P-TEFb Kinase Activity Is Essential for Global Transcription, Resumption of Meiosis and Embryonic Genome Activation in Pig

Nucleolus-like bodies of fully-grown mouse oocytes contain key nucleolar proteins but are impoverished for rRNA

(2015) Kseniya V. Shishova et al.   DEVELOPMENTAL BIOLOGY

Characterization of Human Cyclin-Dependent Kinase 12 (CDK12) and CDK13 Complexes in C-Terminal Domain Phosphorylation, Gene Transcription, and RNA Processing

(2015) Kaiwei Liang et al.   MOLECULAR AND CELLULAR BIOLOGY

P-TEFb, the Super Elongation Complex and Mediator Regulate a Subset of Non-paused Genes during Early Drosophila Embryo Development

(2015) Olle Dahlberg et al.   PLoS Genetics

Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73

(2015) Frankie Lam et al.   Oncotarget

Ctk1 Function Is Necessary for Full Translation Initiation Activity in Saccharomyces cerevisiae

(2014) Britta Coordes et al.   EUKARYOTIC CELL

Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons

(2014) Iris Jonkers et al.   eLife

Upstream binding factor-dependent and pre-rRNA transcription-independent association of pre-rRNA processing factors with rRNA gene

(2013) Shuhei Ueshima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cyclin-dependent Kinase 9 Links RNA Polymerase II Transcription to Processing of Ribosomal RNA

(2013) Kaspar Burger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Halogenated nucleotide labeling of nascent RNAs reveals dynamic transcription in growing pig oocytes

(2012) Reza K. Oqani et al.   DEVELOPMENTAL DYNAMICS

Cdk1, but not Cdk2, is the sole Cdk that is essential and sufficient to drive resumption of meiosis in mouse oocytes

(2012) D. Adhikari et al.   HUMAN MOLECULAR GENETICS

RNA polymerase II transcriptional silencing in growing and fully grown germinal vesicle oocytes isolated from gonadotropin-stimulated and non-stimulated gilts

(2012) Irena Barnetova et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Cyclin-Dependent Kinase 9 Activity Regulates Neutrophil Spontaneous Apoptosis

(2012) Keqing Wang et al.   PLoS One

Maternally recruited Aurora C kinase is more stable than Aurora B to support mouse oocyte maturation and early development

(2012) K. Schindler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The CDK9/Cyclin T1 subunits of P-TEFb in mouse oocytes and preimplantation embryos: A possible role in embryonic genome activation

(2011) Reza K Oqani et al.   BMC DEVELOPMENTAL BIOLOGY

What does it take to make a developmentally competent mammalian egg?

(2011) M. Zuccotti et al.   HUMAN REPRODUCTION UPDATE

Flavopiridol Protects Against Inflammation by Attenuating Leukocyte-Endothelial Interaction via Inhibition of Cyclin-Dependent Kinase 9

(2010) Ulrike K. Schmerwitz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Chemotherapeutic Drugs Inhibit Ribosome Biogenesis at Various Levels

(2010) Kaspar Burger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global Gene Silencing is Caused by the Dissociation of RNA Polymerase II from DNA in Mouse Oocytes

(2010) Ken-ichiro ABE et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

CDK9 Regulates AR Promoter Selectivity and Cell Growth through Serine 81 Phosphorylation

(2010) Vicki Gordon et al.   MOLECULAR ENDOCRINOLOGY

Prophase I arrest and progression to metaphase I in mouse oocytes: comparison of resumption of meiosis and recovery from G2-arrest in somatic cells

(2010) P. Solc et al.   MOLECULAR HUMAN REPRODUCTION

Nuclear Speckles

(2010) D. L. Spector et al.   Cold Spring Harbor Perspectives in Biology

The nucleolus: structure/function relationship in RNA metabolism

(2010) Danièle Hernandez-Verdun et al.   Wiley Interdisciplinary Reviews-RNA

SNS-032 is a potent and selective CDK 2, 7 and 9 inhibitor that drives target modulation in patient samples

(2009) Andrew Conroy et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

P-TEFb- the final frontier

(2009) Jiri Kohoutek   Cell Division

The Epigenetics of rRNA Genes: From Molecular to Chromosome Biology

(2008) Brian McStay et al.   Annual Review of Cell and Developmental Biology

The multi-tasking P-TEFb complex

(2008) Vanessa Brès et al.   CURRENT OPINION IN CELL BIOLOGY

Chromatin configurations in the germinal vesicle of mammalian oocytes

(2008) J.-H. Tan et al.   MOLECULAR HUMAN REPRODUCTION