Netrin-1 Reduces Monocyte and Macrophage Chemotaxis towards the Complement Component C5a

Complement system modulation as a target for treatment of arrhythmogenic cardiomyopathy

(2015) Manolis Mavroidis et al.   BASIC RESEARCH IN CARDIOLOGY

Aspirin-induced histone acetylation in endothelial cells enhances synthesis of the secreted isoform of netrin-1 thus inhibiting monocyte vascular infiltration

(2015) Gabriella Passacquale et al.   BRITISH JOURNAL OF PHARMACOLOGY

Netrin-1 as a novel therapeutic target in cardiovascular disease: to activate or inhibit?

(2015) Kerry Layne et al.   CARDIOVASCULAR RESEARCH

Primary Macrophage Chemotaxis Induced by Cannabinoid Receptor 2 Agonists Occurs Independently of the CB2 Receptor

(2015) Lewis Taylor et al.   Scientific Reports

Treatment with the C5a receptor/CD88 antagonist PMX205 reduces inflammation in a murine model of allergic asthma

(2014) Elizabeth B. Staab et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity

(2014) Bhama Ramkhelawon et al.   NATURE MEDICINE

Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief

(2014) Alessio Moriconi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism

(2014) K. Xu et al.   SCIENCE

Endothelial Expression of Guidance Cues in Vessel Wall Homeostasis Dysregulation Under Proatherosclerotic Conditions

(2013) Janine M. van Gils et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria

(2013) Peter Hillmen et al.   BRITISH JOURNAL OF HAEMATOLOGY

Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation

(2013) A. Steffen et al.   JOURNAL OF CELL SCIENCE

Complement in Immune and Inflammatory Disorders: Therapeutic Interventions

(2013) D. Ricklin et al.   JOURNAL OF IMMUNOLOGY

Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic–Uremic Syndrome

(2013) C.M. Legendre et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Real Time Chemotaxis Assay Unveils Unique Migratory Profiles amongst Different Primary Murine Macrophages

(2013) Asif J. Iqbal et al.   PLoS One

Chemotaxis: Movement, direction, control

(2012) A. V. Vorotnikov   BIOCHEMISTRY-MOSCOW

The C5a receptor antagonist PMX205 ameliorates experimentally induced colitis associated with increased IL-4 and IL-10

(2012) U Jain et al.   BRITISH JOURNAL OF PHARMACOLOGY

The first World Cell Race

(2012) Paolo Maiuri et al.   CURRENT BIOLOGY

The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques

(2012) Janine M van Gils et al.   NATURE IMMUNOLOGY

Netrins: versatile extracellular cues with diverse functions

(2011) K. L. W. Sun et al.   DEVELOPMENT

The interaction between different types of activated RAW 264.7 cells and macrophage inflammatory protein-1 alpha

(2011) Zhongshi He et al.   Radiation Oncology

Systemic human Netrin-1 gene delivery by adeno-associated virus type 8 alters leukocyte accumulation and atherogenesis in vivo

(2010) J A Khan et al.   GENE THERAPY

Netrin-1 Regulates Th1/Th2/Th17 Cytokine Production and Inflammation through UNC5B Receptor and Protects Kidney against Ischemia-Reperfusion Injury

(2010) R. K. Tadagavadi et al.   JOURNAL OF IMMUNOLOGY

Netrin-1 Signaling Dampens Inflammatory Peritonitis

(2010) V. Mirakaj et al.   JOURNAL OF IMMUNOLOGY

Chemokine receptors intracellular trafficking

(2010) Elena M. Borroni et al.   PHARMACOLOGY & THERAPEUTICS

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE