Novel Acylguanidine Derivatives Targeting Smoothened Induce Antiproliferative and Pro-Apoptotic Effects in Chronic Myeloid Leukemia Cells

Title
Novel Acylguanidine Derivatives Targeting Smoothened Induce Antiproliferative and Pro-Apoptotic Effects in Chronic Myeloid Leukemia Cells
Authors
Keywords
Hedgehog signaling, Apoptosis, MicroRNAs, Small interfering RNAs, RNA isolation, Protein expression, RNA synthesis, Cancer treatment
Journal
PLoS One
Volume 11, Issue 3, Pages e0149919
Publisher
Public Library of Science (PLoS)
Online
2016-03-03
DOI
10.1371/journal.pone.0149919

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