Potential effect of ezetimibe againstMycobacterium tuberculosisinfection in type II diabetes

Statin, Calcium Channel Blocker and Beta Blocker Therapy May Decrease the Incidence of Tuberculosis Infection in Elderly Taiwanese Patients with Type 2 Diabetes

(2015) Mei-Yueh Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Novel Inhibitors of Cholesterol Degradation in Mycobacterium tuberculosis Reveal How the Bacterium’s Metabolism Is Constrained by the Intracellular Environment

(2015) Brian C. VanderVen et al.   PLoS Pathogens

Ezetimibe suppresses cholesterol accumulation in lipid-loaded vascular smooth muscle cells in vitro via MAPK signaling

(2014) Li Qin et al.   ACTA PHARMACOLOGICA SINICA

Diabetes and immunity to tuberculosis

(2014) Nuria Martinez et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The effects of statin use on the development of tuberculosis among patients with diabetes mellitus

(2014) Y. A. Kang et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

Simvastatin increases the in vivo activity of the first-line tuberculosis regimen

(2014) C. Skerry et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Diabetes and Risk of Tuberculosis Relapse: Nationwide Nested Case-Control Study

(2014) Pin-Hui Lee et al.   PLoS One

Methylcitrate cycle defines the bactericidal essentiality of isocitrate lyase for survival ofMycobacterium tuberculosison fatty acids

(2014) Hyungjin Eoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metformin as adjunct antituberculosis therapy

(2014) A. Singhal et al.   Science Translational Medicine

Host-pathogen interactions in tuberculosis patients with type 2 diabetes mellitus

(2014) Blanca I. Restrepo et al.   TUBERCULOSIS

Inhibition of Niemann-Pick-type C1-like1 by ezetimibe activates autophagy in human hepatocytes and reduces mutant α1-antitrypsin Z deposition

(2013) Takeshi Yamamura et al.   HEPATOLOGY

IntracellularMycobacterium tuberculosisExploits Host-derived Fatty Acids to Limit Metabolic Stress

(2013) Wonsik Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Statin Therapy Reduces the Mycobacterium tuberculosis Burden in Human Macrophages and in Mice by Enhancing Autophagy and Phagosome Maturation

(2013) Suraj P. Parihar et al.   JOURNAL OF INFECTIOUS DISEASES

The effect of simvastatin on lipid droplets accumulation in human embryonic kidney cells and pancreatic cancer cells

(2013) Helena Gbelcová et al.   Lipids in Health and Disease

Aminopeptidase N facilitates entry and intracellular survival ofMycobacterium tuberculosisin monocytes

(2013) Hsin-Tsung Ho et al.   RESPIROLOGY

Hypercholesterolemic LDL receptor-deficient mice mount a neutrophilic response to tuberculosis despite the timely expression of protective immunity

(2012) Gregory W. Martens et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Editorial: Lipids: fueling the fire in tuberculosis?

(2012) Vishwa Deep Dixit   JOURNAL OF LEUKOCYTE BIOLOGY

Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis

(2011) Hugues Ouellet et al.   TRENDS IN MICROBIOLOGY

Mycobacterium tuberculosis Uses Host Triacylglycerol to Accumulate Lipid Droplets and Acquires a Dormancy-Like Phenotype in Lipid-Loaded Macrophages

(2011) Jaiyanth Daniel et al.   PLoS Pathogens

Ezetimibe; More Than a Low Density Lipoprotein Cholesterol Lowering Drug? An Update After 4 Years

(2010) Eirini Lioudaki et al.   Current Vascular Pharmacology

Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism

(2010) Mi-Jeong Kim et al.   EMBO Molecular Medicine

Triacylglycerol Utilization Is Required for Regrowth of In Vitro Hypoxic Nonreplicating Mycobacterium bovis Bacillus Calmette-Guerin

(2009) K. L. Low et al.   JOURNAL OF BACTERIOLOGY

Mycobacterium tuberculosis Is Able To Accumulate and Utilize Cholesterol

(2009) A. Brzostek et al.   JOURNAL OF BACTERIOLOGY

Mycobacterium tuberculosis Rv3802c Encodes a Phospholipase/Thioesterase and Is Inhibited by the Antimycobacterial Agent Tetrahydrolipstatin

(2009) Sarah K. Parker et al.   PLoS One

Reduced Expression of ATP-Binding Cassette Transporter G1 Increases Cholesterol Accumulation in Macrophages of Patients With Type 2 Diabetes Mellitus

(2008) Jeremy P. Mauldin et al.   CIRCULATION

Hypercholesterolemia Impairs Immunity to Tuberculosis

(2008) G. W. Martens et al.   INFECTION AND IMMUNITY

Cholesterol Accumulation by Macrophages Impairs Phagosome Maturation

(2008) Kassidy K. Huynh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ezetimibe monotherapy for cholesterol lowering in 2,722 people: systematic review and meta-analysis of randomized controlled trials

(2008) A. Pandor et al.   JOURNAL OF INTERNAL MEDICINE

Simvastatin with or without Ezetimibe in Familial Hypercholesterolemia

(2008) John J.P. Kastelein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mycobacterial persistence requires the utilization of host cholesterol

(2008) A. K. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diabetes Mellitus Increases the Risk of Active Tuberculosis: A Systematic Review of 13 Observational Studies

(2008) Christie Y Jeon et al.   PLOS MEDICINE

Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence

(2008) Pascale Peyron et al.   PLoS Pathogens