Bringing It All Together: Coupling Excision Repair to the DNA Damage Checkpoint

Mechanisms of DNA Repair by Photolyase and Excision Nuclease (Nobel Lecture)

(2016) Aziz Sancar   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

ATR Kinase Inhibition Protects Non-cycling Cells from the Lethal Effects of DNA Damage and Transcription Stress

(2016) Michael G. Kemp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling

(2015) Laura A Lindsey-Boltz et al.   CELL CYCLE

Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Definedin VitroSystem

(2014) Laura A. Lindsey-Boltz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Formation ofArabidopsisCryptochrome 2 Photobodies in Mammalian Nuclei

(2013) Irem Ozkan-Dagliyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Role for the Replication Protein Treslin (Ticrr) in the ATR Kinase-mediated Checkpoint Response

(2013) Bachar H. Hassan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In VitroAnalysis of the Role of Replication Protein A (RPA) and RPA Phosphorylation in ATR-mediated Checkpoint Signaling

(2012) Laura A. Lindsey-Boltz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA

(2011) Michael G. Kemp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tethering DNA Damage Checkpoint Mediator Proteins Topoisomerase IIβ-binding Protein 1 (TopBP1) and Claspin to DNA Activates Ataxia-Telangiectasia Mutated and RAD3-related (ATR) Phosphorylation of Checkpoint Kinase 1 (Chk1)

(2011) Laura A. Lindsey-Boltz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation

(2011) S. Sertic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress

(2010) Michael G. Kemp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exo1 Competes with Repair Synthesis, Converts NER Intermediates to Long ssDNA Gaps, and Promotes Checkpoint Activation

(2010) Michele Giannattasio et al.   MOLECULAR CELL

Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling

(2010) J.-H. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long Patch Base Excision Repair Proceeds via Coordinated Stimulation of the Multienzyme DNA Repair Complex

(2009) Lata Balakrishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reconstitution of Human Claspin-mediated Phosphorylation of Chk1 by the ATR (Ataxia Telangiectasia-mutated and Rad3-related) Checkpoint Kinase

(2009) Laura A. Lindsey-Boltz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The human ATR-mediated DNA damage checkpoint in a reconstituted system

(2009) Jun-Hyuk Choi et al.   METHODS

Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA

(2009) J.-H. Choi et al.   NUCLEIC ACIDS RESEARCH

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY