Over-expression ofDXSgene enhances terpenoidal secondary metabolite accumulation in rose-scented geranium andWithania somnifera: active involvement of plastid isoprenogenic pathway in their biosynthesis

Targeting Plasmodium Metabolism to Improve Antimalarial Drug Design

(2016) Claudia Avitia-Domínguez et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Enhanced Diterpene Tanshinone Accumulation and Bioactivity of Transgenic Salvia miltiorrhiza Hairy Roots by Pathway Engineering

(2016) Min Shi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Differential Subplastidial Localization and Turnover of Enzymes Involved in Isoprenoid Biosynthesis in Chloroplasts

(2016) Catalina Perello et al.   PLoS One

RNAi and Homologous Over-Expression Based Functional Approaches Reveal Triterpenoid Synthase Gene-Cycloartenol Synthase Is Involved in Downstream Withanolide Biosynthesis in Withania somnifera

(2016) Smrati Mishra et al.   PLoS One

Genotype independent and efficient Agrobacterium-mediated genetic transformation of the medicinal plant Withania somnifera Dunal

(2015) Smrati Mishra et al.   JOURNAL OF PLANT BIOCHEMISTRY AND BIOTECHNOLOGY

Light and auxin responsive cytochrome P450s from Withania somnifera Dunal: cloning, expression and molecular modelling of two pairs of homologue genes with differential regulation

(2015) Sudhakar Srivastava et al.   PROTOPLASMA

Comparative transcripts profiling of fruit mesocarp and endocarp relevant to secondary metabolism by suppression subtractive hybridization in Azadirachta indica (neem)

(2014) Lokesh K. Narnoliya et al.   MOLECULAR BIOLOGY REPORTS

Deoxyxylulose 5-Phosphate Synthase Controls Flux through the Methylerythritol 4-Phosphate Pathway in Arabidopsis

(2014) L. P. Wright et al.   PLANT PHYSIOLOGY

De novo sequencing and assembly of Centella asiatica leaf transcriptome for mapping of structural, functional and regulatory genes with special reference to secondary metabolism

(2013) Rajender S. Sangwan et al.   GENE

Changes in growth, essential oil yield and composition of geranium (Pelargonium graveolensL.) as affected by growing media

(2013) Abdolhossein Rezaei Nejad et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

The role of 1-deoxy-d-xylulose-5-phosphate synthase and phytoene synthase gene family in citrus carotenoid accumulation

(2013) Gang Peng et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Effect of gibberellic acid and calliterpenone on plant growth attributes, trichomes, essential oil biosynthesis and pathway gene expression in differential manner in Mentha arvensis L

(2013) Subir K. Bose et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Effect of prolonged water stress on specialized secondary metabolites, peltate glandular trichomes, and pathway gene expression in Artemisia annua L.

(2013) Ritesh K. Yadav et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Tropine Forming Tropinone Reductase Gene from Withania somnifera (Ashwagandha): Biochemical Characteristics of the Recombinant Enzyme and Novel Physiological Overtones of Tissue-Wide Gene Expression Patterns

(2013) Amit Kumar Kushwaha et al.   PLoS One

MEGA-CC: computing core of molecular evolutionary genetics analysis program for automated and iterative data analysis

(2012) S. Kumar et al.   BIOINFORMATICS

Metabolic profiling of the methylerythritol phosphate pathway reveals the source of post-illumination isoprene burst from leaves

(2012) ZIRU LI et al.   PLANT CELL AND ENVIRONMENT

Withanolide biosynthesis recruits both mevalonate and DOXP pathways of isoprenogenesis in Ashwagandha Withania somnifera L. (Dunal)

(2012) Narayan D. Chaurasiya et al.   PLANT CELL REPORTS

Efficient genetic transformation of Withania coagulans (Stocks) Dunal mediated by Agrobacterium tumefaciens from leaf explants of in vitro multiple shoot culture

(2012) Smrati Mishra et al.   PROTOPLASMA

Cloning and functional characterization of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene from Withania somnifera: an important medicinal plant

(2012) Nehal Akhtar et al.   PROTOPLASMA

Qualitative and quantitative variations in withanolides and expression of some pathway genes during different stages of morphogenesis in Withania somnifera Dunal

(2012) Farzana Sabir et al.   PROTOPLASMA

Biochemistry of the non-mevalonate isoprenoid pathway

(2011) Tobias Gräwert et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Isoprenoid Precursor Biosynthesis Offers Potential Targets for Drug Discovery Against Diseases Caused by Apicomplexan Parasites

(2011) William N. Hunter   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Functional characterization of the three genes encoding 1-deoxy-D-xylulose 5-phosphate synthase in maize

(2011) E. Cordoba et al.   JOURNAL OF EXPERIMENTAL BOTANY

Functional effect of grapevine 1-deoxy-D-xylulose 5-phosphate synthase substitution K284N on Muscat flavour formation

(2011) Juri Battilana et al.   JOURNAL OF EXPERIMENTAL BOTANY

Analysis of 1-deoxy-d-xylulose 5-phosphate synthase activity in Grey poplar leaves using isotope ratio mass spectrometry

(2010) Andrea Ghirardo et al.   PHYTOCHEMISTRY

Effects of exogenous methyl jasmonate on artemisinin biosynthesis and secondary metabolites in Artemisia annua L.

(2009) Huahong Wang et al.   INDUSTRIAL CROPS AND PRODUCTS

Identification and characterization of class 1 DXS gene encoding 1-deoxy-d-xylulose-5-phosphate synthase, the first committed enzyme of the MEP pathway from soybean

(2008) Man Zhang et al.   MOLECULAR BIOLOGY REPORTS

Withanolide A is inherently de novo biosynthesized in roots of the medicinal plant Ashwagandha (Withania somnifera)

(2008) Rajender Singh Sangwan et al.   PHYSIOLOGIA PLANTARUM

Chloroplast localization of methylerythritol 4-phosphate pathway enzymes and regulation of mitochondrial genes in ispD and ispE albino mutants in Arabidopsis

(2008) Ming-Hsiun Hsieh et al.   PLANT MOLECULAR BIOLOGY

The plastidial MEP pathway: unified nomenclature and resources

(2008) M PHILLIPS et al.   TRENDS IN PLANT SCIENCE

Analysis of withanolides in root and leaf ofWithania somnifera by HPLC with photodiode array and evaporative light scattering detection

(2007) Narayan Das Chaurasiya et al.   PHYTOCHEMICAL ANALYSIS