insights into the structures and functions of human NMEs and pathogen NDKs, suggesting NDKs as potential drug targets.
Article
Biotechnology & Applied Microbiology
Bhawna Bonthala, M. Z. Abdin, Lalit Arya, Chithra D. Pandey, Vedprakash Sharma, Priya Yadav, Manjusha Verma
Summary: We developed 45,066 perfect SSR markers for bottle gourd through genome-wide analysis and utilized them for genetic diversity and population structure analysis of 96 accessions. The generated SSR markers provide a valuable tool for breeding and gene discovery in bottle gourd and other cucurbits species.
JOURNAL OF APPLIED GENETICS
(2022)
Article
Biotechnology & Applied Microbiology
Vishesh Kumar, Pankaj K. Singh, Suhas Gorakh Karkute, Mohd Tasleem, Someshwar Bhagat, M. Z. Abdin, Amitha Mithra Sevanthi, Anil Rai, Tilak Raj Sharma, Nagendra K. Singh, Amolkumar U. Solanke
Summary: In this study, researchers standardized an effective method for screening and evaluating panicle blast disease in rice. The method is simple, reliable, and suitable for large-scale screening of germplasm resources. Through gene expression analysis, the researchers evaluated the method at the phenotypic and molecular levels and successfully identified resistant wild rice genotypes and mutants.
Review
Plant Sciences
Koushik Halder, Abira Chaudhuri, Malik Z. Abdin, Manoj Majee, Asis Datta
Summary: The stress response of plants involves a complex network of signaling cascades that regulate transcriptional reprogramming to adapt to abiotic stress conditions. Changes in chromatin modification and DNA methylation have significant effects on the expression of stress-responsive genes. This review primarily focuses on chromatin restructuring under severe abiotic stresses, the crosstalk between epigenetic regulators, and the initial research on stress priming in plants.
Article
Chemistry, Multidisciplinary
Sadia Iqrar, Kudsiya Ashrafi, Shazia Khan, Monica Saifi, Nazima Nasrullah, Malik Zainul Abdin
Summary: This study identified and validated the role of miRNAs in the regulation of sulfur uptake and assimilation pathways in Brassica juncea. The findings highlight the potential implications of these molecules in enhancing sulfur content in the plant.
Article
Infectious Diseases
Mohammad Islamuddin, Abuzer Ali, Wajihul Hasan Khan, Amena Ali, Syed Kazim Hasan, Mohd Abdullah, Kentaro Kato, Malik Zainul Abdin, Shama Parveen
Summary: Chikungunya is a disease caused by an alpha virus transmitted by infected mosquitoes. Early and accurate diagnosis is crucial in managing the infection.
INFECTION AND DRUG RESISTANCE
(2022)
Article
Biotechnology & Applied Microbiology
Monica Saifi, Kudsiya Ashrafi, Nazima Nasrullah, Urvashi Bhardwaj, M. Z. Abdin
Summary: Computational analysis was used to identify miRNAs in T. cordifolia and predict their targets, revealing their potential importance in plant secondary metabolite improvement. Selected miRNAs were validated, and their expression in T. cordifolia tissues was analyzed along with their target gene expression.
Article
Chemistry, Multidisciplinary
Kudsiya Ashrafi, Sadia Iqrar, Monica Saifi, Shazia Khan, Firdaus Qamar, Syed Naved Quadri, Anuradha Mishra, Malik Zainul Abdin
Summary: This study evaluated the influence of different plant growth regulators on the density of glandular trichomes and the content of steviol glycosides in Stevia rebaudiana. The results showed that specific plant growth regulators significantly increased glandular trichome density in leaf and stem tissues of Stevia rebaudiana, leading to a notable increase in steviol glycosides and other valuable secondary metabolites. Thus, the developed protocol can be used for large-scale propagation of Stevia with improved metabolic profile.
Article
Multidisciplinary Sciences
Nazima Nasrullah, Javed Ahmad, Monica Saifi, Irum Gul Shah, Umara Nissar, Syed Naved Quadri, Kudsiya Ashrafi, Malik Zainul Abdin
Summary: Stevia contains commercially important steviol glycosides, and by over-expressing certain genes, the ratio of rebaudioside-A to stevioside can be increased. This increases the palatability and commercial viability of Stevia plants.
Article
Chemistry, Multidisciplinary
Sadia Iqrar, Kudsiya Ashra, Shazia Khan, Monica Sai, Nazima Nasrullah, Malik Zainul Abdin
Summary: This study identifies different miRNAs involved in the regulation of sulfur uptake and assimilation pathways in Brassica juncea, demonstrating their potential role through the correlation between miRNA expression pattern and target gene expression. The study also explores the implications of these miRNAs in enhancing the sulfur content of B. juncea.
Review
Plant Sciences
Koushik Halder, Abira Chaudhuri, Malik Z. Abdin, Manoj Majee, Asis Datta
Summary: RNA interference (RNAi) and CRISPR/Cas9 are important biotechnological tools in the field of agriculture. RNAi can improve disease resistance in plants, while CRISPR/Cas9 can be used to develop virus-resistant plants. In addition, the use of RNAi-induced dsRNA has great potential in various applications.
FRONTIERS IN PLANT SCIENCE
(2022)