Interaction of Toll-Like Receptors with the Molecular Chaperone Gp96 Is Essential for Its Activation of Cytotoxic T Lymphocyte Response

Cell membrane gp96 facilitates HER2 dimerization and serves as a novel target in breast cancer

(2015) Xin Li et al.   INTERNATIONAL JOURNAL OF CANCER

Phylogenetic Conservation of Glycoprotein 96 Ability to Interact with CD91 and Facilitate Antigen Cross-Presentation

(2014) J. Robert et al.   JOURNAL OF IMMUNOLOGY

α7 Helix Region of αI Domain Is Crucial for Integrin Binding to Endoplasmic Reticulum Chaperone gp96

(2013) Feng Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: Novel Vaccination Modality Provides Significant Protection against Mucosal Infection by Highly Pathogenic Simian Immunodeficiency Virus

(2013) N. Strbo et al.   JOURNAL OF IMMUNOLOGY

Identification of the Cellular Sentinels for Native Immunogenic Heat Shock Proteins In Vivo

(2013) M. N. Messmer et al.   JOURNAL OF IMMUNOLOGY

Induction of Regulatory T Cells by High-Dose gp96 Suppresses Murine Liver Immune Hyperactivation

(2013) Xinghui Li et al.   PLoS One

Formation of peste des petits ruminants spikeless virus-like particles by co-expression of M and N proteins in insect cells

(2013) Fuxiao Liu et al.   RESEARCH IN VETERINARY SCIENCE

Placenta-derived gp96 as a multivalent prophylactic cancer vaccine

(2013) Bao Zhao et al.   Scientific Reports

Individual Patient-Specific Immunity against High-Grade Glioma after Vaccination with Autologous Tumor Derived Peptides Bound to the 96 KD Chaperone Protein

(2012) C. A. Crane et al.   CLINICAL CANCER RESEARCH

The Molecular Chaperone gp96/GRP94 Interacts with Toll-like Receptors and Integrins via Its C-terminal Hydrophobic Domain

(2012) Shuang Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TAT-mediated gp96 transduction to APCs enhances gp96-induced antiviral and antitumor T cell responses

(2012) Bao Zhao et al.   VACCINE

Active-specific immunotherapy of human cancers with the heat shock protein Gp96-revisited

(2011) Marco Randazzo et al.   INTERNATIONAL JOURNAL OF CANCER

Heat shock protein gp96 enhances humoral and T cell responses, decreases Treg frequency and potentiates the anti-HBV activity in BALB/c and transgenic mice

(2011) Saifeng Wang et al.   VACCINE

CD91-dependent programming of T-helper cell responses following heat shock protein immunization

(2011) Sudesh Pawaria et al.   Nature Communications

Hansenula polymorpha expressed heat shock protein gp96 exerts potent T cell activation activity as an adjuvant

(2010) Yang Li et al.   JOURNAL OF BIOTECHNOLOGY

Ovalbumin-Derived Precursor Peptides Are Transferred Sequentially from gp96 and Calreticulin to MHC Class I in the Endoplasmic Reticulum

(2010) L. E. Kropp et al.   JOURNAL OF IMMUNOLOGY

Re-Examination of CD91 Function in GRP94 (Glycoprotein 96) Surface Binding, Uptake, and Peptide Cross-Presentation

(2010) A. R. Jockheck-Clark et al.   JOURNAL OF IMMUNOLOGY

Treg suppress CTL responses upon immunization with HSP gp96

(2009) Zhen Liu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Vitespen: a preclinical and clinical review

(2009) Christopher G Wood et al.   Future Oncology

Efficient Cross-Priming of Antiviral CD8+ T Cells by Antigen Donor Cells Is GRP94 Independent

(2009) A. Lev et al.   JOURNAL OF IMMUNOLOGY

Redundancy renders the glycoprotein 96 receptor scavenger receptor A dispensable for cross primingin vivo

(2008) Eric F. Tewalt et al.   IMMUNOLOGY