Giant Cellular Vacuoles Induced by Rare Earth Oxide Nanoparticles are Abnormally Enlarged Endo/Lysosomes and Promote mTOR-Dependent TFEB Nucleus Translocation

Protease 3C of hepatitis A virus induces vacuolization of lysosomal/endosomal organelles and caspase-independent cell death

(2015) Andrey V Shubin et al.   BMC CELL BIOLOGY

The autophagic response to polystyrene nanoparticles is mediated by transcription factor EB and depends on surface charge

(2015) Wensi Song et al.   JOURNAL OF NANOBIOTECHNOLOGY

Innate Host Defense Requires TFEB-Mediated Transcription of Cytoprotective and Antimicrobial Genes

(2014) Orane Visvikis et al.   IMMUNITY

Effect of Silica Particle Size on Macrophage Inflammatory Responses

(2014) Toshimasa Kusaka et al.   PLoS One

What else is in store for autophagy? Exocytosis of autolysosomes as a mechanism of TFEB-mediated cellular clearance in Pompe disease

(2013) Erin J. Feeney et al.   Autophagy

Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha-1-anti-trypsin deficiency

(2013) Nunzia Pastore et al.   EMBO Molecular Medicine

A RANKL-PKC -TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts

(2013) M. Ferron et al.   GENES & DEVELOPMENT

Selective Cytotoxicity Effect of Cerium Oxide Nanoparticles Under UV Irradiation

(2013) Li Zhang et al.   Journal of Biomedical Nanotechnology

Gold nanostars for superficial diseases: a promising tool for localized hyperthermia?

(2013) Giuseppe Chirico et al.   Nanomedicine

Dynamic development of the protein corona on silica nanoparticles: composition and role in toxicity

(2013) Ninell P. Mortensen et al.   Nanoscale

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

(2013) Carmine Settembre et al.   NATURE CELL BIOLOGY

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

(2012) Carmine Settembre et al.   EMBO JOURNAL

Action of polystyrene nanoparticles of different sizes on lysosomal function and integrity

(2012) Eleonore Fröhlich et al.   Particle and Fibre Toxicology

Gold Nanoparticles Induce Autophagosome Accumulation through Size-Dependent Nanoparticle Uptake and Lysosome Impairment

(2011) Xiaowei Ma et al.   ACS Nano

TFEB, a novel mTORC1 effector implicated in lysosome biogenesis, endocytosis and autophagy

(2011) Samuel Peña-Llopis et al.   CELL CYCLE

Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways

(2011) Michela Palmieri et al.   HUMAN MOLECULAR GENETICS

Mechanisms of cellular adaptation to quantum dots – the role of glutathione and transcription factor EB

(2011) Kevin D. Neibert et al.   Nanotoxicology

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Time Evolution of the Nanoparticle Protein Corona

(2010) Eudald Casals et al.   ACS Nano

Rare earth oxide nanocrystals as a new class of autophagy inducers

(2010) Na Man et al.   Autophagy

Methamphetamine induces macropinocytosis in differentiated SH-SY5Y human neuroblastoma cells

(2010) Akina Nara et al.   BRAIN RESEARCH

Nano rare-earth oxides induced size-dependent vacuolization: an independent pathway from autophagy

(2010) Ying Zhang   International Journal of Nanomedicine

Neutral red uptake assay for the estimation of cell viability/cytotoxicity

(2008) Guillermo Repetto et al.   Nature Protocols

Cytoplasmic vacuolization responses to cytopathic bovine viral diarrhoea virus

(2007) Alexander V. Birk et al.   VIRUS RESEARCH