Article
Spectroscopy
Arul Pundi, Chi-Jung Chang, Jemkun Chen, Shih-Rong Hsieh, Ming-Ching Lee
Summary: The development of fluorescence molecules for the detection of L-tryptophan has attracted attention, and a chiral sensor SDPA was synthesized. It showed fluorescence quenching by Fe3+ and Cu2+ and could detect L-tryptophan and L-cysteine at trace levels by turn-on fluorescence.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Inorganic & Nuclear
Yunxiao Ma, Mingchang Zhu, Ying Zhang, Enjun Gao, Shuangyan Wu
Summary: In this study, a novel self-calibrated luminescent sensor was developed for the detection of L-tryptophan (Trp) in plasma. The sensor exhibited excellent sensitivity, selectivity, rapid response time, and low detection limit. The mechanism of luminescence was mainly attributed to the energy transfer between Trp and the ligand, Sm3+ ions. Satisfactory recovery rates were obtained in plasma, indicating the potential application of the sensor for Trp detection.
INORGANICA CHIMICA ACTA
(2022)
Article
Agricultural Engineering
Amanda Ferreira dos Santos, Francisca Kamila Amancio Frutuoso, Clara de Amorim de Carvalho, Vitor Nairo Sousa Aguiar Lira, Antonio Ricardo Mendes Barros, Andre Bezerra dos Santos
Summary: This study evaluated the influence of carbon sources on the biosynthesis of alginate-like exopolymers (ALE) and tryptophan (Trp) in aerobic granular sludge (AGS). Acetate proved to be the best substrate for producing both ALE and Trp, while propionate and glycerol also showed potential. Glucose yielded the poorest results compared to other substrates.
BIORESOURCE TECHNOLOGY
(2022)
Review
Biotechnology & Applied Microbiology
Xin-Xin Liu, Bin Zhang, Lian-Zhong Ai
Summary: 5-hydroxytryptophan (5-HTP) plays a crucial role in regulating various physiological functions and is used in treating depression, insomnia, and other diseases. Due to inadequate natural extraction methods, increasing production efficiency through enzyme directed evolution and substrate supply pathways has become necessary to meet market demands.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Environmental Sciences
Dan Zhang, Shengke Yang, Chunyan Yang, Yangyang Chen, Ruixin Hu, Yali Xie, Yanhua Wang, Wenke Wang
Summary: Dissolved organic matter (DOM) plays a crucial role in the environmental behavior of antibiotics. This study investigated the interactions between two antibiotics and representative DOM components using multispectral techniques and DFT calculations. The results showed strong binding interactions between certain DOM components and coexistence antibiotics, providing important insights into the behavior of antibiotics in the environment.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biochemistry & Molecular Biology
Vasily A. Shenshin, Camille Lescanne, Guillaume Gines, Yannick Rondelez
Summary: This paper introduces a general strategy to interface DNA-based circuits with non-DNA signals through input-translating modules, allowing the construction of sensing circuits with good specificity and sensitivity. The programmability of the DNA layer enables signal processing operations such as logical inversion, signal modulation, and classification tasks.
NUCLEIC ACIDS RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Krystian Galecki, Agnieszka Kowalska-Baron, Katarzyna E. Nowak, Anna Gajda, Beata Kolesinska
Summary: This study demonstrates the utility of time-resolved fluorescence spectroscopy in detecting subtle changes in the microenvironment of tryptophan chromophore in AOT reverse micelles. The results show evident changes in spectral characteristics and fluorescence decay kinetics when tryptophan and its peptides are inserted into micelles.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Editorial Material
Biochemistry & Molecular Biology
Yoav S. Arava, Oded Beja
Summary: A new environmental study has found marine phages with deoxyuridine in their DNA instead of deoxythymidine, which are phylogenetically distinct from any currently known double-stranded DNA phages.
Article
Biochemistry & Molecular Biology
Jael R. Neyra Recky, M. Laura Dantola, Carolina Lorente
Summary: This study aims to evaluate the effect of adding DOPA on the oxidation process of biomolecules in acidic aqueous solutions. The results suggest that DOPA can decrease the consumption rate of biomolecules, possibly through electron transfer reactions between DOPA and biomolecule radicals.
