Changes in cellular glycosylation of leukemia cells upon treatment with acridone derivatives yield insight into drug action

Exposure of CCRF-CEM cells to acridone derivative 8a triggers tumor death via multiple mechanisms

(2016) Yini Wang et al.   PROTEOMICS

A Method for In-Depth Structural Annotation of Human Serum Glycans That Yields Biological Variations

(2015) Ting Song et al.   ANALYTICAL CHEMISTRY

Acridone-based Antitumor Agents: A Mini-review

(2015) Wesam Alwan et al.   Anti-Cancer Agents in Medicinal Chemistry

Synthesis and antiproliferative activity of 2,7-diamino l0-(3,5-dimethoxy)benzyl-9(10H)-acridone derivatives as potent telomeric G-quadruplex DNA ligands

(2015) Chunmei Gao et al.   BIOORGANIC CHEMISTRY

Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds

(2015) Jana Janočková et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Characteristic Changes in Cell Surface Glycosylation Accompany Intestinal Epithelial Cell (IEC) Differentiation: High Mannose Structures Dominate the Cell Surface Glycome of Undifferentiated Enterocytes

(2015) Dayoung Park et al.   MOLECULAR & CELLULAR PROTEOMICS

Drug–DNA Interaction Studies of Acridone-Based Derivatives

(2015) Kuntebomanahalli Thimmaiah et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Discovering cancer biomarkers from clinical samples by protein microarrays

(2015) Bin Hu et al.   Proteomics Clinical Applications

In-Depth Method for the Characterization of Glycosylation in Manufactured Recombinant Monoclonal Antibody Drugs

(2014) Ting Song et al.   ANALYTICAL CHEMISTRY

Design and Synthesis of Quinazolinone Tagged Acridones as Cytotoxic Agents and Their Effects on EGFR Tyrosine Kinase

(2014) Yarlagadda Rajesh Babu et al.   ARCHIV DER PHARMAZIE

Recent advances in the understanding of biological implications and modulation methodologies of monoclonal antibody N-linked high mannose glycans

(2014) Helen H. Shi et al.   BIOTECHNOLOGY AND BIOENGINEERING

Evaluation of Glycomic Profiling as a Diagnostic Biomarker for Epithelial Ovarian Cancer

(2014) K. Kim et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Systems glycobiology for glycoengineering

(2014) Philipp N Spahn et al.   CURRENT OPINION IN BIOTECHNOLOGY

Lectin approaches for glycoproteomics in FDA-approved cancer biomarkers

(2014) Haitham A Badr et al.   Expert Review of Proteomics

Investigation of Drug–Model Cell Membrane Interactions Using Sum Frequency Generation Vibrational Spectroscopy: A Case Study of Chlorpromazine

(2014) Fu-Gen Wu et al.   Journal of Physical Chemistry C

Replication

(2014) Paul Blainey et al.   NATURE METHODS

Biophysics of cell membrane lipids in cancer drug resistance: Implications for drug transport and drug delivery with nanoparticles

(2013) Chiranjeevi Peetla et al.   ADVANCED DRUG DELIVERY REVIEWS

Isomer-specific chromatographic profiling yields highly sensitive and specific potential N-glycan biomarkers for epithelial ovarian cancer

(2013) Serenus Hua et al.   JOURNAL OF CHROMATOGRAPHY A

Developments in the Identification of Glycan Biomarkers for the Detection of Cancer

(2013) L. Renee Ruhaak et al.   MOLECULAR & CELLULAR PROTEOMICS

Acridone Derivative 8a Induces Oxidative Stress-Mediated Apoptosis in CCRF-CEM Leukemia Cells: Application of Metabolomics in Mechanistic Studies of Antitumor Agents

(2013) Yini Wang et al.   PLoS One

Interaction of nonsteroidal anti-inflammatory drugs with membranes: In vitro assessment and relevance for their biological actions

(2013) Catarina Pereira-Leite et al.   PROGRESS IN LIPID RESEARCH

The regulatory power of glycans and their binding partners in immunity

(2013) Jenny L. Johnson et al.   TRENDS IN IMMUNOLOGY

Mass spectrometry-based proteomics: existing capabilities and future directions

(2012) Thomas E. Angel et al.   CHEMICAL SOCIETY REVIEWS

5-AZA-2'-deoxycytidine induced demethylation influencesN-glycosylation of secreted glycoproteins in ovarian cancer

(2012) Radka Saldova et al.   Epigenetics

Comparison of the Human and Bovine Milk N-Glycome via High-Performance Microfluidic Chip Liquid Chromatography and Tandem Mass Spectrometry

(2012) Charles C. Nwosu et al.   JOURNAL OF PROTEOME RESEARCH

Annotation of a Serum N-Glycan Library for Rapid Identification of Structures

(2012) Danielle Aldredge et al.   JOURNAL OF PROTEOME RESEARCH

Vertebrate protein glycosylation: diversity, synthesis and function

(2012) Kelley W. Moremen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Characterization of disease-associatedN-linked glycoproteins

(2012) Yuan Tian et al.   PROTEOMICS

Comprehensive native glycan profiling with isomer separation and quantitation for the discovery of cancer biomarkers

(2011) Serenus Hua et al.   ANALYST

Site-specific protein glycosylation analysis with glycan isomer differentiation

(2011) Serenus Hua et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

N-Glycan Profiling of Dried Blood Spots

(2011) L. Renee Ruhaak et al.   ANALYTICAL CHEMISTRY

Inhibition of Junin virus RNA synthesis by an antiviral acridone derivative

(2011) Claudia S. Sepúlveda et al.   ANTIVIRAL RESEARCH

Mechanistic insights into protein precipitation by alcohol

(2011) Hiroki Yoshikawa et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The Antifungal Drug Itraconazole Inhibits Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Glycosylation, Trafficking, and Signaling in Endothelial Cells

(2011) Benjamin A. Nacev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

9-Acridone-4-carboxylic acid as an efficient Cr(III) fluorescent sensor: Trace level detection, estimation and speciation studies

(2011) Debasis Karak et al.   JOURNAL OF HAZARDOUS MATERIALS

Oligosaccharyltransferase: the central enzyme of N-linked protein glycosylation

(2011) Elisabeth Mohorko et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Identification of Glycan Structure Alterations on Cell Membrane Proteins in Desoxyepothilone B Resistant Leukemia Cells

(2011) Miyako Nakano et al.   MOLECULAR & CELLULAR PROTEOMICS

Extensive Determination of Glycan Heterogeneity Reveals an Unusual Abundance of High Mannose Glycans in Enriched Plasma Membranes of Human Embryonic Stem Cells

(2011) Hyun Joo An et al.   MOLECULAR & CELLULAR PROTEOMICS

Novel synthetic 2-amino-10-(3,5-dimethoxy)benzyl-9(10H)-acridinone derivatives as potent DNA-binding antiproliferative agents

(2010) Chunmei Gao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Human Serum Processing and Analysis Methods for Rapid and Reproducible N-Glycan Mass Profiling

(2010) Scott R. Kronewitter et al.   JOURNAL OF PROTEOME RESEARCH

Development of an Annotated Library of Neutral Human Milk Oligosaccharides

(2010) Shuai Wu et al.   JOURNAL OF PROTEOME RESEARCH

Annotation and Structural Analysis of Sialylated Human Milk Oligosaccharides

(2010) Shuai Wu et al.   JOURNAL OF PROTEOME RESEARCH

Determination of glycosylation sites and site-specific heterogeneity in glycoproteins

(2009) Hyun Joo An et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Differential expression of α-2,3-sialyltransferases and α-1,3/4-fucosyltransferases regulates the levels of sialyl Lewis a and sialyl Lewis x in gastrointestinal carcinoma cells

(2009) A.S. Carvalho et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Synthesis and potent antileukemic activities of 10-benzyl-9(10H)-acridinones

(2008) Chunmei Gao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Differentiating N-linked glycan structural isomers in metastatic and nonmetastatic tumor cells using sequential mass spectrometry

(2008) J. M. Prien et al.   GLYCOBIOLOGY

Mass spectrometric profiling of N-linked oligosaccharides and uncommon glycoform in mouse serum with head and neck tumor

(2008) Erika Lattová et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Ribophorin I regulates substrate delivery to the oligosaccharyltransferase core

(2008) C. M. Wilson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA