Rac1 GTPase Promotes Interaction of Hematopoietic Stem/Progenitor Cell with Niche and Participates in Leukemia Initiation and Maintenance in Mouse

Advances in understanding the acute lymphoblastic leukemia bone marrow microenvironment: From biology to therapeutic targeting

(2016) Francesca Chiarini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Activation of the vascular niche supports leukemic progression and resistance to chemotherapy

(2014) Michael G. Poulos et al.   EXPERIMENTAL HEMATOLOGY

Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts

(2014) Aruna Kode et al.   NATURE

CD44 regulates the apoptotic response and promotes disease development in chronic lymphocytic leukemia

(2013) O. Fedorchenko et al.   BLOOD

Activation of Rac1 GTPase promotes leukemia cell chemotherapy resistance, quiescence and niche interaction

(2013) Ji-Ying Wang et al.   Molecular Oncology

Rho family GTPases

(2012) Alan Hall   BIOCHEMICAL SOCIETY TRANSACTIONS

IL-6 Controls Leukemic Multipotent Progenitor Cell Fate and Contributes to Chronic Myelogenous Leukemia Development

(2011) Damien Reynaud et al.   CANCER CELL

Robo4 Cooperates with Cxcr4 to Specify Hematopoietic Stem Cell Localization to Bone Marrow Niches

(2011) Stephanie Smith-Berdan et al.   Cell Stem Cell

Stem Cell Quiescence

(2011) L. Li et al.   CLINICAL CANCER RESEARCH

Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia

(2010) Marc H. G. P. Raaijmakers et al.   NATURE

Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1

(2010) Etienne Boulter et al.   NATURE CELL BIOLOGY

Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells

(2010) Hideki Kobayashi et al.   NATURE CELL BIOLOGY

The stem cell niche in health and malignancy

(2010) Monika L. Burness et al.   SEMINARS IN CANCER BIOLOGY

Overexpression of Rac1 in leukemia patients and its role in leukemia cell migration and growth

(2009) Jiying Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rho GTPases in hematopoiesis and hemopathies

(2009) J. C. Mulloy et al.   BLOOD

Contribution of bone microenvironment to leukemogenesis and leukemia progression

(2009) F Ayala et al.   LEUKEMIA

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

(2008) Z. Zeng et al.   BLOOD

Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100

(2008) B. Nervi et al.   BLOOD

The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation

(2008) Wendy A. Ciovacco et al.   BONE

Rac GTPases as key regulators of p210-BCR-ABL-dependent leukemogenesis

(2008) E K Thomas et al.   LEUKEMIA

Rac guanosine triphosphatases represent a potential target in AML

(2008) L U W Müller et al.   LEUKEMIA