Down-Regulation of AKT Signalling by Ursolic Acid Induces Intrinsic Apoptosis and Sensitization to Doxorubicin in Soft Tissue Sarcoma

Pharmacogenomic Characterization of Cytotoxic Compounds from Salvia officinalis in Cancer Cells

(2015) Onat Kadioglu et al.   JOURNAL OF NATURAL PRODUCTS

Current View on the Mechanism of Action of Perifosine in Cancer

(2014) Joachim Fensterle et al.   Anti-Cancer Agents in Medicinal Chemistry

Oleanolic and maslinic acid sensitize soft tissue sarcoma cells to doxorubicin by inhibiting the multidrug resistance protein MRP-1, but not P-glycoprotein

(2014) Victor Hugo Villar et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Molecular Characterization of Synovial Sarcoma in Children and Adolescents: Evidence of Akt Activation

(2014) Fabio Bozzi et al.   Translational Oncology

Ursolic acid in cancer prevention and treatment: Molecular targets, pharmacokinetics and clinical studies

(2013) Muthu K. Shanmugam et al.   BIOCHEMICAL PHARMACOLOGY

SS18-SSX fusion protein-induced Wnt/β-catenin signaling is a therapeutic target in synovial sarcoma

(2013) M Trautmann et al.   ONCOGENE

PI3K Inhibition Enhances Doxorubicin-Induced Apoptosis in Sarcoma Cells

(2013) Diana Marklein et al.   PLoS One

Activation of Ras/PI3K/ERK Pathway Induces c-Myc Stabilization to Upregulate Argininosuccinate Synthetase, Leading to Arginine Deiminase Resistance in Melanoma Cells

(2012) W.-B. Tsai et al.   CANCER RESEARCH

Ursolic acid induces apoptosis in human leukaemia cells and exhibits anti-leukaemic activity in nude mice through the PKB pathway

(2011) Ning Gao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Proliferation-inhibiting and apoptosis-inducing effects of ursolic acid and oleanolic acid on multi-drug resistance cancer cells in vitro

(2011) Jian-zhen Shan et al.   Chinese Journal of Integrative Medicine

Phosphatidylinositol-3′-kinase/AKT signaling is essential in synovial sarcoma

(2010) Nicolaus Friedrichs et al.   INTERNATIONAL JOURNAL OF CANCER

Ursolic Acid, a Pentacyclin Triterpene, Potentiates TRAIL-induced Apoptosis through p53-independent Up-regulation of Death Receptors

(2010) Sahdeo Prasad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ursolic acid, a naturally occurring triterpenoid, suppresses migration and invasion of human breast cancer cells by modulating c-Jun N-terminal kinase, Akt and mammalian target of rapamycin signaling

(2010) Chi-Tai Yeh et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Targeting Inflammatory Pathways by Triterpenoids for Prevention and Treatment of Cancer

(2010) Vivek R. Yadav et al.   Toxins

Downregulation of survivin and activation of caspase-3 through the PI3K/Akt pathway in ursolic acid-induced HepG2 cell apoptosis

(2009) Cong Tang et al.   ANTI-CANCER DRUGS

Phosphorylation of Bcl-2 and activation of caspase-3 via the c-Jun N-terminal kinase pathway in ursolic acid-induced DU145 cells apoptosis

(2009) Yu-xi Zhang et al.   BIOCHIMIE

Pentacyclic Triterpenes of the Lupane, Oleanane and Ursane Group as Tools in Cancer Therapy

(2009) Melanie Laszczyk   PLANTA MEDICA

Endogenous reverse transcriptase as a mediator of ursolic acid’s anti-proliferative and differentiating effects in human cancer cell lines

(2008) Irene Bonaccorsi et al.   CANCER LETTERS

Ursolic acid induces apoptosis by activating p53 and caspase-3 gene expressions and suppressing NF-κB mediated activation of bcl-2 in B16F-10 melanoma cells

(2008) K.A. Manu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY