Article
Medicine, General & Internal
Choong-Kyun Noh, Eunyoung Lee, Gil Ho Lee, Joon Koo Kang, Sun Gyo Lim, Bumhee Park, Jae Bum Park, Sung Jae Shin, Jae Youn Cheong, Jin Hong Kim, Kee Myung Lee
Summary: The study found that the monthly number of endoscopic examinations increased toward the end of the year, but the gastric cancer detection rates were negatively associated with calendar month. This highlights the importance of policy guidelines to improve cancer screening programs.
Article
Oncology
Yingshuang Zhu, Yanqin Huang, Yeting Hu, Yimin Fang, Xiangxing Kong, Qian Xiao, Jinjie He, Yunfeng Zhu, Qilong Li, Jinhuan Yang, Qi Dong, Mingjuan Jin, Meilin Wang, Kun Chen, Shu Zheng, Kefeng Ding
Summary: This study found that individuals with high-risk adenomas (at least one advanced adenoma or >= 3 nonadvanced adenomas) have an increased risk of subsequent CRC in the Chinese population, while those with 1 to 2 nonadvanced adenomas do not show significantly increased risk of CRC. These results provide valuable evidence for the current surveillance guidelines in China.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Article
Gastroenterology & Hepatology
Tonya Kaltenbach, Andrew Gawron, Craig S. Meyer, Samir Gupta, Amandeep Shergill, Jason A. Dominitz, Roy M. Soetikno, Tiffany Nguyen-Vu, Mary A. Whooley, Charles J. Kahi
Summary: The study showed that assessing adenoma detection rate (ADR) for colonoscopies irrespective of indication may be as effective as conventional ADR based on screening colonoscopies. This could facilitate quality monitoring and implementation of quality measurement and reporting. Future studies should further evaluate the validity of using overall ADR for quality reporting before adopting this method in clinical practice.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Gastroenterology & Hepatology
Uri Ladabaum, John Shepard, Ajitha Mannalithara
Summary: The study analyzed colonoscopy volumes and lesion detection rates before and after the endorsement of colorectal cancer (CRC) screening at 45-49 years of age. It found that lowering the screening initiation age had a modest effect on colonoscopy volume without compromising screening yield, and the detection rates for lesions in the 45-49 age group were similar to those in older age groups. Further national monitoring is needed to fully assess the impact of this change in screening guidelines.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Editorial Material
Oncology
David Lieberman
Summary: There is solid evidence supporting the effectiveness of colorectal cancer screening in reducing incidence and mortality. Guidelines suggest screening for individuals between 45 to 75 years old, but there is uncertainty regarding the benefits for those above 75 years old. Dalmat et al. found that individuals who had a negative colonoscopy more than 10 years prior to reaching 76 to 85 years old had a lower risk of colorectal cancer and may not benefit from further screening. It is important to consider the study population did not include individuals with a family history of colon cancer or high-risk adenomas.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Article
Medicine, General & Internal
Erica K. Barnell, Elizabeth M. Wurtzler, Julie La Rocca, Thomas Fitzgerald, Jessica Petrone, Yansheng Hao, Yiming Kang, Faith L. Holmes, David A. Lieberman
Summary: This study evaluated the sensitivity and specificity of a noninvasive multitarget stool RNA test for colorectal cancer and precancerous lesions. The results showed that the test had a sensitivity of 94% for detecting colorectal cancer and 46% for detecting advanced adenomas, with a specificity of 88%.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Review
Oncology
Edward Young, Louisa Edwards, Rajvinder Singh
Summary: Artificial intelligence (AI) systems have become increasingly available in the field of endoscopy, particularly in colonoscopy. This comprehensive review focuses on the application of AI in detecting and characterizing colorectal polyps, with the goal of improving the efficacy of colorectal cancer screening and prevention. AI-driven algorithms show potential in addressing the challenge of overlooked polyps and empowering gastroenterologists to accurately characterize polyps without extensive training in advanced mucosal imaging. By integrating AI technologies into routine colonoscopy, the detection and characterization of polyps can be advanced, potentially leading to more effective colorectal cancer screening and prevention.
Article
Medicine, General & Internal
Kazuhiro Mizukami, Erina Fushimi, Ryota Sagami, Takashi Abe, Takao Sato, Shohei Terashi, Masahide Fukuda, Hidefumi Nishikiori, Takayuki Nagai, Masaaki Kodama, Kazunari Murakami
Summary: This study investigated the lesion-detection ability of an AI-equipped colonoscopy as an addition to colonoscopy screening. The results showed that the CADe group had a significantly higher adenoma detection rate compared to the conventional group, especially for non-expert endoscopists.
JOURNAL OF CLINICAL MEDICINE
(2023)
Editorial Material
Gastroenterology & Hepatology
Chelsea Hayman, Dinesh Vyas
Summary: Colorectal cancer is the second leading cause of mortality in the United States, with an increasing number of patients diagnosed at advanced stages before the age of 50, requiring earlier screening. Water insufflation colonoscopies have shown promising results in reducing the need for sedation, decreasing discomfort, and increasing visibility of the colonic mucosa, potentially increasing the number of proficient endoscopists in training to serve the aging population.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Surgery
Ipek Sapci, Xue Jia, James Wu, Emre Gorgun, David Liska, James Church, Scott R. Steele, Michael A. Valente
Summary: The time of day does not have a significant effect on the quality metrics of colonoscopy in patients undergoing screening. In our practice, colonoscopies meet and exceed all national quality benchmarks, regardless of the time of day they are performed.
AMERICAN JOURNAL OF SURGERY
(2022)
Article
Oncology
Deborah A. Fisher, Leila Saoud, Kristen Hassmiller Lich, A. Mark Fendrick, A. Burak Ozbay, Bijan J. Borah, Michael Matney, Marcus Parton, Paul J. Limburg
Summary: The study found that assuming different adenoma sensitivities for screening and follow-up/surveillance colonoscopies can impact the potential benefits of stool-based screening strategies.
Review
Gastroenterology & Hepatology
Sunil Samnani, Rishad Khan, Steven J. Heitman, Robert J. Hilsden, Michael F. Byrne, Samir C. Grover, Nauzer Forbes
Summary: Screening-related colonoscopy is crucial for diagnosing and preventing colorectal cancer. This review summarizes the available evidence on strategies and techniques to improve adenoma detection rates. The importance of colonoscopy quality indicators is emphasized given the high prevalence and impact of colorectal cancer.
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY
(2023)
Article
Surgery
Claudia Jaensch, Mogens Harrits Jepsen, David Hoyrup Christiansen, Anders Husted Madsen, Mogens Rorbaek Madsen
Summary: The use of Endocuff Vision did not significantly affect ADR compared to standard colonoscopy, but more serrated lesions were detected in the Endocuff group.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Biochemistry & Molecular Biology
Francesca Privitera, Rossella Gioco, Alba Ilari Civit, Daniela Corona, Simone Cremona, Lidia Puzzo, Salvatore Costa, Giuseppe Trama, Flavia Mauceri, Aurelio Cardella, Giuseppe Sangiorgio, Riccardo Nania, Pierfrancesco Veroux, Massimiliano Veroux
Summary: Kidney transplant recipients do not have an increased risk of developing colorectal cancer compared to the healthy population, but they have a higher risk of developing colorectal adenomas.
