Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling
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Title
Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 113, Issue 51, Pages 14751-14756
Publisher
Proceedings of the National Academy of Sciences
Online
2016-12-06
DOI
10.1073/pnas.1612520114
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Note: Only part of the references are listed.- Multiple Weak Linear Motifs Enhance Recruitment and Processivity in SPOP-Mediated Substrate Ubiquitination
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- The skeleton: a multi-functional complex organ. The growth plate chondrocyte and endochondral ossification
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- Osteoporosis: now and the future
- (2011) Tilman D Rachner et al. LANCET
- Building strong bones: molecular regulation of the osteoblast lineage
- (2011) Fanxin Long NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors
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- (2010) Kathryn C. Claiborn et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2010) X. Wen et al. MOLECULAR AND CELLULAR BIOLOGY
- The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization
- (2009) K. S. Joeng et al. DEVELOPMENT
- Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
- (2009) M.-H. Chen et al. GENES & DEVELOPMENT
- Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases
- (2009) Min Zhuang et al. MOLECULAR CELL
- Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase
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