Function changing mutations in glucocorticoid receptor evolution correlate with their relevance to mode coupling

Dynamic Transmission of Protein Allostery without Structural Change: Spatial Pathways or Global Modes?

(2015) Tom C.B. McLeish et al.   BIOPHYSICAL JOURNAL

Structure-Encoded Global Motions and Their Role in Mediating Protein-Substrate Interactions

(2015) Ivet Bahar et al.   BIOPHYSICAL JOURNAL

A theoretical view of protein dynamics

(2014) Modesto Orozco   CHEMICAL SOCIETY REVIEWS

Glucocorticoid Receptor Modulators Informed by Crystallography Lead to a New Rationale for Receptor Selectivity, Function, and Implications for Structure-Based Design

(2014) Matthew W. Carson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Historical contingency and its biophysical basis in glucocorticoid receptor evolution

(2014) Michael J. Harms et al.   NATURE

The ensemble nature of allostery

(2014) Hesam N. Motlagh et al.   NATURE

Nonlinear excitations match correlated motions unveiled by NMR in proteins: a new perspective on allosteric cross-talk

(2014) Francesco Piazza   PHYSICAL BIOLOGY

Mode coupling points to functionally important residues in myosin II

(2014) Onur Varol et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A Unified View of “How Allostery Works”

(2014) Chung-Jung Tsai et al.   PLoS Computational Biology

MCPath: Monte Carlo path generation approach to predict likely allosteric pathways and functional residues

(2013) Cihan Kaya et al.   NUCLEIC ACIDS RESEARCH

Modulation of Global Low-Frequency Motions Underlies Allosteric Regulation: Demonstration in CRP/FNR Family Transcription Factors

(2013) Thomas L. Rodgers et al.   PLOS BIOLOGY

Collective Dynamics Differentiates Functional Divergence in Protein Evolution

(2012) Tyler J. Glembo et al.   PLoS Computational Biology

NMR insights into protein allostery

(2011) Gregory Manley et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Allosteric signal transmission in the nucleotide-binding domain of 70-kDa heat shock protein (Hsp70) molecular chaperones

(2011) A. Zhuravleva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allostery and population shift in drug discovery

(2010) Gozde Kar et al.   CURRENT OPINION IN PHARMACOLOGY

Principal component and normal mode analysis of proteins; a quantitative comparison using the GroEL subunit

(2010) Lars Skjaerven et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Glucocorticoid receptor (GR) β has intrinsic, GRα-independent transcriptional activity

(2009) Tomoshige Kino et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Coupling between Normal Modes Drives Protein Conformational Dynamics: Illustrations Using Allosteric Transitions in Myosin II

(2009) Wenjun Zheng et al.   BIOPHYSICAL JOURNAL

Statistical thermodynamics of residue fluctuations in native proteins

(2009) Osman N. Yogurtcu et al.   JOURNAL OF CHEMICAL PHYSICS

The mineralocorticoid receptor and its coregulators

(2009) Jun Yang et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

An epistatic ratchet constrains the direction of glucocorticoid receptor evolution

(2009) Jamie T. Bridgham et al.   NATURE

The human glucocorticoid receptor: Molecular basis of biologic function

(2009) Nicolas C. Nicolaides et al.   STEROIDS

The Origin of Allosteric Functional Modulation: Multiple Pre-existing Pathways

(2009) Antonio del Sol et al.   STRUCTURE

Allostery and cooperativity revisited

(2008) Qiang Cui et al.   PROTEIN SCIENCE