The inhibition of voltage-gated H+ channel (HVCN1) induces acidification of leukemic Jurkat T cells promoting cell death by apoptosis

Voltage-Gated Proton Channel in Human Glioblastoma Multiforme Cells

(2016) Luisa Ribeiro-Silva et al.   ACS Chemical Neuroscience

Na + /H + antiporter (NHE1) and lactate/H + symporters (MCTs) in pH homeostasis and cancer metabolism

(2016) Laurent Counillon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Parameters Influencing Zinc in Experimental Systems in Vivo and in Vitro

(2016) Johanna Ollig et al.   Metals

Voltage-Gated Proton Channels as Novel Drug Targets: From NADPH Oxidase Regulation to Sperm Biology

(2015) Tamara Seredenina et al.   ANTIOXIDANTS & REDOX SIGNALING

Proton channels and exchangers in cancer

(2015) Enrico Pierluigi Spugnini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity

(2015) Adam P. Levine et al.   PLoS One

Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives

(2014) Liang Hong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zn2+ induces apoptosis in human highly metastatic SHG-44 glioma cells, through inhibiting activity of the voltage-gated proton channel Hv1

(2013) Yifan Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular mechanism of voltage sensing in voltage-gated proton channels

(2013) Carlos Gonzalez et al.   JOURNAL OF GENERAL PHYSIOLOGY

Subunit Interactions during Cooperative Opening of Voltage-Gated Proton Channels

(2013) Feng Qiu et al.   NEURON

Human Voltage-Gated Proton Channel Hv1: A New Potential Biomarker for Diagnosis and Prognosis of Colorectal Cancer

(2013) Yifan Wang et al.   PLoS One

Autoimmune disorder phenotypes inHvcn1-deficient mice

(2012) Mari Sasaki et al.   BIOCHEMICAL JOURNAL

Targeting Ion Channels in Leukemias: A New Challenge for Treatment

(2012) A. Arcangeli et al.   CURRENT MEDICINAL CHEMISTRY

Clinicopathological and Biological Significance of Human Voltage-gated Proton Channel Hv1 Protein Overexpression in Breast Cancer

(2012) Yifan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zinc-mediated Allosteric Inhibition of Caspase-6

(2012) Elih M. Velázquez-Delgado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of zinc-mediated inhibition of caspase-9

(2012) Kristen L. Huber et al.   PROTEIN SCIENCE

Specific expression of the human voltage-gated proton channel Hv1 in highly metastatic breast cancer cells, promotes tumor progression and metastasis

(2011) Yifan Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Aspartate 112 is the selectivity filter of the human voltage-gated proton channel

(2011) Boris Musset et al.   NATURE

Acid Extrusion from Human Spermatozoa Is Mediated by Flagellar Voltage-Gated Proton Channel

(2010) Polina V. Lishko et al.   CELL

Targeting the Warburg effect in hematological malignancies: from PET to therapy

(2010) Mala Shanmugam et al.   CURRENT OPINION IN ONCOLOGY

HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species

(2010) Melania Capasso et al.   NATURE IMMUNOLOGY

Molecular and Functional Characterization of Hv1 Proton Channel in Human Granulocytes

(2010) Gábor L. Petheő et al.   PLoS One

VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification

(2009) Antoun El Chemaly et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst

(2009) I. S. Ramsey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Voltage-gated proton channels

(2008) T. E. DeCoursey   CELLULAR AND MOLECULAR LIFE SCIENCES