Single cell lineage tracing reveals a role for TgfβR2 in intestinal stem cell dynamics and differentiation
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Title
Single cell lineage tracing reveals a role for TgfβR2 in intestinal stem cell dynamics and differentiation
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 113, Issue 43, Pages 12192-12197
Publisher
Proceedings of the National Academy of Sciences
Online
2016-10-12
DOI
10.1073/pnas.1611980113
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- (2011) Trevor M. Yeung et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Different phenotypic consequences of simultaneous versus stepwise Apc loss
- (2011) J M Fischer et al. ONCOGENE
- Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells
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- (2008) Ashleigh J Miller et al. NATURE METHODS
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