Continuous Production of Discrete Plasmid DNA-Polycation Nanoparticles Using Flash Nanocomplexation

Acidity-responsive gene delivery for “superfast” nuclear translocation and transfection with high efficiency

(2016) Jing-Yi Zhu et al.   BIOMATERIALS

Polymeric Nanoparticles for Nonviral Gene Therapy Extend Brain Tumor Survival in Vivo

(2015) Antonella Mangraviti et al.   ACS Nano

Hyperbranched–hyperbranched polymeric nanoassembly to mediate controllable co-delivery of siRNA and drug for synergistic tumor therapy

(2015) Hui-Zhen Jia et al.   JOURNAL OF CONTROLLED RELEASE

First-in-man Phase 1 Clinical Trial of Gene Therapy for Advanced Pancreatic Cancer: Safety, Biodistribution, and Preliminary Clinical Findings

(2015) Louis Buscail et al.   MOLECULAR THERAPY

Sugar-based amphiphilic nanoparticles arrest atherosclerosis in vivo

(2015) Daniel R. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly compacted biodegradable DNA nanoparticles capable of overcoming the mucus barrier for inhaled lung gene therapy

(2015) Panagiotis Mastorakos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultra-High Throughput Synthesis of Nanoparticles with Homogeneous Size Distribution Using a Coaxial Turbulent Jet Mixer

(2014) Jong-Min Lim et al.   ACS Nano

Flash Nanoprecipitation: Prediction and Enhancement of Particle Stability via Drug Structure

(2014) Zhengxi Zhu   MOLECULAR PHARMACEUTICS

Direct Interrogation of DNA Content Distribution in Nanoparticles by a Novel Microfluidics-Based Single-Particle Analysis

(2014) Cyrus W. Beh et al.   NANO LETTERS

Non-viral vectors for gene-based therapy

(2014) Hao Yin et al.   NATURE REVIEWS GENETICS

Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology

(2013) Nicolas Bertrand et al.   ADVANCED DRUG DELIVERY REVIEWS

Toroidal structures from brush amphiphiles

(2013) Hanying Luo et al.   CHEMICAL COMMUNICATIONS

Optimization of cell receptor-specific targeting through multivalent surface decoration of polymeric nanocarriers

(2013) Suzanne M. D'Addio et al.   JOURNAL OF CONTROLLED RELEASE

Gene therapy clinical trials worldwide to 2012 - an update

(2013) Samantha L. Ginn et al.   JOURNAL OF GENE MEDICINE

Kinetically Arrested Assemblies of Architecturally Distinct Block Copolymers

(2013) José Luis Santos et al.   MACROMOLECULES

Strategies for advancing cancer nanomedicine

(2013) Vikash P. Chauhan et al.   NATURE MATERIALS

Stimuli-responsive nanocarriers for drug delivery

(2013) Simona Mura et al.   NATURE MATERIALS

A nanoparticle formulation that selectively transfects metastatic tumors in mice

(2013) Jian Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

(2012) Nazila Kamaly et al.   CHEMICAL SOCIETY REVIEWS

Novel polyethylenimine-derived nanoparticles forin vivogene delivery

(2012) Soma Patnaik et al.   Expert Opinion on Drug Delivery

Effects of block copolymer properties on nanocarrier protection from in vivo clearance

(2012) Suzanne M. D'Addio et al.   JOURNAL OF CONTROLLED RELEASE

A simple confined impingement jets mixer for flash nanoprecipitation

(2012) Jing Han et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

High throughput production of single core double emulsions in a parallelized microfluidic device

(2012) Mark B. Romanowsky et al.   LAB ON A CHIP

Microfluidic technologies for accelerating the clinical translation of nanoparticles

(2012) Pedro M. Valencia et al.   Nature Nanotechnology

Controlling drug nanoparticle formation by rapid precipitation

(2011) Suzanne M. D'Addio et al.   ADVANCED DRUG DELIVERY REVIEWS

Self-assembling process of flash nanoprecipitation in a multi-inlet vortex mixer to produce drug-loaded polymeric nanoparticles

(2011) Hao Shen et al.   JOURNAL OF NANOPARTICLE RESEARCH

Tuning Physical Properties of Nanocomplexes through Microfluidics-Assisted Confinement

(2011) Yi-Ping Ho et al.   NANO LETTERS

Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy

(2010) N. Kolishetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Degradable polyethylenimines as DNA and small interfering RNA carriers

(2009) D Jere et al.   Expert Opinion on Drug Delivery

Translational nanomedicine: status assessment and opportunities

(2009) James S. Murday et al.   Nanomedicine-Nanotechnology Biology and Medicine

Preparation of Poly(ethylene glycol) Protected Nanoparticles with Variable Bioconjugate Ligand Density

(2008) Marian E. Gindy et al.   BIOMACROMOLECULES

Systemic Delivery of DNA or siRNA Mediated by Linear Polyethylenimine (L-PEI) Does Not Induce an Inflammatory Response

(2008) Marie-Elise Bonnet et al.   PHARMACEUTICAL RESEARCH