PHOTOCHEMISTRY AND PHOTOBIOLOGY
(2023)
Article
Chemistry, Physical
Sourav Poddar, Jasmina Khanam
Summary: The present investigation focuses on the recovery of l-tryptophan from a dilute aqueous solution using extraction methods. The optimized procedure considers factors such as extractant, surfactant, initial pH, and flow rate of nitrogen gas. Response surface methodology and design models were used to assess the recovery and enrichment of the amino acid.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Multidisciplinary Sciences
Tom Meyer, Dor Shimon, Sawsan Youssef, Gal Yankovitz, Adi Tessler, Tom Chernobylsky, Anat Gaoni-Yogev, Rita Perelroizen, Noga Budick-Harmelin, Lawrence Steinman, Lior Mayo
Summary: This study reveals that NAD(+) generation via the salvage pathway regulates immune function of astrocytes. CD38, as the main NADase, is up-regulated in reactive astrocytes in models of neuroinflammation and MS. Inhibition of CD38 activity increases NAD(+) levels, suppresses proinflammatory transcriptional reprogramming, impairs chemotactic potential to inflammatory monocytes, and ameliorates EAE.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Chemistry, Multidisciplinary
Zhijun Wang, Yanlong Feng, Tiantian Song, Jie Su, Mengjie Fu, Haiying Lei
Summary: The study revealed that Zmcen and melittin bind in a 1:1 ratio to form a new complex, with melittin primarily binding to the C-terminus of Zmcen. Metal ions were found to have a promoting effect on the binding between Zmcen and melittin.
Article
Biophysics
Jiajia Liu, Yu Liu, Linghao Zhang, Shengnan Fu, Xin Su
Summary: A highly specific fluorescence assay for DNA modifying enzymes (DMEs) has been developed using dissipative DNA networks, enabling the distinction between target and non-target enzymes. This probe-based method exhibits excellent specificity and generality for various types of DMEs and provides a more reliable quantification mode based on area under curve.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Biophysics
Zackary A. Zimmers, Nicholas M. Adams, Frederick R. Haselton
Summary: A strategy combining target detection and no-target control reactions in the same tube using dual-chirality DNA amplification circuits is proposed. Experimental results show that the limit of detection of this dual-chirality design is similar to traditional designs, demonstrating its robustness and potential utility in biological samples.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Biochemistry & Molecular Biology
Abigaelle Pelletier, Eric Nelius, Zheng Fan, Ekaterina Khatchatourova, Abdiel Alvarado-Diaz, Jingyi He, Ewelina Krzywinska, Michal Sobecki, Shunmugam Nagarajan, Yann Kerdiles, Joachim Fandrey, Dagmar Gotthardt, Veronika Sexl, Katrien de Bock, Christian Stockmann
Summary: Natural killer (NK) cells exhibit different metabolic programs in resting and activated states, regulated by the oxygen-sensitive transcription factor HIF-1 alpha. In resting NK cells, HIF-1 alpha regulates tryptophan metabolism and cellular NAD(+) levels, preventing DNA damage and NK cell apoptosis. In activated NK cells under hypoxia, HIF-1 alpha drives glycolysis and enhances NK cell performance. These findings highlight the importance of HIF-1 alpha in regulating NK cell metabolism and function.
Article
Spectroscopy
Zh. E. Ozbekova, A. A. Abdyldaev, A. A. Kulmyrzaev
Summary: This study compared two drying methods for cow and yak muscles, finding that freeze drying caused less discoloration. Additionally, analysis of fluorescence spectra allowed for accurate prediction of chemical composition and color characteristics of the muscles.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Leo Mandic, Ivan Ljubic, Iva Dzeba
Summary: In this study, a combined experimental and computational approach was used to investigate the photoexcitation and photodegradation mechanisms of Doxazosin (DOX). The results provide valuable insights into the primary events following the photoexcitation of DOX and its potential applications.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiufeng Wang, Yao Jin, Wenhui Ai, Siqi Wang, Zhiqing Zhang, Ting Zhou, Fang Wang, Guodong Zhang
Summary: This study successfully synthesized near infrared fluorescence Ag2S quantum dots (QDs) and developed a dual-mode sensor for sulfide anion using the excellent oxidase-like characteristics of manganese dioxide (MnO2) nanosheets. The sensor showed a wider detection range, higher sensitivity, and shorter reaction time, making it suitable for highly selective detection of sulfide in different concentration ranges.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yafei Li, Yanming Ma, Chuantao Zheng, Di Yu, Lien Hu, Shuo Yang, Fang Song, Yadan Li, Shuanghai Liu, Zhanrui Zhang, Yu Zhang, Yiding Wang, Frank K. Tittel
Summary: To effectively monitor gas explosion and coal spontaneous combustion in coal mine, an intrinsically safe and explosion-proof dual-gas sensor system was developed for methane (CH4) and carbon monoxide (CO) measurement. The system achieved different measurement ranges using laser scanning and gas cells, and improved stability and accuracy through gas pre-treatment and temperature compensation algorithm.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Pei-Rong Chen, Li-Kang Chu
Summary: In this study, the hydrates of glyoxal were investigated using infrared absorption spectrometry. The results showed that at low concentrations, glyoxal mainly exists as monomeric dihydrate. These findings provide suitable detection windows for further research on the roles of glyoxal and its hydrates in atmospheric and aerosol chemistry, as well as the relevant reaction kinetics.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Nichole O'Neill, Thamires A. Lima, Fabio Furlan Ferreira, Nicolas J. Alvarez, Reinhard Schweitzer-Stenner
