Crystal structures of MBP fusion proteins

Structure and Inhibition of Microbiome β-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity

(2015) Bret D. Wallace et al.   CHEMISTRY & BIOLOGY

Structural basis for corepressor assembly by the orphan nuclear receptor TLX

(2015) Xiaoyong Zhi et al.   GENES & DEVELOPMENT

A New Versatile Immobilization Tag Based on the Ultra High Affinity and Reversibility of the Calmodulin–Calmodulin Binding Peptide Interaction

(2015) Somnath Mukherjee et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor

(2015) Jason M. Booe et al.   MOLECULAR CELL

Positional effects of fusion partners on the yield and solubility of MBP fusion proteins

(2015) Sreejith Raran-Kurussi et al.   PROTEIN EXPRESSION AND PURIFICATION

Structural and Evolutionary Analyses Show Unique Stabilization Strategies in the Type IV Pili of Clostridium difficile

(2015) Kurt H. Piepenbrink et al.   STRUCTURE

A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1

(2015) Matthew C. Clifton et al.   PLoS One

Structure of the GH1 domain of guanylate kinase-associated protein from Rattus norvegicus

(2014) Junsen Tong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation

(2014) Jochen Baßler et al.   JOURNAL OF CELL BIOLOGY

KIF14 Binds Tightly to Microtubules and Adopts a Rigor-Like Conformation

(2014) Kritica Arora et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein

(2014) James Jung et al.   JOURNAL OF STRUCTURAL BIOLOGY

Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein

(2014) M. A. Schumacher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1)

(2014) Chao Fang et al.   ACS Medicinal Chemistry Letters

Structure and function of Norrin in assembly and activation of a Frizzled 4-Lrp5/6 complex

(2013) J. Ke et al.   GENES & DEVELOPMENT

Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly

(2013) Tengchuan Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure-function analyses of the human SIX1–EYA2 complex reveal insights into metastasis and BOR syndrome

(2013) Aaron N Patrick et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mcm10 Self-Association Is Mediated by an N-Terminal Coiled-Coil Domain

(2013) Wenyue Du et al.   PLoS One

The Crystal Structure of the Orphan Nuclear Receptor NR2E3/PNR Ligand Binding Domain Reveals a Dimeric Auto-Repressed Conformation

(2013) M. H. Eileen Tan et al.   PLoS One

Structural insights into gene repression by the orphan nuclear receptor SHP

(2013) X. Zhi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structures of an archaeal oligosaccharyltransferase provide insights into the catalytic cycle of N-linked protein glycosylation

(2013) S. Matsumoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein domain definition should allow for conditional disorder

(2013) Kavestri Yegambaram et al.   PROTEIN SCIENCE

Structure of the NLRP1 caspase recruitment domain suggests potential mechanisms for its association with procaspase-1

(2013) Tengchuan Jin et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structural Basis for Hijacking of Cellular LxxLL Motifs by Papillomavirus E6 Oncoproteins

(2013) K. Zanier et al.   SCIENCE

Crystal structure of the C-terminal globular domain of the third paralog of the Archaeoglobus fulgidus oligosaccharyltransferases

(2013) Shunsuke Matsumoto et al.   BMC STRUCTURAL BIOLOGY

Crystal structure of the Candida albicans Kar3 kinesin motor domain fused to maltose-binding protein

(2012) Caroline Delorme et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Ability to Enhance the Solubility of Its Fusion Partners Is an Intrinsic Property of Maltose-Binding Protein but Their Folding Is Either Spontaneous or Chaperone-Mediated

(2012) Sreejith Raran-Kurussi et al.   PLoS One

Structural insight into HIV-1 capsid recognition by rhesus TRIM5 

(2012) H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Survival Motor Neuron Protein Forms Soluble Glycine Zipper Oligomers

(2012) Renee Martin et al.   STRUCTURE

Structural analysis of the intracellular domain of (pro)renin receptor fused to maltose-binding protein

(2011) Yanfeng Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation

(2011) Chuanbing Bian et al.   EMBO JOURNAL

Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins

(2011) Shahir S Rizk et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors

(2011) Shiva Kumar et al.   PLoS One

Structures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation

(2011) Minglei Zhao et al.   PROTEIN SCIENCE

Crystal structure of the extracellular domain of human myelin protein zero

(2011) Zhigang Liu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Charge-Surrounded Pockets and Electrostatic Interactions with Small Ions Modulate the Activity of Retroviral Fusion Proteins

(2011) Daniel Lamb et al.   PLoS Pathogens

The structure of the dust mite allergen Der p 7 reveals similarities to innate immune proteins

(2010) Geoffrey A. Mueller et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Structural and Functional Characterization of an RNase HI Domain from the Bifunctional Protein Rv2228c from Mycobacterium tuberculosis

(2010) H. A. Watkins et al.   JOURNAL OF BACTERIOLOGY

Dimeric Arrangement of the Parathyroid Hormone Receptor and a Structural Mechanism for Ligand-induced Dissociation

(2010) Augen A. Pioszak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The 1.5 Å Crystal Structure of Human Receptor for Advanced Glycation Endproducts (RAGE) Ectodomains Reveals Unique Features Determining Ligand Binding

(2010) HaJeung Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ

(2010) James E. Brownell et al.   MOLECULAR CELL

Structural insight into the mechanisms of enveloped virus tethering by tetherin

(2010) H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Parathyroid Hormone-related Protein Binding to the Parathyroid Hormone Receptor and Design of Conformation-selective Peptides

(2009) Augen A. Pioszak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis of yeast Tim40/Mia40 as an oxidative translocator in the mitochondrial intermembrane space

(2009) S. Kawano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein-protein crystal-packing contacts

(2009) Oliviero Carugo et al.   PROTEIN SCIENCE

Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process

(2009) Jed J. W. Wiltzius et al.   PROTEIN SCIENCE

Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1

(2008) Augen A. Pioszak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein–Protein Interfaces

(2008) Ryan N. Gilbreth et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal structure of the ZP-N domain of ZP3 reveals the core fold of animal egg coats

(2008) Magnus Monné et al.   NATURE

Redirecting the substrate specificity of heparan sulfate 2-O-sulfotransferase by structurally guided mutagenesis

(2008) H. N. Bethea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular recognition of parathyroid hormone by its G protein-coupled receptor

(2008) Augen A. Pioszak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a signal transduction regulator, RACK1, fromArabidopsis thaliana

(2008) Hemayet Ullah et al.   PROTEIN SCIENCE

Crystal structure of human IPS-1/MAVS/VISA/Cardif caspase activation recruitment domain

(2008) Jane A Potter et al.   BMC STRUCTURAL BIOLOGY