Identification of Fic-1 as an enzyme that inhibits bacterial DNA replication by AMPylating GyrB, promoting filament formation

A Novel Link between Fic (Filamentation Induced by cAMP)-mediated Adenylylation/AMPylation and the Unfolded Protein Response

(2015) Anwesha Sanyal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology

(2015) Alexander Harms et al.   Cell Reports

Bacterial differentiation, development, and disease: mechanisms for survival

(2014) Sheryl S. Justice et al.   FEMS MICROBIOLOGY LETTERS

Unfolded Protein Response-regulatedDrosophilaFic (dFic) Protein Reversibly AMPylates BiP Chaperone during Endoplasmic Reticulum Homeostasis

(2014) Hyeilin Ham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Doc Toxin Is a Kinase That Inactivates Elongation Factor Tu

(2014) Jonathan W. Cruz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The many faces of Fic: structural and functional aspects of Fic enzymes

(2014) Abel Garcia-Pino et al.   TRENDS IN BIOCHEMICAL SCIENCES

A DNA Damage-Induced, SOS-Independent Checkpoint Regulates Cell Division in Caulobacter crescentus

(2014) Joshua W. Modell et al.   PLOS BIOLOGY

Teaching Fido New ModiFICation Tricks

(2014) Jonathan W. Cruz et al.   PLoS Pathogens

Uropathogenic Escherichia coli virulence and innate immune responses during urinary tract infection

(2013) Glen C Ulett et al.   CURRENT OPINION IN MICROBIOLOGY

Filamentous morphology of bacteria delays the timing of phagosome morphogenesis in macrophages

(2013) Akriti Prashar et al.   JOURNAL OF CELL BIOLOGY

A Bacterial Toxin Inhibits DNA Replication Elongation through a Direct Interaction with the β Sliding Clamp

(2013) Christopher D. Aakre et al.   MOLECULAR CELL

The Fic protein Doc uses an inverted substrate to phosphorylate and inactivate EF-Tu

(2013) Daniel Castro-Roa et al.   Nature Chemical Biology

SulA Inhibits Assembly of FtsZ by a Simple Sequestration Mechanism

(2012) Yaodong Chen et al.   BIOCHEMISTRY

Mechanism of invasion of lung epithelial cells by filamentousLegionella pneumophila

(2012) Akriti Prashar et al.   CELLULAR MICROBIOLOGY

Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins

(2012) Philipp Engel et al.   NATURE

A Xanthomonas uridine 5′-monophosphate transferase inhibits plant immune kinases

(2012) Feng Feng et al.   NATURE

Visual neurotransmission in Drosophila requires expression of Fic in glial capitate projections

(2012) Mokhlasur Rahman et al.   NATURE NEUROSCIENCE

Structural basis for substrate recognition by a unique Legionella phosphoinositide phosphatase

(2012) F. Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New(s) to the (Z-)ring

(2011) Clare L Kirkpatrick et al.   CURRENT OPINION IN MICROBIOLOGY

SulA-induced filamentation in Salmonella enterica serovar Typhimurium: effects on SPI-1 expression and epithelial infection

(2011) S. Humphrey et al.   JOURNAL OF APPLIED MICROBIOLOGY

Physics of Bacterial Morphogenesis

(2011) S. X. Sun et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Legionella pneumophila SidD is a deAMPylase that modifies Rab1

(2011) Yunhao Tan et al.   NATURE

Modulation of Rab GTPase function by a protein phosphocholine transferase

(2011) Shaeri Mukherjee et al.   NATURE

Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination

(2011) Y. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De-AMPylation of the Small GTPase Rab1 by the Pathogen Legionella pneumophila

(2011) M. R. Neunuebel et al.   SCIENCE

Persister Cells

(2010) Kim Lewis   Annual Review of Microbiology

Morphological plasticity promotes resistance to phagocyte killing of uropathogenic Escherichia coli

(2010) Dennis J. Horvath et al.   MICROBES AND INFECTION

The Legionella Effector Protein DrrA AMPylates the Membrane Traffic Regulator Rab1b

(2010) M. P. Muller et al.   SCIENCE

Inhibition of Host Vacuolar H+-ATPase Activity by a Legionella pneumophila Effector

(2010) Li Xu et al.   PLoS Pathogens

The Fic Domain: Regulation of Cell Signaling by Adenylylation

(2009) Carolyn A. Worby et al.   MOLECULAR CELL

Fido, a Novel AMPylation Domain Common to Fic, Doc, and AvrB

(2009) Lisa N. Kinch et al.   PLoS One

Morphological plasticity as a bacterial survival strategy

(2007) Sheryl S. Justice et al.   NATURE REVIEWS MICROBIOLOGY