Concise Review: Pancreas Regeneration: Recent Advances and Perspectives

Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells

(2011) K. Hu et al.   BLOOD

Targeting SOX17 in Human Embryonic Stem Cells Creates Unique Strategies for Isolating and Analyzing Developing Endoderm

(2011) Pei Wang et al.   Cell Stem Cell

Epigenetic Memory and Preferential Lineage-Specific Differentiation in Induced Pluripotent Stem Cells Derived from Human Pancreatic Islet Beta Cells

(2011) Ori Bar-Nur et al.   Cell Stem Cell

Dynamic Changes in the Copy Number of Pluripotency and Cell Proliferation Genes in Human ESCs and iPSCs during Reprogramming and Time in Culture

(2011) Louise C. Laurent et al.   Cell Stem Cell

The Adult Mouse and Human Pancreas Contain Rare Multipotent Stem Cells that Express Insulin

(2011) Simon R. Smukler et al.   Cell Stem Cell

Direct Lineage Conversion of Terminally Differentiated Hepatocytes to Functional Neurons

(2011) Samuele Marro et al.   Cell Stem Cell

Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency

(2011) Frederick Anokye-Danso et al.   Cell Stem Cell

Suppression of Ptf1a Activity Induces Acinar-to-Endocrine Conversion

(2011) Daniel Hesselson et al.   CURRENT BIOLOGY

State of the Art of Clinical Islet Transplantation and Novel Protocols of Immunosuppression

(2011) A. M. James Shapiro   Current Diabetes Reports

Immunoisolation of Pancreatic Islet Grafts with No Recipient’s Immunosuppression: Actual and Future Perspectives

(2011) Giuseppe Basta et al.   Current Diabetes Reports

Pig-to-Nonhuman Primates Pancreatic Islet Xenotransplantation: An Overview

(2011) Marco Marigliano et al.   Current Diabetes Reports

Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas

(2011) J. L. Kopp et al.   DEVELOPMENT

Ongoing β-Cell Turnover in Adult Nonhuman Primates Is Not Adaptively Increased in Streptozotocin-Induced Diabetes

(2011) Yoshifumi Saisho et al.   DIABETES

How Does Type 1 Diabetes Develop?: The Notion of Homicide or  -Cell Suicide Revisited

(2011) M. A. Atkinson et al.   DIABETES

Incretin Effects on  -Cell Function, Replication, and Mass: The human perspective

(2011) A. J. Garber   DIABETES CARE

Long-Acting Glucagon-Like Peptide 1 Receptor Agonists: A review of their efficacy and tolerability

(2011) A. J. Garber   DIABETES CARE

Generation of pancreatic insulin-producing cells from rhesus monkey induced pluripotent stem cells

(2011) F. F. Zhu et al.   DIABETOLOGIA

The role of pluripotent embryonic-like stem cells residing in adult tissues in regeneration and longevity

(2011) Mariusz Z. Ratajczak et al.   DIFFERENTIATION

Islets Transplanted in Immunoisolation Devices: A Review of the Progress and the Challenges that Remain

(2011) Esther S. O'Sullivan et al.   ENDOCRINE REVIEWS

Duct Cells Contribute to Regeneration of Endocrine and Acinar Cells Following Pancreatic Damage in Adult Mice

(2011) Angela Criscimanna et al.   GASTROENTEROLOGY

Teplizumab for treatment of type 1 diabetes (Protégé study): 1-year results from a randomised, placebo-controlled trial

(2011) Nicole Sherry et al.   LANCET

Insulin-producing Surrogate β-cells From Embryonic Stem Cells: Are We There Yet?

(2011) Ortwin Naujok et al.   MOLECULAR THERAPY

Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1

(2011) Momoko Maekawa et al.   NATURE

Somatic coding mutations in human induced pluripotent stem cells

(2011) Athurva Gore et al.   NATURE

Immunomodulatory therapy to preserve pancreatic β-cell function in type 1 diabetes

(2011) Frank Waldron-Lynch et al.   NATURE REVIEWS DRUG DISCOVERY

In vivo tracking of 111In-oxine labeled mesenchymal stem cells following infusion in patients with advanced cirrhosis

(2011) Ali Gholamrezanezhad et al.   NUCLEAR MEDICINE AND BIOLOGY

The Antidiabetic Effect of MSCs Is Not Impaired by Insulin Prophylaxis and Is Not Improved by a Second Dose of Cells

(2011) Fernando Ezquer et al.   PLoS One

Differentiation of human embryonic stem cells into pancreatic endoderm in patterned size-controlled clusters

(2011) Dennis Van Hoof et al.   Stem Cell Research

CD24: A Novel Surface Marker for PDX1-Positive Pancreatic Progenitors Derived from Human Embryonic Stem Cells

(2011) Wei Jiang et al.   STEM CELLS

Concise Review: Mesenchymal Stem Cells for Acute Lung Injury: Role of Paracrine Soluble Factors

(2011) Jae W. Lee et al.   STEM CELLS

Microcapsules and microcarriers for in situ cell delivery☆

(2010) Rosa Ma Hernández et al.   ADVANCED DRUG DELIVERY REVIEWS

Reprogramming of Human Primary Somatic Cells by OCT4 and Chemical Compounds

(2010) Saiyong Zhu et al.   Cell Stem Cell

Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA

(2010) Luigi Warren et al.   Cell Stem Cell

Induced Pluripotent Stem (iPS) Cell Research Overview

(2010) Shih-Ping Liu et al.   CELL TRANSPLANTATION

Recent Advances and Prospects in the Differentiation of Pancreatic Cells From Human Embryonic Stem Cells

(2010) J. K. Mfopou et al.   DIABETES

Congenic Mesenchymal Stem Cell Therapy Reverses Hyperglycemia in Experimental Type 1 Diabetes

(2010) M. Jurewicz et al.   DIABETES

 -Cell Replication Is Increased in Donor Organs From Young Patients After Prolonged Life Support

(2010) P. I. Veld et al.   DIABETES

 -Cell Growth and Regeneration: Replication Is Only Part of the Story

(2010) S. Bonner-Weir et al.   DIABETES

Production of Functional Glucagon-Secreting  -Cells From Human Embryonic Stem Cells

(2010) A. Rezania et al.   DIABETES

Residual Insulin Production and Pancreatic  -Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study

(2010) H. A. Keenan et al.   DIABETES

Evidence of increased islet cell proliferation in patients with recent-onset type 1 diabetes

(2010) A. Willcox et al.   DIABETOLOGIA

Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy

(2010) A. E. Butler et al.   DIABETOLOGIA

Mesenchymal stem cells: Paracrine signaling and differentiation during cutaneous wound repair

(2010) Anne M. Hocking et al.   EXPERIMENTAL CELL RESEARCH

Synthesized basement membranes direct the differentiation of mouse embryonic stem cells into pancreatic lineages

(2010) Y. Higuchi et al.   JOURNAL OF CELL SCIENCE

Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult rats

(2010) W.-C. Li et al.   JOURNAL OF CELL SCIENCE

Significant Human β-Cell Turnover Is Limited to the First Three Decades of Life as Determined byin VivoThymidine Analog Incorporation and Radiocarbon Dating

(2010) S. Perl et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Current Status of Islet Cell Replacement and Regeneration Therapy

(2010) Philippe A. Halban et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Network Analysis of Primary Hepatocyte Dedifferentiation Using a Shotgun Proteomics Approach

(2010) Cliff Rowe et al.   JOURNAL OF PROTEOME RESEARCH

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

(2010) Jose M Polo et al.   NATURE BIOTECHNOLOGY

Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine

(2010) Kenichiro Furuyama et al.   NATURE GENETICS

Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic  -like cells

(2010) Z. Alipio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small-molecule inducers of insulin expression in pancreatic  -cells

(2010) D. Fomina-Yadlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beta cell regeneration in human pancreas

(2010) Roberto Gianani   Seminars in Immunopathology

Elimination of tumorigenic stem cells from differentiated progeny and selection of definitive endoderm reveals a Pdx1+ foregut endoderm stem cell lineage

(2010) Brenda Kahan et al.   Stem Cell Research

Alginate Macroencapsulation of Pig Islets Allows Correction of Streptozotocin-Induced Diabetes in Primates up to 6 Months Without Immunosuppression

(2010) Denis Dufrane et al.   TRANSPLANTATION

Islet Transplantation in Type 1 Diabetic Patients Using Calcineurin Inhibitor-Free Immunosuppressive Protocols Based on T-Cell Adhesion or Costimulation Blockade

