Wnt/β-catenin signaling promotes self-renewal and inhibits the primed state transition in naïve human embryonic stem cells

The pluripotent state in mouse and human

(2015) K. C. Davidson et al.   DEVELOPMENT

Commercially Available Preparations of Recombinant Wnt3a Contain Non-Wnt Related Activities Which May Activate TGF-β Signaling

(2015) Jon M. Carthy et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

(2015) Henrik Sperber et al.   NATURE CELL BIOLOGY

Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells

(2015) Galbha Duggal et al.   STEM CELLS

A Simple and Robust Method for Establishing Homogeneous Mouse Epiblast Stem Cell Lines by Wnt Inhibition

(2015) Michihiko Sugimoto et al.   Stem Cell Reports

Endogenous WNT Signals Mediate BMP-Induced and Spontaneous Differentiation of Epiblast Stem Cells and Human Embryonic Stem Cells

(2015) Dorota Kurek et al.   Stem Cell Reports

Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human

(2014) Yasuhiro Takashima et al.   CELL

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

(2014) Thorold W. Theunissen et al.   Cell Stem Cell

Derivation of naive human embryonic stem cells

(2014) C. B. Ware et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Naive embryonic stem cells: the future of stem cell research?

(2014) Carol B Ware   Regenerative Medicine

Induction of a Human Pluripotent State with Distinct Regulatory Circuitry that Resembles Preimplantation Epiblast

(2013) Yun-Shen Chan et al.   Cell Stem Cell

Kinetics and Epigenetics of Retroviral Silencing in Mouse Embryonic Stem Cells Defined by Deletion of the D4Z4 Element

(2013) Sylvie Rival-Gervier et al.   MOLECULAR THERAPY

Derivation of novel human ground state naive pluripotent stem cells

(2013) Ohad Gafni et al.   NATURE

Epiblast Ground State Is Controlled by Canonical Wnt/β-Catenin Signaling in the Postimplantation Mouse Embryo and Epiblast Stem Cells

(2013) Tomoyuki Sumi et al.   PLoS One

Signaling Roadmap Modulating Naive and Primed Pluripotency

(2013) Seyedeh-Nafiseh Hassani et al.   STEM CELLS AND DEVELOPMENT

Uncovering the true identity of naïve pluripotent stem cells

(2013) Maaike Welling et al.   TRENDS IN CELL BIOLOGY

Three decades of Wnts: a personal perspective on how a scientific field developed

(2012) Roel Nusse et al.   EMBO JOURNAL

The many faces and functions of β-catenin

(2012) Tomas Valenta et al.   EMBO JOURNAL

HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition

(2012) Wenyu Zhou et al.   EMBO JOURNAL

Wnt/ -catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4

(2012) K. C. Davidson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt/ -Catenin Signaling and AXIN1 Regulate Apoptosis Triggered by Inhibition of the Mutant Kinase BRAFV600E in Human Melanoma

(2012) T. L. Biechele et al.   Science Signaling

Wnt Pathway Regulation of Embryonic Stem Cell Self-Renewal

(2012) B. J. Merrill   Cold Spring Harbor Perspectives in Biology

Impact of WNT signaling on tissue lineage differentiation in the early mouse embryo

(2011) Satomi S. Tanaka et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation

(2011) Natalia Lyashenko et al.   NATURE CELL BIOLOGY

Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells

(2011) Derk ten Berge et al.   NATURE CELL BIOLOGY

Distinct Developmental Ground States of Epiblast Stem Cell Lines Determine Different Pluripotency Features

(2011) Christof Bernemann et al.   STEM CELLS

Klf4 reverts developmentally programmed restriction of ground state pluripotency

(2009) G. Guo et al.   DEVELOPMENT

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

(2009) Baozhi Chen et al.   Nature Chemical Biology

Dynamic Equilibrium and Heterogeneity of Mouse Pluripotent Stem Cells with Distinct Functional and Epigenetic States

(2008) Katsuhiko Hayashi et al.   Cell Stem Cell

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

Silencing of the expression of pluripotent driven-reporter genes stably transfected into human pluripotent cells

(2008) Rebecca Stewart et al.   Regenerative Medicine