Elucidation of tonic and activated B-cell receptor signaling in Burkitt’s lymphoma provides insights into regulation of cell survival

ReactomePA: an R/Bioconductor package for reactome pathway analysis and visualization

(2016) Guangchuang Yu et al.   Molecular BioSystems

PhosphoPath: Visualization of Phosphosite-centric Dynamics in Temporal Molecular Networks

(2015) Linsey M. Raaijmakers et al.   JOURNAL OF PROTEOME RESEARCH

Deep Proteomics of Mouse Skeletal Muscle Enables Quantitation of Protein Isoforms, Metabolic Pathways, and Transcription Factors

(2015) Atul S. Deshmukh et al.   MOLECULAR & CELLULAR PROTEOMICS

Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation

(2015) S. Satpathy et al.   Molecular Systems Biology

Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma

(2015) Wyndham H Wilson et al.   NATURE MEDICINE

Survival of human lymphoma cells requires B-cell receptor engagement by self-antigens

(2015) Ryan M. Young et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The biological role of actinin-4 (ACTN4) in malignant phenotypes of cancer

(2015) Kazufumi Honda   Cell and Bioscience

Improved outcome of adult Burkitt lymphoma/leukemia with rituximab and chemotherapy: report of a large prospective multicenter trial

(2014) D. Hoelzer et al.   BLOOD

Abl2/Abl-related Gene Stabilizes Actin Filaments, Stimulates Actin Branching by Actin-related Protein 2/3 Complex, and Promotes Actin Filament Severing by Cofilin

(2014) Naomi Courtemanche et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ProteomeXchange provides globally coordinated proteomics data submission and dissemination

(2014) Juan A Vizcaíno et al.   NATURE BIOTECHNOLOGY

Stage-specific control of early B cell development by the transcription factor Ikaros

(2014) Tanja A Schwickert et al.   NATURE IMMUNOLOGY

Macromolecular assembly of the adaptor SLP-65 at intracellular vesicles in resting B cells

(2014) M. Engelke et al.   Science Signaling

 2 integrin-derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis

(2013) T. Oellerich et al.   BLOOD

Base-pair resolution DNA methylome of the EBV-positive Endemic Burkitt lymphoma cell line DAUDI determined by SOLiD bisulfite-sequencing

(2013) B Kreck et al.   LEUKEMIA

Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells

(2013) Angelo Castello et al.   NATURE IMMUNOLOGY

Targeting pathological B cell receptor signalling in lymphoid malignancies

(2013) Ryan M. Young et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia

(2013) John C. Byrd et al.   NEW ENGLAND JOURNAL OF MEDICINE

An Optimized microRNA Backbone for Effective Single-Copy RNAi

(2013) Christof Fellmann et al.   Cell Reports

High-throughput SNP-based authentication of human cell lines

(2012) Felipe Castro et al.   INTERNATIONAL JOURNAL OF CANCER

Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration

(2012) J Hoellenriegel et al.   LEUKEMIA

Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling

(2012) Marcus Dühren-von Minden et al.   NATURE

Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics

(2012) Roland Schmitz et al.   NATURE

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

(2012)   NATURE GENETICS

Serine phosphorylation by SYK is critical for nuclear localization and transcription factor function of Ikaros

(2012) F. M. Uckun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Regulation of BCR signaling

(2011) Tomohiro Kurosaki   MOLECULAR IMMUNOLOGY

The Ikaros gene family: Transcriptional regulators of hematopoiesis and immunity

(2011) Liza B. John et al.   MOLECULAR IMMUNOLOGY

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

(2011) Xose S. Puente et al.   NATURE

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

(2010) R. Eric Davis et al.   NATURE

The Cytoskeleton Coordinates the Early Events of B-cell Activation

(2010) N. E. Harwood et al.   Cold Spring Harbor Perspectives in Biology

B Cell Signaling and Fate Decision

(2009) Tomohiro Kurosaki et al.   Annual Review of Immunology

SLP-65 Phosphorylation Dynamics Reveals a Functional Basis for Signal Integration by Receptor-proximal Adaptor Proteins

(2009) Thomas Oellerich et al.   MOLECULAR & CELLULAR PROTEOMICS

The Aiolos transcription factor is up-regulated in chronic lymphocytic leukemia

(2008) M. Duhamel et al.   BLOOD

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Oncogenic CARD11 Mutations in Human Diffuse Large B Cell Lymphoma

(2008) G. Lenz et al.   SCIENCE

The B Cell Antigen Receptor and Overexpression of MYC Can Cooperate in the Genesis of B Cell Lymphomas

(2008) Yosef Refaeli et al.   PLOS BIOLOGY