Intrinsic Tau Acetylation Is Coupled to Auto-Proteolytic Tau Fragmentation

Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss

(2016) Tara E. Tracy et al.   NEURON

Nonenzymatic Protein Acetylation Detected by NAPPA Protein Arrays

(2015) Adam S. Olia et al.   ACS Chemical Biology

Site-Specific Reactivity of Nonenzymatic Lysine Acetylation

(2015) Josue Baeza et al.   ACS Chemical Biology

The twenty-four KDa C-terminal tau fragment increases with aging in tauopathy mice: implications of prion-like properties

(2015) Shin-Ei Matsumoto et al.   HUMAN MOLECULAR GENETICS

Pre-synaptic C-terminal truncated tau is released from cortical synapses in Alzheimer's disease

(2015) Sophie Sokolow et al.   JOURNAL OF NEUROCHEMISTRY

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

(2015) Sang-Won Min et al.   NATURE MEDICINE

Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice

(2015) Meaghan Morris et al.   NATURE NEUROSCIENCE

TheXanthomonas campestrisType III Effector XopJ Proteolytically Degrades Proteasome Subunit RPT6

(2015) Suayib Üstün et al.   PLANT PHYSIOLOGY

Toxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups

(2015) Yoshiyuki Soeda et al.   Nature Communications

Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau

(2015) Katja Hochgräfe et al.   Acta Neuropathologica Communications

Nuclear Magnetic Resonance Analysis of the Acetylation Pattern of the Neuronal Tau Protein

(2014) Amina Kamah et al.   BIOCHEMISTRY

Divergent CSF   alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy

(2014) D. Wagshal et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Structural Insight into Tau Protein’s Paradox of Intrinsically Disordered Behavior, Self-Acetylation Activity, and Aggregation

(2014) Yin Luo et al.   Journal of Physical Chemistry Letters

Mechanistic Basis of Phenothiazine-Driven Inhibition of Tau Aggregation

(2013) Elias Akoury et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mitochondrial protein acetylation as a cell-intrinsic, evolutionary driver of fat storage: Chemical and metabolic logic of acetyl-lysine modifications

(2013) Sirisha Ghanta et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Aminothienopyridazines and Methylene Blue Affect Tau Fibrillization via Cysteine Oxidation

(2013) Alex Crowe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Widespread and Enzyme-independentNϵ-Acetylation andNϵ-Succinylation of Proteins in the Chemical Conditions of the Mitochondrial Matrix

(2013) Gregory R. Wagner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The microtubule-associated tau protein has intrinsic acetyltransferase activity

(2013) Todd J Cohen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterization of Novel CSF Tau and ptau Biomarkers for Alzheimer’s Disease

(2013) Jere E. Meredith Jr. et al.   PLoS One

Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo

(2012) Erin E. Congdon et al.   Autophagy

Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies

(2012) David J. Irwin et al.   BRAIN

Autoacetylation of the MYST Lysine Acetyltransferase MOF Protein

(2012) Chao Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Function of the Active Site Lysine Autoacetylation in Tip60 Catalysis

(2012) Chao Yang et al.   PLoS One

Methylene Blue Reduced Abnormal Tau Accumulation in P301L Tau Transgenic Mice

(2012) Masato Hosokawa et al.   PLoS One

Serine/threonine acetylation of TGF -activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling

(2012) N. Paquette et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulations of hMOF autoacetylation by SIRT1 regulate hMOF recruitment and activities on the chromatin

(2011) Lu Lu et al.   CELL RESEARCH

MYST protein acetyltransferase activity requires active site lysine autoacetylation

(2011) Hua Yuan et al.   EMBO JOURNAL

The YopJ superfamily in plant-associated bacteria

(2011) JENNIFER D. LEWIS et al.   MOLECULAR PLANT PATHOLOGY

“Lest we forget you — methylene blue …”

(2011) R. Heiner Schirmer et al.   NEUROBIOLOGY OF AGING

The acetylation of tau inhibits its function and promotes pathological tau aggregation

(2011) Todd J. Cohen et al.   Nature Communications

SIRT1 Regulates Autoacetylation and Histone Acetyltransferase Activity of TIP60

(2010) Jiadong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Acetyltransferase Activity of the Bacterial Toxin YopJ ofYersiniaIs Activated by Eukaryotic Host Cell Inositol Hexakisphosphate

(2010) Rohit Mittal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden

(2010) John C O'Leary et al.   Molecular Neurodegeneration

Cleavage of Tau by calpain in Alzheimer's disease: the quest for the toxic 17 kD fragment

(2010) Sarika Garg et al.   NEUROBIOLOGY OF AGING

Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

(2010) Sang-Won Min et al.   NEURON

Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

(2009) Yipeng Wang et al.   HUMAN MOLECULAR GENETICS

Identification and Verification of Lysine Propionylation and Butyrylation in Yeast Core Histones Using PTMap Software

(2009) Kai Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Direct analysis of tau from PSP brain identifies new phosphorylation sites and a major fragment of N-terminally cleaved tau containing four microtubule-binding repeats

(2008) Selina Wray et al.   JOURNAL OF NEUROCHEMISTRY

Molecular Characterization of Propionyllysines in Non-histone Proteins

(2008) Zhongyi Cheng et al.   MOLECULAR & CELLULAR PROTEOMICS