Clinical Decision Support Tools: The Evolution of a Revolution

Pharmacokinetic Features and Presence of Antidrug Antibodies Associate With Response to Infliximab Induction Therapy in Patients With Moderate to Severe Ulcerative Colitis

(2016) Johannan F. Brandse et al.   Clinical Gastroenterology and Hepatology

An Accelerated Infliximab Induction Regimen Reduces the Need for Early Colectomy in Patients With Acute Severe Ulcerative Colitis

(2015) David J. Gibson et al.   Clinical Gastroenterology and Hepatology

Therapeutic drug monitoring of monoclonal antibodies in inflammatory and malignant disease: Translating TNF-α experience to oncology

(2015) TH Oude Munnink et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Loss of Infliximab Into Feces Is Associated With Lack of Response to Therapy in Patients With Severe Ulcerative Colitis

(2015) Johannan F. Brandse et al.   GASTROENTEROLOGY

Proteolytic Cleavage and Loss of Function of Biologic Agents That Neutralize Tumor Necrosis Factor in the Mucosa of Patients With Inflammatory Bowel Disease

(2015) Paolo Biancheri et al.   GASTROENTEROLOGY

Dashboard Systems: Implementing Pharmacometrics from Bench to Bedside

(2014) Diane R. Mould et al.   AAPS Journal

Individualization of Piperacillin Dosing for Critically Ill Patients: Dosing Software To Optimize Antimicrobial Therapy

(2014) T. W. Felton et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Review of therapeutic drug monitoring of anticancer drugs part two – Targeted therapies

(2014) Nicolas Widmer et al.   EUROPEAN JOURNAL OF CANCER

Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions

(2014) Jason A Roberts et al.   LANCET INFECTIOUS DISEASES

Impact of trough serum level on radiographic and clinical response to infliximab plus methotrexate in patients with rheumatoid arthritis: results from the RISING study

(2014) Tsutomu Takeuchi et al.   Modern Rheumatology

Software for Dosage Individualization of Voriconazole for Immunocompromised Patients

(2013) William W. Hope et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Are Vancomycin Trough Concentrations Adequate for Optimal Dosing?

(2013) Michael N. Neely et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Improved accuracy of anticoagulant dose prediction using a pharmacogenetic and artificial neural network-based method

(2013) Hussain A. Isma’eel et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Individualised therapy is more cost-effective than dose intensification in patients with Crohn’s disease who lose response to anti-TNF treatment: a randomised, controlled trial

(2013) Casper Steenholdt et al.   GUT

Contribution of Renal and Non-Renal Clearance on Increased Total Clearance of Adalimumab in Glomerular Disease

(2013) Brittney V. Roberts et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Effect of Treatment Regimen on the Immunogenicity of Human Interferon Beta in Immune Tolerant Mice

(2013) Grzegorz Kijanka et al.   PHARMACEUTICAL RESEARCH

Intravenous phenytoin: a retrospective analysis of Bayesian forecasting versus conventional dosing in patients

(2013) Andrea Tobler et al.   International Journal of Clinical Pharmacy

A Bayesian Dose-Individualization Method for Warfarin

(2012) Daniel F. B. Wright et al.   CLINICAL PHARMACOKINETICS

Benchmarking Therapeutic Drug Monitoring Software: A Review of Available Computer Tools

(2012) Aline Fuchs et al.   CLINICAL PHARMACOKINETICS

Anti-TNF Monoclonal Antibodies in Inflammatory Bowel Disease: Pharmacokinetics-Based Dosing Paradigms

(2012) I Ordás et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Effect of antigen binding affinity and effector function on the pharmacokinetics and pharmacodynamics of anti-IgE monoclonal antibodies

(2012) Deborah L. Mortensen et al.   mAbs

Rational development and utilization of antibody-based therapeutic proteins in pediatrics

(2012) Zhenhua Xu et al.   PHARMACOLOGY & THERAPEUTICS

Loss of Response and Need for Adalimumab Dose Intensification in Crohn's Disease: A Systematic Review

(2011) Vincent Billioud et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Defining Health Information Technology–Related Errors

(2011) Dean F. Sittig   ARCHIVES OF INTERNAL MEDICINE

Artificial neural networks for closed loop control of in silico and ad hoc type 1 diabetes

(2011) J. Fernandez de Canete et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Neural Network-Based Real-Time Prediction of Glucose in Patients with Insulin-Dependent Diabetes

(2011) Scott M. Pappada et al.   Diabetes Technology & Therapeutics

Adalimumab Induces and Maintains Clinical Remission in Patients With Moderate-to-Severe Ulcerative Colitis

(2011) William J. Sandborn et al.   GASTROENTEROLOGY

Development of Antidrug Antibodies Against Adalimumab and Association With Disease Activity and Treatment Failure During Long-term Follow-up

(2011) Geertje M. Bartelds   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Immunogenicity of Therapeutic Proteins: The Use of Animal Models

(2011) Vera Brinks et al.   PHARMACEUTICAL RESEARCH

Evaluating Performance of a Decision Support System to Improve Methotrexate Pharmacotherapy in Children and Young Adults With Cancer

(2011) Erin Dombrowsky et al.   THERAPEUTIC DRUG MONITORING

Optimal Design of Pharmacokinetic Studies

(2010) Leon Aarons et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Pharmacokinetics and Pharmacodynamics of Monoclonal Antibodies

(2010) Diane R. Mould et al.   BIODRUGS

Computerized Decision Support for EPO Dosing in Hemodialysis Patients

(2009) Dana C. Miskulin et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Anti-infliximab and anti-adalimumab antibodies in relation to response to adalimumab in infliximab switchers and anti-tumour necrosis factor naive patients: a cohort study

(2009) G. M. Bartelds et al.   ANNALS OF THE RHEUMATIC DISEASES

Review: Predicting response to anti-TNF agents for the treatment of Crohn's disease

(2009) Corey A. Siegel et al.   Therapeutic Advances in Gastroenterology

Integration of modeling and simulation into hospital-based decision support systems guiding pediatric pharmacotherapy

(2008) Jeffrey S Barrett et al.   BMC Medical Informatics and Decision Making

Efficacy and Safety of Tumor Necrosis Factor Antagonists in Crohn's Disease: Meta-Analysis of Placebo-Controlled Trials

(2008) Laurent Peyrin–Biroulet et al.   Clinical Gastroenterology and Hepatology

Monoclonal Antibody Pharmacokinetics and Pharmacodynamics

(2008) W Wang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS