Kras is Required for Adult Hematopoiesis

Kras Is Critical for B Cell Lymphopoiesis

(2016) Yuhong Chen et al.   JOURNAL OF IMMUNOLOGY

Loss of wild-type Kras promotes activation of all Ras isoforms in oncogenic Kras-induced leukemogenesis

(2016) G Kong et al.   LEUKEMIA

Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm

(2014) Guangyao Kong et al.   JOURNAL OF CLINICAL INVESTIGATION

Kit Regulates Maintenance of Quiescent Hematopoietic Stem Cells

(2014) L. A. Thoren et al.   JOURNAL OF IMMUNOLOGY

NrasG12D/+ promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions

(2013) J. Wang et al.   BLOOD

Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness

(2013) Qing Li et al.   NATURE

Targeting oncogenic Ras signaling in hematologic malignancies

(2012) A. F. Ward et al.   BLOOD

Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk

(2012) Karl Staser et al.   JOURNAL OF CLINICAL INVESTIGATION

Loss of CD44 attenuates aberrant GM-CSF signaling in Kras G12D hematopoietic progenitor/precursor cells and prolongs the survival of diseased animals

(2012) J Du et al.   LEUKEMIA

Endothelial and perivascular cells maintain haematopoietic stem cells

(2012) Lei Ding et al.   NATURE

Signaling Profiling at the Single-Cell Level Identifies a Distinct Signaling Signature in Murine Hematopoietic Stem Cells

(2012) Juan Du et al.   STEM CELLS

The Expression of the Glucocorticoid Receptor in Human Erythroblasts is Uniquely Regulated by KIT Ligand: Implications for Stress Erythropoiesis

(2012) Lilian Varricchio et al.   STEM CELLS AND DEVELOPMENT

Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner

(2011) J. Wang et al.   BLOOD

The Thrombopoietin/MPL pathway in hematopoiesis and leukemogenesis

(2011) Fu-Sheng Chou et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia

(2010) J. Wang et al.   BLOOD

Intermediate-Term Hematopoietic Stem Cells with Extended but Time-Limited Reconstitution Potential

(2010) Patricia Benveniste et al.   Cell Stem Cell

Developmentally induced Mll1 loss reveals defects in postnatal haematopoiesis

(2010) T Gan et al.   LEUKEMIA

The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease

(2009) T. R. Hercus et al.   BLOOD

Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon

(2008) Kevin M Haigis et al.   NATURE GENETICS

Of lineage and legacy: the development of mammalian hematopoietic stem cells

(2008) Elaine Dzierzak et al.   NATURE IMMUNOLOGY