Article
Gastroenterology & Hepatology
Sergei Vosko, Neal Shahidi, Mayenaaz Sidhu, W. Arnout van Hattem, Iddo Bar-Yishay, Scott Schoeman, David J. Tate, Luke F. Hourigan, Rajvinder Singh, Alan Moss, Karen Byth, Eric Y. T. Lee, Nicholas G. Burgess, Michael J. Bourke
Summary: This study found significant differences in optical evaluation performance between flat and nodular large nonpedunculated colorectal polyps. Flat lesions can be presumed benign and managed accordingly, while nodular lesions are more likely to be missed for submucosal invasive cancer.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Jun-young Kim, Joel Cramer, Kyujoon Lee, Dong-Soo Han, Dongwook Go, Pavel Salev, Pavel N. Lapa, Nicolas M. Vargas, Ivan K. Schuller, Yuriy Mokrousov, Gerhard Jakob, Mathias Klaeui
Summary: This study investigates current-induced spin-orbit torques in VO2/NiFe heterostructures and reveals that the change in spin absorption across the VO2 phase transition leads to a twofold increase in the Gilbert damping parameter alpha with temperature. Furthermore, a significant modulation and sign change of the current-induced spin-orbit torque across the VO2 phase transition suggest the existence of two competing spin-orbit torque generating mechanisms.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Gastroenterology & Hepatology
Seung Wook Hong, Byong Duk Ye, Jae Hee Cheon, Ji Hyun Lee, Ja Seol Koo, Byung Ik Jang, Kang-Moon Lee, You Sun Kim, Tae Oh Kim, Jong Pil Im, Geun Am Song, Sung-Ae Jung, Hyun Soo Kim, Dong Il Park, Hyun-Soo Kim, Kyu Chan Huh, Young-Ho Kim, Jae Myung Cha, Geom Seog Seo, Chang Hwan Choi, Hyun Joo Song, Gwang Ho Baik, Ji Won Kim, Sung Jae Shin, Young Sook Park, Chang Kyun Lee, Jun Lee, Sung Hee Jung, Yunho Jung, Sung Chul Park, Young-Eun Joo, Yoon Tae Jeen, Dong Soo Han, Suk-Kyun Yang, Hyo Jong Kim, Won Ho Kim, Joo Sung Kim
Article
Gastroenterology & Hepatology
Hee Seung Hong, Jiwon Baek, Jae Chul Park, Ho-Su Lee, Dohoon Park, A-Ran Yoon, Soo Jung Park, Sung Noh Hong, Seong-Joon Koh, Chang Kyun Lee, Bo-In Lee, Sung Wook Hwang, Sang Hyoung Park, Seung-Jae Myung, Suk-Kyun Yang, Kyuyoung Song, Byong Duk Ye
Summary: This study investigated the clinical and genetic characteristics of Korean patients with CEAS. Out of 46 patients, 14 were genetically confirmed to have CEAS. The median age at diagnosis was 44.5 years and most patients were females. Abdominal pain, anemia, and hypoalbuminemia were common symptoms. The most commonly involved site was the ileum, and some patients exhibited manifestations of primary hypertrophic osteoarthropathy.
Article
Biochemistry & Molecular Biology
Jae Gon Lee, Jiyoung Lee, A-reum Lee, Su Vin Jo, Chan Hyuk Park, Dong Soo Han, Chang Soo Eun
Summary: Supplementation of SCFAs did not lead to a significant reduction in colon inflammation, but it did increase the expression of regulatory T cells and IL-17-producing T cells, as well as promote both protective and aggressive gut microbiota.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2022)
Article
Nutrition & Dietetics
Jong-Wook Yoo, Yoon-Jung Shin, Xiaoyang Ma, Young-Hoo Son, Hyo-Min Jang, Chang Kyun Lee, Dong-Hyun Kim
Summary: Gut microbiota dysbiosis is closely related to psychiatric disorders and inflammatory bowel disease. The transplantation of Enterobacteriaceae-rich gut microbiota can cause depression and colitis in mice. However, treatment with anti-inflammatory probiotics can alleviate these symptoms.
Article
Nutrition & Dietetics
Sang Young Kim, Jung Hyun Kwak, Chang Soo Eun, Dong Soo Han, Yong Sung Kim, Kyu Sang Song, Bo Youl Choi, Hyun Ja Kim
Summary: Dietary factors, such as high meal frequency, overeating, and preference for spicy or salty foods, significantly increase the risk of gastric cancer.
Review
Gastroenterology & Hepatology
Soo-Young Na, Chang Hwan Choi, Eun Mi Song, Ki Bae Bang, Sang Hyoung Park, Eun Soo Kim, Jae Jun Park, Bora Keum, Chang Kyun Lee, Bo-In Lee, Seung-Bum Ryoo, Seong-Joon Koh, Miyoung Choi, Joo Sung Kim
Summary: Ulcerative colitis is a chronic inflammatory bowel disease with an uncertain and potentially severe natural course. The development of anti-tumor necrosis factor agents has expanded therapeutic options, including novel biologics and small molecules, which have shown potential efficacy and safety. However, questions remain regarding the optimal use of these drugs.
INTESTINAL RESEARCH
(2022)
Article
Gastroenterology & Hepatology
Seon-Young Park, Jun Kyu Lee, Chang-Hwan Park, Byung-Wook Kim, Chang Kyun Lee, Hong Jun Park, Byung Ik Jang, Dong Uk Kim, Jin Myung Park, Jae Min Lee, Young Sin Cho, Hyung Ku Chon, Seung Young Seo, Woo Hyun Paik
Summary: This study investigated the sedation practices of endoscopists in Korea in 2019 and compared them to those in 2014. The study found that respondents preferred propofol-based sedation and used oxygen supplementation and monitoring of oxygen saturation more frequently in 2019 compared to 2014.
Article
Nutrition & Dietetics
Sang Young Kim, Chang Soo Eun, Dong Soo Han, Yong Sung Kim, Kyu Sang Song, Bo Youl Choi, Hyun Ja Kim
Summary: This study found a significant association between high glycemic index and glycemic load and an increased risk of gastric cancer, especially among males, older individuals, smokers, drinkers, and people with Helicobacter pylori infection.
NUTRITION RESEARCH
(2022)
Article
Gastroenterology & Hepatology
Jae Hee Cheon, Hyun-Soo Kim, Dong Soo Han, Sung Kook Kim, Sung Jae Shin, Joo Sung Kim, Byong Duk Ye, Geun Am Song, YoungJa Lee, Youngdoe Kim, Yoosun Lee, Won Ho Kim
Summary: This study provides evidence that infliximab is effective and well-tolerated in patients with moderate-to-severe active intestinal Behcet's disease.
Article
Nutrition & Dietetics
Jung Hyun Kwak, Chang Soo Eun, Dong Soo Han, Yong Sung Kim, Kyu Sang Song, Bo Youl Choi, Hyun Ja Kim
Summary: This study evaluated the association of individual or a combination of protective foods on the incidence of gastric cancer in H. pylori-positive subjects. Results showed that a higher intake of soy products and fruits was associated with a lower risk of gastric cancer. Additionally, the combination of soy products or fruits with dairy products also reduced the risk of gastric cancer.
NUTRITION RESEARCH AND PRACTICE
(2023)
Editorial Material
Gastroenterology & Hepatology
Shin Ju Oh, Hyo Jong Kim, Chang Kyun Lee
Summary: This article is connected to the papers by Oh et al. Visit to view these papers.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
Shin Ju Oh, Hyo Jong Kim, Chang Kyun Lee, Korean Society Gastroenterology
Summary: This study aimed to investigate the association and dose-response relationships between antibiotic use and subsequent inflammatory bowel disease (IBD) risk in the Korean population. The findings revealed that antibiotic prescriptions 2-5 years prior to diagnosis significantly increased the odds of developing IBD, and early-life antibiotic exposure was linked with childhood-onset IBD risk. These findings establish antibiotic use as a significant risk factor for IBD across different environmental backgrounds.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Letter
Gastroenterology & Hepatology
Shin Ju Oh, Hyo Jong Kim, Chang Kyun Lee
Summary: This article is associated with the papers of Oh et al. To access and read these papers, please visit the provided link.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Acoustics
Myung-won You, Sung Kyoung Moon, Yong Dae Lee, Shin Ju Oh, Seong Jin Park, Chang Kyun Lee
Summary: This study aimed to analyze the correlation between intestinal ultrasound (IUS) and serum and fecal biomarkers, as well as the characteristics of small bowel disease, for the assessment of active bowel inflammation. The findings showed a significant correlation between disease activity determined by IUS and the biomarkers, with better predictive value for patients with active small bowel disease.
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
