Generation of Functional Human Retinal Ganglion Cells with Target Specificity from Pluripotent Stem Cells by Chemically Defined Recapitulation of Developmental Mechanism

Stepwise Differentiation of Retinal Ganglion Cells from Human Pluripotent Stem Cells Enables Analysis of Glaucomatous Neurodegeneration

(2016) Sarah K. Ohlemacher et al.   STEM CELLS

Retinal Organoids from Pluripotent Stem Cells Efficiently Recapitulate Retinogenesis

(2016) Manuela Völkner et al.   Stem Cell Reports

The genetic mechanisms of primary angle closure glaucoma

(2015) D F Ahram et al.   EYE

Continuous Non-Cell Autonomous Reprogramming to Generate Retinal Ganglion Cells for Glaucomatous Neuropathy

(2015) Sowmya Parameswaran et al.   STEM CELLS

Generation of retinal ganglion cells with functional axons from human induced pluripotent stem cells

(2015) Taku Tanaka et al.   Scientific Reports

Differentiation of human ESCs to retinal ganglion cells using a CRISPR engineered reporter cell line

(2015) Valentin M. Sluch et al.   Scientific Reports

Investigating human disease using stem cell models

(2014) Jared L. Sterneckert et al.   NATURE REVIEWS GENETICS

Chemically Induced Specification of Retinal Ganglion Cells From Human Embryonic and Induced Pluripotent Stem Cells

(2014) Hamidreza Riazifar et al.   Stem Cells Translational Medicine

Adult ciliary epithelial stem cells generate functional neurons and differentiate into both early and late born retinal neurons under non-cell autonomous influences

(2013) Carolina Del Debbio et al.   BMC NEUROSCIENCE

Enhanced optineurin E50K–TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma

(2013) Yuriko Minegishi et al.   HUMAN MOLECULAR GENETICS

Self-Formation of Optic Cups and Storable Stratified Neural Retina from Human ESCs

(2012) Tokushige Nakano et al.   Cell Stem Cell

Optic Vesicle-like Structures Derived from Human Pluripotent Stem Cells Facilitate a Customized Approach to Retinal Disease Treatment

(2011) Jason S. Meyer et al.   STEM CELLS

Neuronal transcriptional repressor REST suppresses an Atoh7-independent program for initiating retinal ganglion cell development

(2010) Chai-An Mao et al.   DEVELOPMENTAL BIOLOGY

Strategies for optic nerve rescue and regeneration in glaucoma and other optic neuropathies

(2010) A.H. Dahlmann-Noor et al.   DRUG DISCOVERY TODAY

Neuroprotection in glaucoma – Is there a future role?

(2010) Abeir Baltmr et al.   EXPERIMENTAL EYE RESEARCH

Generation, Purification and Transplantation of Photoreceptors Derived from Human Induced Pluripotent Stem Cells

(2010) Deepak A. Lamba et al.   PLoS One

Induced Pluripotent Stem Cells Generate Both Retinal Ganglion Cells and Photoreceptors: Therapeutic Implications in Degenerative Changes in Glaucoma and Age-Related Macular Degeneration

(2010) Sowmya Parameswaran et al.   STEM CELLS

Neuroprotection: Extrapolating from Neurologic Diseases to the Eye

(2009) Helen V. Danesh-Meyer et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Functional and Morphological Differences among Intrinsically Photosensitive Retinal Ganglion Cells

(2009) T. M. Schmidt et al.   JOURNAL OF NEUROSCIENCE

ROCK inhibition enhances the recovery and growth of cryopreserved human embryonic stem cells and human induced pluripotent stem cells

(2009) David A. Claassen et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Modeling early retinal development with human embryonic and induced pluripotent stem cells

(2009) J. S. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of the ontogeny of the vesicular glutamate transporter 3 (VGLUT3) with VGLUT1 and VGLUT2 in the rat retina

(2008) Salvatore L. Stella et al.   BRAIN RESEARCH

A Comprehensive Negative Regulatory Program Controlled by Brn3b to Ensure Ganglion Cell Specification from Multipotential Retinal Precursors

(2008) F. Qiu et al.   JOURNAL OF NEUROSCIENCE

Gene-regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2

(2008) X. Mu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA