Diabetic wound regeneration using peptide-modified hydrogels to target re-epithelialization

Engineered human vascularized constructs accelerate diabetic wound healing

(2016) Yu-I Shen et al.   BIOMATERIALS

Tailoring chitosan/collagen scaffolds for tissue engineering: Effect of composition and different crosslinking agents on scaffold properties

(2015) A. Martínez et al.   CARBOHYDRATE POLYMERS

Hydrogels With Integrin-Binding Angiopoietin-1-Derived Peptide, QHREDGS, for Treatment of Acute Myocardial Infarction

(2015) L. A. Reis et al.   Circulation-Heart Failure

Proinsulin C-Peptide Prevents Impaired Wound Healing by Activating Angiogenesis in Diabetes

(2015) Young-Cheol Lim et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Acellular Hydrogels for Regenerative Burn Wound Healing: Translation from a Porcine Model

(2015) Yu-I Shen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Modifications of collagen-based biomaterials with immobilized growth factors or peptides

(2015) Yun Xiao et al.   METHODS

siRNA-based spherical nucleic acids reverse impaired wound healing in diabetic mice by ganglioside GM3 synthase knockdown

(2015) Pratik S. Randeria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of apoptosis in human induced pluripotent stem cells during expansion in a defined culture using angiopoietin-1 derived peptide QHREDGS

(2014) Lan T.H. Dang et al.   BIOMATERIALS

Nonautonomous contact guidance signaling during collective cell migration

(2014) Camila Londono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing

(2014) M. M. Martino et al.   SCIENCE

Wound repair and regeneration: Mechanisms, signaling, and translation

(2014) S. A. Eming et al.   Science Translational Medicine

Angiopoietin-1 peptide QHREDGS promotes osteoblast differentiation, bone matrix deposition and mineralization on biomedical materials

(2014) Nicole T. Feric et al.   Biomaterials Science

Phase I trial on the safety of topical rhVEGF on chronic neuropathic diabetic foot ulcers

(2014) J.R. Hanft et al.   Journal of Wound Care

Epithelialization in Wound Healing: A Comprehensive Review

(2014) Irena Pastar et al.   Advances in Wound Care

Dual growth factor releasing multi-functional nanofibers for wound healing

(2013) Zhiwei Xie et al.   Acta Biomaterialia

Topical secretoneurin gene therapy accelerates diabetic wound healing by interaction between heparan-sulfate proteoglycans and basic FGF

(2013) Karin Albrecht-Schgoer et al.   ANGIOGENESIS

High-Glucose Environment Enhanced Oxidative Stress and Increased Interleukin-8 Secretion From Keratinocytes: New Insights Into Impaired Diabetic Wound Healing

(2013) C.-C. E. Lan et al.   DIABETES

Wounded cells drive rapid epidermal repair in the early Drosophila embryo

(2013) Rodrigo Fernandez-Gonzalez et al.   MOLECULAR BIOLOGY OF THE CELL

Propulsion and navigation within the advancing monolayer sheet

(2013) Jae Hun Kim et al.   NATURE MATERIALS

Epithelial bridges maintain tissue integrity during collective cell migration

(2013) Sri Ram Krishna Vedula et al.   NATURE MATERIALS

Loss of Innervation and Axon Plasticity Accompanies Impaired Diabetic Wound Healing

(2013) Chu Cheng et al.   PLoS One

QHREDGS Enhances Tube Formation, Metabolism and Survival of Endothelial Cells in Collagen-Chitosan Hydrogels

(2013) Jason W. Miklas et al.   PLoS One

Fibronectin Matrix Mimetics Promote Full-Thickness Wound Repair in Diabetic Mice

(2013) Daniel C. Roy et al.   TISSUE ENGINEERING PART A

Integration and Regression of Implanted Engineered Human Vascular Networks During Deep Wound Healing

(2013) Donny Hanjaya-Putra et al.   Stem Cells Translational Medicine

Reduced Innervation and Delayed Re-Innervation After Epithelial Wounding in Type 2 Diabetic Goto-Kakizaki Rats