Summary: This study determines the main fibril axis of GHG gel-forming fibrils using various techniques and compares the results with simulated data. The analysis suggests that the hydrophobic xz-surfaces of GHG fibrils could be a good target for the adsorption of hydrophobic drugs.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Mengyuan Liu, Hanchuang Zhu, Yikun Fang, Caiyun Liu, Xinke Li, Xiaohui Zhang, Lixue Ma, Kun Wang, Miaohui Yu, Wenlong Sheng, Baocun Zhu
Summary: ABHS is an efficient fluorescent probe that can accurately and sensitively detect Al3+ with strong resistance to interference. It also demonstrates excellent detection and imaging capabilities in complex real samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Ahmed S. El-Shafie, Evana Rahman, Yasser Gadelhak, Rehab Mahmoud, Marwa El-Azary
Summary: The recycling of waste mandarin peels into biochar (MRBC) has been used as a high performance and cost-effective adsorbent for treating polluted wastewater effluents. Batch adsorption studies were conducted to analyze the adsorption competency of MRBC on two dyes, methylene blue (MB) and basic fuchsin (BF), either in individual solutions or binary combinations. The results showed that MRBC was capable of effectively removing a high percentage of both dyes. However, the adsorption capacity decreased when the dyes were combined. The cost estimation of MRBC production and wastewater treatment indicated that both were relatively low.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Anindita Bhatta, Jahnabi Upadhyaya, Dipak Chamlagai, Lincoln Dkhar, Pynskhemborlang T. Phanrang, Mohan Rao Kollipara, Sivaprasad Mitra
Summary: Derivatives of thiazole-pyrazole fused benzo-coumarin compounds were synthesized and their photophysical properties were investigated. The synthesized coumarin compounds showed potential as therapeutic agents for Alzheimer's disease, inhibiting acetylcholinesterase activity. The presence of human serum albumin was found to affect the inhibition activity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yongwei Duan, Quancheng Liu, Yiju Zhu, Qi Zhang, Xiaohui Duan, Hu Deng, Liping Shang
Summary: In this study, the phase transition of CL-20 was observed using terahertz spectroscopy, and quantum chemical calculations were employed to analyze the vibrations. The results indicated changes in the vibrations of CL-20 before and after phase transition.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yuefeng Gao, Sai Xu, Baojiu Chen
Summary: This study synthesized Cs2NaInCl6 nanocrystals co-doped with Sb3+ and Tb3+ ions as probes for copper ions detection in lubricating oil. The introduction of Sb3+ effectively reduced the band gap of the host material and enabled energy transfer pathway for Tb3+ emission. The doped Tb3+ ions resulted in the suppression of emission due to electron transfer. The Cs2NaInCl6: 2.5 %Sb3+, 40 %Tb3+ NCs exhibited superior sensitivity and selectivity for copper ions detection.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yu Liu, Yue Zhang, Changyao Liu, Ce Wang, Baocai Xu, Li Zhao
Summary: A highly sensitive detection platform for heparin was developed using a cationic fluorescent dye (cresyl violet acetate) as a fluorescence probe. The platform demonstrated high selectivity towards heparin and achieved detection in both HEPES solution and serum.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Lopamudra Roy, Nivedita Pan, Susmita Mondal, Ria Ghosh, Md. Nur Hasan, Neha Bhattacharyya, Soumendra Singh, Kallol Bhattacharyya, Arpita Chattopadhyay, Samir Kumar Pal
Summary: The study focuses on the interaction between reactive oxygen species (ROS) and a spectroscopic probe called Rose Bengal (RB), encapsulated in nanoscopic sodium dodecyl sulphate (SDS) micelles and entrapped in microscopic nylon 66 solid matrix. The research demonstrates efficient interaction between ROS and RB-SDS, and investigates the mechanism of hydroxyl radicals generation. Based on these findings, a prototype device utilizing RB embedded in a nylon thin film for quantification of ROS in extracellular fluids and food materials was developed.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiaosong Sun, Qihao Cui, Wenyue Dong, Qian Duan, Teng Fei
Summary: Conjugated porous polymers (CPPs) are promising sensing materials and their application in aqueous media is limited. In this study, we synthesized CPPs with porous structure and prepared nanoparticles, enabling efficient photoluminescence sensing of nitroaromatic explosives in aqueous phase.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Maria Cristina Caggiani, Germana Barone, Paolo Mazzoleni
Summary: Raman spectroscopy is commonly used for studying glassy materials in cultural heritage, but it is more difficult to interpret the spectra and apply the technique with portable instruments. In contrast, diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) can be used in archaeometric investigations as it is portable and non-invasive. However, there is limited application of this technique to historical glasses. This exploratory work demonstrates the potential of DRIFTS, in combination with portable X-ray Fluorescence (pXRF) and EDS microanalyses, for studying the composition and alteration of glass samples in cultural heritage.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)