Growth factors and medium hyperglycemia induce Sox9+ductal cell differentiation into β cells in mice with reversal of diabetes

Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer

(2015) Joan Font-Burgada et al.   CELL

Reprogramming Mouse Cells With a Pancreatic Duct Phenotype to Insulin-Producing β-Like Cells

(2015) Takatsugu Yamada et al.   ENDOCRINOLOGY

Long-term persistence and development of induced pancreatic beta cells generated by lineage conversion of acinar cells

(2014) Weida Li et al.   NATURE BIOTECHNOLOGY

Combination therapy with sitagliptin and lansoprazole in patients with recent-onset type 1 diabetes (REPAIR-T1D): 12-month results of a multicentre, randomised, placebo-controlled, phase 2 trial

(2014) Kurt J Griffin et al.   Lancet Diabetes & Endocrinology

Islet β cell mass in diabetes and how it relates to function, birth, and death

(2013) Gordon C. Weir et al.   Annals of the New York Academy of Sciences

Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration

(2013) F. C. Pan et al.   DEVELOPMENT

Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel

(2013) L. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vitro Multilineage Differentiation and Self-Renewal of Single Pancreatic Colony-Forming Cells from Adult C57Bl/6 Mice

(2013) Liang Jin et al.   STEM CELLS AND DEVELOPMENT

β-cell dedifferentiation in diabetes is important, but what is it?

(2013) Gordon C Weir et al.   Islets

Mixed Chimerism and Growth Factors Augment   Cell Regeneration and Reverse Late-Stage Type 1 Diabetes

(2012) M. Wang et al.   Science Translational Medicine

Concise Review: Pancreas Regeneration: Recent Advances and Perspectives

(2012) Philippe A. Lysy et al.   Stem Cells Translational Medicine

Progenitor cell domains in the developing and adult pancreas

(2011) Janel L. Kopp et al.   CELL CYCLE

The Adult Mouse and Human Pancreas Contain Rare Multipotent Stem Cells that Express Insulin

(2011) Simon R. Smukler et al.   Cell Stem Cell

Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas

(2011) J. L. Kopp et al.   DEVELOPMENT

Duct Cells Contribute to Regeneration of Endocrine and Acinar Cells Following Pancreatic Damage in Adult Mice

(2011) Angela Criscimanna et al.   GASTROENTEROLOGY

Exocrine-to-endocrine differentiation is detectable only prior to birth in the uninjured mouse pancreas

(2010) Daniel Kopinke et al.   BMC DEVELOPMENTAL BIOLOGY

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine

(2010) Kenichiro Furuyama et al.   NATURE GENETICS

Pancreatic β-Cell Neogenesis by Direct Conversion from Mature α-Cells

(2010) Cheng-Ho Chung et al.   STEM CELLS

An Acidic pH and Activation of Phosphoinositide 3-Kinase Stimulate Differentiation of Pancreatic Progenitors Into Insulin-Producing Cells

(2010) T. Koblas et al.   TRANSPLANTATION PROCEEDINGS

Pancreatic Exocrine Duct Cells Give Rise to Insulin-Producing β Cells during Embryogenesis but Not after Birth

(2009) Myriam Solar et al.   DEVELOPMENTAL CELL

The Clinical Impact of Islet Transplantation

(2008) P. Fiorina et al.   AMERICAN JOURNAL OF TRANSPLANTATION

β Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas

(2008) Xiaobo Xu et al.   CELL

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE

Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth

(2008) A. Inada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA