Human PIEZO1 Ion Channel Functions as a Split Protein

Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension

(2016) Charles D. Cox et al.   Nature Communications

Piezo1 ion channel pore properties are dictated by C-terminal region

(2015) Bertrand Coste et al.   Nature Communications

Mechanical sensitivity of Piezo1 ion channels can be tuned by cellular membrane tension

(2015) Amanda H Lewis et al.   eLife

Ionic Selectivity and Permeation Properties of Human PIEZO1 Channels

(2015) Radhakrishnan Gnanasambandam et al.   PLoS One

Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors

(2014) Srdjan Maksimovic et al.   NATURE

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Piezo2 channel conductance and localization domains in Merkel cells of rat whisker hair follicles

(2014) Ryo Ikeda et al.   NEUROSCIENCE LETTERS

Stochastic nanoroughness modulates neuron–astrocyte interactions and function via mechanosensing cation channels

(2014) Nils R. Blumenthal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells

(2014) Medha M. Pathak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage

(2014) Whasil Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human PIEZO1: Removing Inactivation

(2013) Chilman Bae et al.   BIOPHYSICAL JOURNAL

Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1

(2013) I. Andolfo et al.   BLOOD

Piezo1 plays a role in erythrocyte volume homeostasis

(2013) A. Faucherre et al.   HAEMATOLOGICA

Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1

(2013) C. Bae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in the mechanotransduction protein PIEZO1 are associated with hereditary xerocytosis

(2012) R. Zarychanski et al.   BLOOD

Gating the mechanical channel Piezo1

(2012) Philip A. Gottlieb et al.   Channels

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

The role of Drosophila Piezo in mechanical nociception

(2012) Sung Eun Kim et al.   NATURE

The Mechanosensitive Ion Channel Piezo1 Is Inhibited by the Peptide GsMTx4

(2011) Chilman Bae et al.   BIOCHEMISTRY

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Integrin activation by Fam38A uses a novel mechanism of R-Ras targeting to the endoplasmic reticulum

(2009) B. J. McHugh et al.   JOURNAL OF CELL SCIENCE