Nigral dopaminergic PAK4 prevents neurodegeneration in rat models of Parkinsons disease

TRPV1 on astrocytes rescues nigral dopamine neurons in Parkinson’s disease via CNTF

(2015) Jin H. Nam et al.   BRAIN

Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain

(2015) Laura Civiero et al.   JOURNAL OF NEUROCHEMISTRY

PGC-1α activity in nigral dopamine neurons determines vulnerability to α-synuclein

(2015) Carine Ciron et al.   Acta Neuropathologica Communications

p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-κB pathway

(2015) Nikhil Tyagi et al.   Oncotarget

Ageing and Parkinson's disease: Why is advancing age the biggest risk factor?

(2014) Amy Reeve et al.   AGEING RESEARCH REVIEWS

Region-Specific Activation of CRTC1-CREB Signaling Mediates Long-Term Fear Memory

(2014) Mio Nonaka et al.   NEURON

Regulation of tyrosine hydroxylase transcription by hnRNP K and DNA secondary structure

(2014) Kasturi Banerjee et al.   Nature Communications

The CRTC1-SIK1 Pathway Regulates Entrainment of the Circadian Clock

(2013) Aarti Jagannath et al.   CELL

Interleukin-13/Interleukin-4-induced oxidative stress contributes to death of prothrombinkringle-2 (pKr-2)-activated microglia

(2013) So-Yoon Won et al.   JOURNAL OF NEUROIMMUNOLOGY

 -Amyloid Disrupts Activity-Dependent Gene Transcription Required for Memory through the CREB Coactivator CRTC1

(2013) J. Espana et al.   JOURNAL OF NEUROSCIENCE

Parkinson's Disease Gene Therapy: Success by Design Meets Failure by Efficacy

(2013) Raymond T Bartus et al.   MOLECULAR THERAPY

TFEB-mediated autophagy rescues midbrain dopamine neurons from  -synuclein toxicity

(2013) M. Decressac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486

(2013) B. M. Dolan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletion of CREB-Regulated Transcription Coactivator 1 Induces Pathological Aggression, Depression-Related Behaviors, and Neuroplasticity Genes Dysregulation in Mice

(2012) Lionel Breuillaud et al.   BIOLOGICAL PSYCHIATRY

Activity-Dependent Transport of the Transcriptional Coactivator CRTC1 from Synapse to Nucleus

(2012) Toh Hean Ch'ng et al.   CELL

Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease

(2012) Rajnish Kumar Chaturvedi et al.   HUMAN MOLECULAR GENETICS

p21-Activated kinase 4 promotes prostate cancer progression through CREB

(2012) M-H Park et al.   ONCOGENE

PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease

(2011) Joo-Ho Shin et al.   CELL

Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway

(2011) Hyunkyung Jeong et al.   NATURE MEDICINE

Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates

(2011) Timothy J. Collier et al.   NATURE REVIEWS NEUROSCIENCE

SIK2 Is a Key Regulator for Neuronal Survival after Ischemia via TORC1-CREB

(2011) Tsutomu Sasaki et al.   NEURON

Clinical progression in Parkinson disease and the neurobiology of axons

(2010) Hsiao-Chun Cheng et al.   ANNALS OF NEUROLOGY

Overexpression of α-Synuclein Down-Regulates BDNF Expression

(2010) Yuhe Yuan et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

A Lentiviral Strategy for Highly Efficient Retrograde Gene Transfer by Pseudotyping with Fusion Envelope Glycoprotein

(2010) Shigeki Kato et al.   HUMAN GENE THERAPY

Striatal microRNA controls cocaine intake through CREB signalling

(2010) Jonathan A. Hollander et al.   NATURE

p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients

(2010) M. K. Y. Siu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RTP801 Is Induced in Parkinson's Disease and Mediates Neuron Death by Inhibiting Akt Phosphorylation/Activation

(2009) C. Malagelada et al.   JOURNAL OF NEUROSCIENCE

A tale of two Paks

(2008) Luis E. Arias-Romero et al.   BIOLOGY OF THE CELL

Targeted disruption of the Pak5 and Pak6 genes in mice leads to deficits in learning and locomotion

(2008) Tanya Nekrasova et al.   DEVELOPMENTAL BIOLOGY

Intra-axonal translation and retrograde trafficking of CREB promotes neuronal survival

(2008) Llewellyn J. Cox et al.   NATURE CELL BIOLOGY

Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis

(2008) Claire Henchcliffe et al.   Nature clinical practice. Neurology