Side-Effects of Irinotecan (CPT-11), the Clinically Used Drug for Colon Cancer Therapy, Are Eliminated in Experimental Animals Treated with Latex Proteins fromCalotropis procera(Apocynaceae)

Crystal structure of an antifungal osmotin-like protein from Calotropis procera and its effects on Fusarium solani spores, as revealed by atomic force microscopy: Insights into the mechanism of action

(2015) Marcio V. Ramos et al.   PHYTOCHEMISTRY

The Adaptor Protein Myd88 Is a Key Signaling Molecule in the Pathogenesis of Irinotecan-Induced Intestinal Mucositis

(2015) Deysi V. T. Wong et al.   PLoS One

Targeted inhibition of IL-18 attenuates irinotecan-induced intestinal mucositis in mice

(2014) R C P Lima-Júnior et al.   BRITISH JOURNAL OF PHARMACOLOGY

Diarrhoea due to small bowel diseases

(2013) Joseph A. Murray et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Protein fraction of Calotropis procera latex protects against 5-fluorouracil-induced oral mucositis associated with downregulation of pivotal pro-inflammatory mediators

(2013) Ana Paula F. Freitas et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Identification of a Novel Calotropis procera Protein That Can Suppress Tumor Growth in Breast Cancer through the Suppression of NF-κB Pathway

(2012) Ramar Perumal Samy et al.   PLoS One

Management of oral and gastrointestinal mucositis: ESMO Clinical Practice Guidelines

(2011) D. E. Peterson et al.   ANNALS OF ONCOLOGY

Involvement of nitric oxide on the pathogenesis of irinotecan-induced intestinal mucositis: role of cytokines on inducible nitric oxide synthase activation

(2011) Roberto César P. Lima-Júnior et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Osmotin purified from the latex of Calotropis procera: Biochemical characterization, biological activity and role in plant defense

(2011) Cleverson Diniz Teixeira de Freitas et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

The defensive role of latex in plants: detrimental effects on insects

(2010) Márcio V. Ramos et al.   Arthropod-Plant Interactions

In vivo growth inhibition of sarcoma 180 by latex proteins from Calotropis procera

(2010) Jefferson S. Oliveira et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Current place of high-dose irinotecan chemotherapy in patients with metastatic colorectal cancer

(2009) Mohamed Hebbar et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Involvement of NO in the inhibitory effect of Calotropis procera latex protein fractions on leukocyte rolling, adhesion and infiltration in rat peritonitis model

(2009) Márcio V. Ramos et al.   JOURNAL OF ETHNOPHARMACOLOGY

Chemotherapy-induced diarrhoea

(2009) Rachel J Gibson et al.   Current Opinion in Supportive and Palliative Care

Early molecular and functional changes in colonic epithelium that precede increased gut permeability during colitis development in mdr1a(−/−) mice

(2008) Andrew Collett et al.   INFLAMMATORY BOWEL DISEASES