Interleukin 6 Accelerates Mortality by Promoting the Progression of the Systemic Lupus Erythematosus-Like Disease of BXSB.Yaa Mice

Evidence for Genes in Addition to Tlr7 in the Yaa Translocation Linked with Acceleration of Systemic Lupus Erythematosus

(2014) M.-L. Santiago-Raber et al.   JOURNAL OF IMMUNOLOGY

Genetic susceptibility to SLE: Recent progress from GWAS

(2013) Yong Cui et al.   JOURNAL OF AUTOIMMUNITY

IL-21 Is a Double-Edged Sword in the Systemic Lupus Erythematosus-like Disease of BXSB.Yaa Mice

(2013) C. G. McPhee et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: STAT1 Is Required for IL-6-Mediated Bcl6 Induction for Early Follicular Helper Cell Differentiation

(2013) Y. S. Choi et al.   JOURNAL OF IMMUNOLOGY

A meta-analysis of the association of IL-6 −174 G/C and −572 G/C polymorphisms with systemic lupus erythematosus risk

(2013) Zaixing Yang et al.   RHEUMATOLOGY INTERNATIONAL

IL-6 Triggers IL-21 production by human CD4+ T cells to drive STAT3-dependent plasma cell differentiation in B cells

(2012) Sean A Diehl et al.   IMMUNOLOGY AND CELL BIOLOGY

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

MHC Class I Family Proteins Retard Systemic Lupus Erythematosus Autoimmunity and B Cell Lymphomagenesis

(2011) C. G. McPhee et al.   JOURNAL OF IMMUNOLOGY

IL-21 and IL-6 Are Critical for Different Aspects of B Cell Immunity and Redundantly Induce Optimal Follicular Helper CD4 T Cell (Tfh) Differentiation

(2011) Danelle Eto et al.   PLoS One

The type I interferon system in the development of lupus

(2011) Lars Rönnblom et al.   SEMINARS IN IMMUNOLOGY

Tocilizumab in systemic lupus erythematosus: Data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study

(2010) Gabor G. Illei et al.   ARTHRITIS AND RHEUMATISM

Macrophage depletion decreases IgG anti-DNA in cultures from (NZB · NZW)F1 spleen cells by eliminating the main source of IL-6

(2010) M. E. ALARCÓN-RIQUELME et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

In Vivo Regulation of Bcl6 and T Follicular Helper Cell Development

(2010) A. C. Poholek et al.   JOURNAL OF IMMUNOLOGY

Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus

(2010) N. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-like receptors - sentries in the B-cell response

(2009) Isabelle Bekeredjian-Ding et al.   IMMUNOLOGY

Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH ) cell lineage is induced by IL-12

(2009) Cindy S Ma et al.   IMMUNOLOGY AND CELL BIOLOGY

The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+T cells

(2009) Oliver Dienz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

B7-1/2 (CD80/CD86) Direct Signaling to B Cells Enhances IgG Secretion

(2009) F. C. Rau et al.   JOURNAL OF IMMUNOLOGY

A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice

(2009) J. A. Bubier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE

Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities

(2008) F. Eddahri et al.   BLOOD

TLR7 and CD40 cooperate in IL-6 productionviaenhanced JNK and AP-1 activation

(2008) Tony J. Vanden Bush et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Yaaautoimmune phenotypes are conferred by overexpression of TLR7

(2008) Anna‐Marie Fairhurst et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Toll-like receptor 7–induced naive human B-cell differentiation and immunoglobulin production

(2008) Mark C. Glaum et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Development and characterization of IL-21–producing CD4+T cells

(2008) Akira Suto et al.   JOURNAL OF EXPERIMENTAL MEDICINE