(2012) Feng Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

The Role of MicroRNA-146a in the Pathogenesis of the Diabetic Wound-Healing Impairment: Correction With Mesenchymal Stem Cell Treatment

(2012) J. Xu et al.   DIABETES

Concise Review: Adipose-Derived Stem Cells as a Novel Tool for Future Regenerative Medicine

(2012) Hiroshi Mizuno et al.   STEM CELLS

Food and Drug Administration (FDA) drug approval end points for chronic cutaneous ulcer studies

(2012) William H. Eaglstein et al.   WOUND REPAIR AND REGENERATION

Concise Review: Clinical Translation of Wound Healing Therapies Based on Mesenchymal Stem Cells

(2012) Wesley M. Jackson et al.   Stem Cells Translational Medicine

A peptide-modified chitosan–collagen hydrogel for cardiac cell culture and delivery

(2011) Lewis A. Reis et al.   Acta Biomaterialia

Pericyte Requirement for Anti-Leak Action of Angiopoietin-1 and Vascular Remodeling in Sustained Inflammation

(2011) Jonas Fuxe et al.   AMERICAN JOURNAL OF PATHOLOGY

Controlled release of thymosin β4 using collagen–chitosan composite hydrogels promotes epicardial cell migration and angiogenesis

(2011) Loraine L.Y. Chiu et al.   JOURNAL OF CONTROLLED RELEASE

Dextran hydrogel scaffolds enhance angiogenic responses and promote complete skin regeneration during burn wound healing

(2011) G. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chitosan—A versatile semi-synthetic polymer in biomedical applications

(2011) M. Dash et al.   PROGRESS IN POLYMER SCIENCE

Engineering the Growth Factor Microenvironment with Fibronectin Domains to Promote Wound and Bone Tissue Healing

(2011) M. M. Martino et al.   Science Translational Medicine

Tissue-engineered provisional matrix as a novel approach to enhance diabetic wound healing

(2011) Swathi Balaji et al.   WOUND REPAIR AND REGENERATION

Photocrosslinkable chitosan modified with angiopoietin-1 peptide, QHREDGS, promotes survival of neonatal rat heart cells

(2010) Fiona Rask et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Biomimeticity in tissue engineering scaffolds through synthetic peptide modifications-Altering chemistry for enhanced biological response

(2010) Kumaran G. Sreejalekshmi et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Angiopoietin-1 Reduces H2O2-Induced Increases in Reactive Oxygen Species and Oxidative Damage to Skin Cells

(2010) Nesreen S. Ismail et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Hydrogels modified with QHREDGS peptide support cardiomyocyte survival in vitro and after sub-cutaneous implantation

(2010) Fiona Rask et al.   Soft Matter

Hyperglycaemic conditions hamper keratinocyte locomotion via sequential inhibition of distinct pathways: new insights on poor wound closure in patients with diabetes

(2009) C-C.E. Lan et al.   BRITISH JOURNAL OF DERMATOLOGY

Complexity in biomaterials for tissue engineering

(2009) Elsie S. Place et al.   NATURE MATERIALS

Human skin wounds: A major and snowballing threat to public health and the economy

(2009) Chandan K. Sen et al.   WOUND REPAIR AND REGENERATION

Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression

(2008) Alessandra Bitto et al.   CLINICAL SCIENCE

Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy

(2008) Susan M. Dallabrida et al.   FASEB JOURNAL

Chitosan derivatives obtained by chemical modifications for biomedical and environmental applications

(2008) N.M. Alves et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Deregulation of keratinocyte differentiation and activation: a hallmark of venous ulcers

(2008) Olivera Stojadinovic et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Oxidative stress in normal and impaired wound repair

(2008) M SCHAFER et al.   PHARMACOLOGICAL RESEARCH

Acceleration of Diabetic Wound Healing by an Angiopoietin Peptide Mimetic

(2008) Paul Van Slyke et al.   TISSUE ENGINEERING PART A