(2010) Andrew M. Posselt et al.   TRANSPLANTATION

β-Cell regeneration: the pancreatic intrinsic faculty

(2010) Renaud Desgraz et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Endoscopic Gastric Submucosal Transplantation of Islets (ENDO-STI): Technique and Initial Results in Diabetic Pigs

(2009) G. J. Echeverri et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The reversal of hyperglycaemia in diabetic mice using PLGA scaffolds seeded with islet-like cells derived from human embryonic stem cells

(2009) Gen-hong Mao et al.   BIOMATERIALS

The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells

(2009) Patrick Collombat et al.   CELL

Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells

(2009) Donghui Zhang et al.   CELL RESEARCH

Molecules that Promote or Enhance Reprogramming of Somatic Cells to Induced Pluripotent Stem Cells

(2009) Bo Feng et al.   Cell Stem Cell

Small Molecules Efficiently Direct Endodermal Differentiation of Mouse and Human Embryonic Stem Cells

(2009) Malgorzata Borowiak et al.   Cell Stem Cell

Safety and Viability of Microencapsulated Human Islets Transplanted Into Diabetic Humans

(2009) B. E. Tuch et al.   DIABETES CARE

Effects of therapy in type 1 and type 2 diabetes mellitus with a peptide derived from islet neogenesis associated protein (INGAP)

(2009) Kathleen M. Dungan et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Mesenchymal stem cells protect NOD mice from diabetes by inducing regulatory T cells

(2009) A. M. Madec et al.   DIABETOLOGIA

C-Peptide Levels and Insulin Independence Following Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus

(2009) Carlos E. B. Couri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Fibroblast Growth Factor-1 (FGF-1) Loaded Microbeads Enhance Local Capillary Neovascularization

(2009) Monica L. Moya et al.   JOURNAL OF SURGICAL RESEARCH

A small molecule that directs differentiation of human ESCs into the pancreatic lineage

(2009) Shuibing Chen et al.   Nature Chemical Biology

Mesenchymal Stem Cells Derived From Human Exocrine Pancreas Express Transcription Factors Implicated in Beta-Cell Development

(2009) Reto M. Baertschiger et al.   PANCREAS

Epithelial-Mesenchymal Transition in Cells Expanded In Vitro from Lineage-Traced Adult Human Pancreatic Beta Cells

(2009) Holger A. Russ et al.   PLoS One

Generation of pluripotent stem cells from patients with type 1 diabetes

(2009) R. Maehr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human β-cell Precursors Mature Into Functional Insulin-producing Cells in an Immunoisolation Device: Implications for Diabetes Cell Therapies

(2009) Seung-Hee Lee et al.   TRANSPLANTATION

β Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas

(2008) Xiaobo Xu et al.   CELL

Biohybrid Devices and Encapsulation Technologies for Engineering a Bioartificial Pancreas

(2008) Alexander Fort et al.   CELL TRANSPLANTATION

Intra-Endodermal Interactions Are Required for Pancreatic β Cell Induction

(2008) Won-Suk Chung et al.   DEVELOPMENTAL CELL

Immunomodulation by Mesenchymal Stem Cells: A Potential Therapeutic Strategy for Type 1 Diabetes

(2008) R. Abdi et al.   DIABETES

Combination Therapy With Glucagon-Like Peptide-1 and Gastrin Restores Normoglycemia in Diabetic NOD Mice

(2008) W. L. Suarez-Pinzon et al.   DIABETES

 -Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of  -Cell Mass in Humans

(2008) J. J. Meier et al.   DIABETES

In Vitro Proliferation of Cells Derived From Adult Human  -Cells Revealed By Cell-Lineage Tracing

(2008) H. A. Russ et al.   DIABETES

Insulin protein and proliferation in ductal cells in the transplanted pancreas of patients with type 1 diabetes and recurrence of autoimmunity

(2008) A. Martin-Pagola et al.   DIABETOLOGIA

Impaired islet turnover in human donor pancreata with aging

(2008) Christina Reers et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Generation of Insulin-secreting Islet-like Clusters from Human Skin Fibroblasts

(2008) Keisuke Tateishi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

(2008) Evert Kroon et al.   NATURE BIOTECHNOLOGY

Islet-Like Clusters Derived from Mesenchymal Stem Cells in Wharton's Jelly of the Human Umbilical Cord for Transplantation to Control Type 1 Diabetes

(2008) Kuo Ching Chao et al.   PLoS One