The Adaptor Protein Myd88 Is a Key Signaling Molecule in the Pathogenesis of Irinotecan-Induced Intestinal Mucositis

TLR Signaling Modulates Side Effects of Anticancer Therapy in the Small Intestine

(2015) Magdalena Frank et al.   JOURNAL OF IMMUNOLOGY

Involvement of nuclear factor kappa B in the maintenance of persistent inflammatory hypernociception

(2015) Guilherme R. Souza et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Inflammasome Activation Is Reactive Oxygen Species Dependent and Mediates Irinotecan-Induced Mucositis through IL-1β and IL-18 in Mice

(2014) Raquel D.N. Arifa et al.   AMERICAN JOURNAL OF PATHOLOGY

Targeted inhibition of IL-18 attenuates irinotecan-induced intestinal mucositis in mice

(2014) R C P Lima-Júnior et al.   BRITISH JOURNAL OF PHARMACOLOGY

The TLR and IL-1 signalling network at a glance

(2014) P. Cohen   JOURNAL OF CELL SCIENCE

Guidance on the management of diarrhoea during cancer chemotherapy

(2014) Jervoise Andreyev et al.   LANCET ONCOLOGY

Glutamine attenuates the inhibitory effect of methotrexate on TLR signaling during intestinal chemotherapy-induced mucositis in a rat

(2014) Igor Sukhotnik et al.   Nutrition & Metabolism

Cutting Edge: TLR Signaling Licenses IRAK1 for Rapid Activation of the NLRP3 Inflammasome

(2013) T. Fernandes-Alnemri et al.   JOURNAL OF IMMUNOLOGY

Innate immunity in the small intestine

(2012) Rebeca Santaolalla et al.   CURRENT OPINION IN GASTROENTEROLOGY

5-Fluorouracil Induced Intestinal Mucositis via Nuclear Factor-κB Activation by Transcriptomic Analysis and In Vivo Bioluminescence Imaging

(2012) Chung-Ta Chang et al.   PLoS One

Systematic review of agents for the management of gastrointestinal mucositis in cancer patients

(2012) Rachel J. Gibson et al.   SUPPORTIVE CARE IN CANCER

Toll-Like Receptor–Gut Microbiota Interactions: Perturb at Your Own Risk!

(2011) Frederic A. Carvalho et al.   Annual Review of Physiology

Involvement of nitric oxide on the pathogenesis of irinotecan-induced intestinal mucositis: role of cytokines on inducible nitric oxide synthase activation

(2011) Roberto César P. Lima-Júnior et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Severity of doxorubicin-induced small intestinal mucositis is regulated by the TLR-2 and TLR-9 pathways

(2011) Agnieszka Kaczmarek et al.   JOURNAL OF PATHOLOGY

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Peptidoglycan enhances proinflammatory cytokine expression through the TLR2 receptor, MyD88, phosphatidylinositol 3-kinase/AKT and NF-kappaB pathways in BV-2 microglia

(2010) Hsiao-Yun Lin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Irinotecan Injures Tight Junction and Causes Bacterial Translocation in Rat

(2010) Toshihiro Nakao et al.   JOURNAL OF SURGICAL RESEARCH

Targeting TLR/IL-1R Signalling in Human Diseases

(2010) Maria Loiarro et al.   MEDIATORS OF INFLAMMATION

The Role of Intestinal Microbiota in the Development and Severity of Chemotherapy-Induced Mucositis

(2010) Michel J. van Vliet et al.   PLoS Pathogens

Irinotecan and its active metabolite, SN-38: review of bioanalytical methods and recent update from clinical pharmacology perspectives

(2009) Mullangi Ramesh et al.   BIOMEDICAL CHROMATOGRAPHY

Toll-like receptors (TLRs) and Nod-like receptors (NLRs) in inflammatory disorders

(2009) Masayuki Fukata et al.   SEMINARS IN IMMUNOLOGY