Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ

PDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity

(2016) Eyad Kalawy Fansa et al.   Nature Communications

A New View of Ras Isoforms in Cancers

(2015) R. Nussinov et al.   CANCER RESEARCH

K-Ras Promotes Tumorigenicity through Suppression of Non-canonical Wnt Signaling

(2015) Man-Tzu Wang et al.   CELL

The N- and C-terminal ends of RPGR can bind to PDE6 

(2015) E. K. Fansa et al.   EMBO REPORTS

K-Ras4A splice variant is widely expressed in cancer and uses a hybrid membrane-targeting motif

(2015) Frederick D. Tsai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ras moves to stay in place

(2015) Malte Schmick et al.   TRENDS IN CELL BIOLOGY

Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical studies of prenylated protein-lipid interactions

(2015) William K. Gillette et al.   Scientific Reports

Combining biophysical methods for the analysis of protein complex stoichiometry and affinity inSEDPHAT

(2015) Huaying Zhao et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Dragging Ras Back in the Ring

(2014) Andrew G. Stephen et al.   CANCER CELL

KRas Localizes to the Plasma Membrane by Spatial Cycles of Solubilization, Trapping and Vesicular Transport

(2014) Malte Schmick et al.   CELL

Membrane Protein Transport in Photoreceptors: The Function of PDE 

(2014) W. Baehr   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

(2014) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Recorded scan times can limit the accuracy of sedimentation coefficients in analytical ultracentrifugation

(2013) Huaying Zhao et al.   ANALYTICAL BIOCHEMISTRY

Mechanism of farnesylated CAAX protein processing by the intramembrane protease Rce1

(2013) Ioannis Manolaridis et al.   NATURE

Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling

(2013) Gunther Zimmermann et al.   NATURE

Regulation of Small GTPases by GEFs, GAPs, and GDIs

(2013) Jacqueline Cherfils et al.   PHYSIOLOGICAL REVIEWS

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A Comprehensive Survey of Ras Mutations in Cancer

(2012) I. A. Prior et al.   CANCER RESEARCH

Dissociation of the K-Ras4B/PDEδ Complex upon Contact with Lipid Membranes: Membrane Delivery Instead of Extraction

(2012) Katrin Weise et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

On the Distribution of Protein Refractive Index Increments

(2011) Huaying Zhao et al.   BIOPHYSICAL JOURNAL

Mechanism of Isoprenylcysteine Carboxyl Methylation from the Crystal Structure of the Integral Membrane Methyltransferase ICMT

(2011) Jing Yang et al.   MOLECULAR CELL

The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins

(2011) Anchal Chandra et al.   NATURE CELL BIOLOGY

Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

(2011) Shehab A Ismail et al.   Nature Chemical Biology

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Synthesis of the Rheb and K-Ras4B GTPases

(2010) Yong-Xiang Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Isoform-specific ras functions in development and cancer

(2009) Margaret P Quinlan et al.   Future Oncology

A model for transport of membrane-associated phototransduction polypeptides in rod and cone photoreceptor inner segments

(2007) Sukanya Karan et al.   VISION RESEARCH