EGFR Activation Leads to Cell Death Independent of PI3K/AKT/mTOR in an AD293 Cell Line

Nutrient withdrawal rescues growth factor-deprived cells from mTOR-dependent damage

(2016) Emiliano Panieri et al.   Aging-US

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

MicroRNAs Are Part of the Regulatory Network that Controls EGF Induced Apoptosis, Including Elements of the JAK/STAT Pathway, in A431 Cells

(2015) Ibrahim Alanazi et al.   PLoS One

The Failure in the Stabilization of Glioblastoma-Derived Cell Lines: Spontaneous In Vitro Senescence as the Main Culprit

(2014) Ewelina Stoczynska-Fidelus et al.   PLoS One

Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks

(2014) Sharmistha Chakraborty et al.   Nature Communications

Targeting PI3K/Akt/mTOR Signaling in Cancer

(2014) Camillo Porta et al.   Frontiers in Oncology

Combined gene expression and proteomic analysis of EGF induced apoptosis in A431 cells suggests multiple pathways trigger apoptosis

(2013) Ibrahim Alanazi et al.   APOPTOSIS

EGFR Phosphorylates Tumor-Derived EGFRvIII Driving STAT3/5 and Progression in Glioblastoma

(2013) Qi-Wen Fan et al.   CANCER CELL

Asymmetric kinase dimer formation is crucial for the activation of oncogenic EGFRvIII but not for ERBB3 phosphorylation

(2013) Rama Kancha et al.   Cell Communication and Signaling

Threshold-controlled ubiquitination of the EGFR directs receptor fate

(2013) Sara Sigismund et al.   EMBO JOURNAL

Endocytosis of EGFR requires its kinase activity and N-terminal transmembrane dimerization motif

(2013) R. Heukers et al.   JOURNAL OF CELL SCIENCE

Emerging landscape of oncogenic signatures across human cancers

(2013) Giovanni Ciriello et al.   NATURE GENETICS

EGFR wild type antagonizes EGFRvIII-mediated activation of Met in glioblastoma

(2013) L Li et al.   ONCOGENE

An EGFR wild type–EGFRvIII–HB-EGF feed-forward loop regulates the activation of EGFRvIII

(2013) L Li et al.   ONCOGENE

Screening for EGFR Amplifications with a Novel Method and Their Significance for the Outcome of Glioblastoma Patients

(2013) Michał Bieńkowski et al.   PLoS One

Nuclear EGFRvIII-STAT5b complex contributes to glioblastoma cell survival by direct activation of the Bcl-XL promoter

(2012) Khatri Latha et al.   INTERNATIONAL JOURNAL OF CANCER

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

EGFR-AKT-Smad Signaling Promotes Formation of Glioma Stem-like Cells and Tumor Angiogenesis by ID3-Driven Cytokine Induction

(2011) X. Jin et al.   CANCER RESEARCH

Endosomal Accumulation of the Activated Epidermal Growth Factor Receptor (EGFR) Induces Apoptosis

(2011) Jamie S. Rush et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glioma Specific Extracellular Missense Mutations in the First Cysteine Rich Region of Epidermal Growth Factor Receptor (EGFR) Initiate Ligand Independent Activation

(2011) Susie I. Ymer et al.   Cancers

EGFR–PI3K–AKT–mTOR signaling in head and neck squamous cell carcinomas: attractive targets for molecular-oriented therapy

(2010) Christian Freudlsperger et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

Cellular localization of the activated EGFR determines its effect on cell growth in MDA-MB-468 cells

(2008) Dustin C. Hyatt et al.   EXPERIMENTAL CELL RESEARCH

Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression

(2008) Liang-Yi Hung et al.   NUCLEIC ACIDS RESEARCH