YM155, a small molecule inhibitor of survivin expression, sensitizes cancer cells to hypericin-mediated photodynamic therapy

Quantitative Proteomic Analysis of Cellular Resistance to the Nanoparticle Abraxane

(2015) Minzhi Zhao et al.   ACS Nano

MicroRNA-181a regulates epithelial-mesenchymal transition by targeting PTEN in drug-resistant lung adenocarcinoma cells

(2015) HAIHUI LI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Delivery of tumor-homing TRAIL sensitizer with long-acting TRAIL as a therapy for TRAIL-resistant tumors

(2015) Yumin Oh et al.   JOURNAL OF CONTROLLED RELEASE

Examination of survivin expression in 50 chordoma specimens-A histological and in vitro study

(2015) Elke V. Froehlich et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

MicroRNA-522 reverses drug resistance of doxorubicin-induced HT29 colon cancer cell by targeting ABCB5

(2015) GE YANG et al.   Molecular Medicine Reports

Cell death by autophagy: emerging molecular mechanisms and implications for cancer therapy

(2015) S Fulda et al.   ONCOGENE

Antitumor activity of YM155, a selective survivin suppressant, in combination with cisplatin in hepatoblastoma

(2015) YING YU et al.   ONCOLOGY REPORTS

Photodynamic efficiency of hypericin compared with chlorin and hematoporphyrin derivatives in HEp-2 and Vero epithelial cell lines

(2015) Claudia Bernal et al.   Photodiagnosis and Photodynamic Therapy

An increase in glucosylceramide synthase induces Bcl-xL-mediated cell survival in vinorelbine-resistant lung adenocarcinoma cells

(2015) Wei-Hsin Chiu et al.   Oncotarget

PKM2 Subcellular Localization Is Involved in Oxaliplatin Resistance Acquisition in HT29 Human Colorectal Cancer Cell Lines

(2015) Alba Ginés et al.   PLoS One

YM155 sensitizes triple-negative breast cancer to membrane-bound TRAIL through p38 MAPK- and CHOP-mediated DR5 upregulation

(2014) Marzia Pennati et al.   INTERNATIONAL JOURNAL OF CANCER

Markedly additive antitumor activity with the combination of a selective survivin suppressant YM155 and alemtuzumab in adult T-cell leukemia

(2013) J. Chen et al.   BLOOD

Treat cancers by targeting survivin: Just a dream or future reality?

(2013) Mohane Selvaraj Coumar et al.   CANCER TREATMENT REVIEWS

YM155 sensitizes ovarian cancer cells to cisplatin inducing apoptosis and tumor regression

(2013) Roser Mir et al.   GYNECOLOGIC ONCOLOGY

Conjunction of glutathione level, NAD(P)H/FAD redox status and hypericin content as a potential factor affecting colon cancer cell resistance to photodynamic therapy with hypericin

(2013) Lucia Mikešová et al.   Photodiagnosis and Photodynamic Therapy

Molecular Response to Hypericin-Induced Photodamage

(2012) B. Krammer et al.   CURRENT MEDICINAL CHEMISTRY

Cytoprotective Signaling Associated with Nitric Oxide Upregulation in Tumor Cells Subjected to Photodynamic Therapy-like Oxidative Stress

(2012) Reshma Bhowmick et al.   FREE RADICAL BIOLOGY AND MEDICINE

The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

(2012) Mar Carmena et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Mechanisms of Resistance to Photodynamic Therapy

(2011) A. Casas et al.   CURRENT MEDICINAL CHEMISTRY

Optimization of photodynamic therapy response by survivin gene knockdown in human metastatic breast cancer T47D cells

(2011) Ingrid S. Cogno et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

(2011) Ronan J Kelly et al.   Molecular Cancer

In vitro photochemical and phototoxicological characterization of major constituents in St. John’s Wort (Hypericum perforatum) extracts

(2011) Satomi Onoue et al.   PHYTOCHEMISTRY

Marked anti-tumour activity of the combination of YM155, a novel survivin suppressant and platinum-based drugs

(2010) T Iwasa et al.   BRITISH JOURNAL OF CANCER

Broad spectrum and potent antitumor activities of YM155, a novel small-molecule survivin suppressant, in a wide variety of human cancer cell lines and xenograft models

(2010) Takahito Nakahara et al.   CANCER SCIENCE

Hypericins as Potential Leads for New Therapeutics

(2010) Anastasia Karioti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cellular and Molecular Mechanisms of Photodynamic Hypericin Therapy for Nasopharyngeal Carcinoma Cells

(2010) X. Wang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Gambogic acid, a potent inhibitor of survivin, reverses docetaxel resistance in gastric cancer cells

(2008) Tingting Wang et al.   CANCER LETTERS