Drug penetration and metabolism in 3D cell cultures treated in a 3D printed fluidic device: assessment of irinotecan via MALDI imaging mass spectrometry

A Diffusion-Based and Dynamic 3D-Printed Device That Enables Parallel in Vitro Pharmacokinetic Profiling of Molecules

(2016) Sarah Y. Lockwood et al.   ANALYTICAL CHEMISTRY

Chemometric analysis of MALDI mass spectrometric images of three-dimensional cell culture systems

(2015) Eric M. Weaver et al.   Analytical Methods

Single Cell Metabolic Profiling of Tumor Mimics

(2013) Richard B. Keithley et al.   ANALYTICAL CHEMISTRY

Evaluation of Therapeutics in Three-Dimensional Cell Culture Systems by MALDI Imaging Mass Spectrometry

(2013) Xin Liu et al.   ANALYTICAL CHEMISTRY

A 3D Printed Fluidic Device that Enables Integrated Features

(2013) Kari B. Anderson et al.   ANALYTICAL CHEMISTRY

The use of bioreactors as in vitro models in pharmaceutical research

(2013) Maaria Ginai et al.   DRUG DISCOVERY TODAY

AlgiMatrix™ Based 3D Cell Culture System as an In-Vitro Tumor Model for Anticancer Studies

(2013) Chandraiah Godugu et al.   PLoS One

An oxygen-permeable spheroid culture system for the prevention of central hypoxia and necrosis of spheroids

(2012) Takahisa Anada et al.   BIOMATERIALS

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

(2012) Maria Vinci et al.   BMC BIOLOGY

Differences in growth properties of endometrial cancer in three dimensional (3D) culture and 2D cell monolayer

(2012) Kenny Chitcholtan et al.   EXPERIMENTAL CELL RESEARCH

Imaging Mass Spectrometry of Three-Dimensional Cell Culture Systems

(2011) Haohang Li et al.   ANALYTICAL CHEMISTRY

Treatment Decisions After Diagnosis of Metastatic Colorectal Cancer

(2011) Thomas H. Cartwright   Clinical Colorectal Cancer

Developments in three-dimensional cell culture technology aimed at improving the accuracy ofin vitroanalyses

(2010) Daniel J. Maltman et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Simple liquid chromatography method for the quantification of irinotecan and SN38 in sheep plasma: Application to in vivo pharmacokinetics after pulmonary artery chemoembolization using drug eluting beads

(2010) Minh-Tâm Baylatry et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Different responses in transformation of MDCK cells in 2D and 3D culture by v-Src as revealed by microarray techniques, RT-PCR and functional assays

(2010) Mira Töyli et al.   LABORATORY INVESTIGATION

In vitro pharmacodynamic models to determine the effect of antibacterial drugs

(2009) J. Gloede et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Perspectives for imaging mass spectrometry in the proteomics landscape

(2009) Luke MacAleese et al.   PROTEOMICS

Novel application of multicellular layers culture for in situ evaluation of cytotoxicity and penetration of paclitaxel

(2008) Ahmed Mohamed Al-Abd et al.   CANCER SCIENCE

Molecular imaging of proteins in tissues by mass spectrometry

(2008) E. H. Seeley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA