The unique electrical properties in an extracellular fluid of the mammalian cochlea; their functional roles, homeostatic processes, and pathological significance

A mutation in SLC22A4 encoding an organic cation transporter expressed in the cochlea strial endothelium causes human recessive non-syndromic hearing loss DFNB60

(2016) Mariem Ben Said et al.   HUMAN GENETICS

The unique ion permeability profile of cochlear fibrocytes and its contribution to establishing their positive resting membrane potential

(2016) Takamasa Yoshida et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Molecular architecture of the stria vascularis membrane transport system, which is essential for physiological functions of the mammalian cochlea

(2015) Satoru Uetsuka et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Connexin26 (GJB2) deficiency reduces active cochlear amplification leading to late-onset hearing loss

(2015) Y. Zhu et al.   NEUROSCIENCE

KCNK5 channels mostly expressed in cochlear outer sulcus cells are indispensable for hearing

(2015) Yves Cazals et al.   Nature Communications

Pannexin1 channels dominate ATP release in the cochlea ensuring endocochlear potential and auditory receptor potential generation and hearing

(2015) Jin Chen et al.   Scientific Reports

Negatively Charged Amino Acids Near and in Transient Receptor Potential (TRP) Domain of TRPM4 Channel Are One Determinant of Its Ca2+Sensitivity

(2014) Soichiro Yamaguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in Cx30 that are linked to skin disease and non-syndromic hearing loss exhibit several distinct cellular pathologies

(2014) A. C. Berger et al.   JOURNAL OF CELL SCIENCE

Assembly of the cochlear gap junction macromolecular complex requires connexin 26

(2014) Kazusaku Kamiya et al.   JOURNAL OF CLINICAL INVESTIGATION

Spatiotemporal expression of TRPM4 in the mouse cochlea

(2014) Mayumi Sakuraba et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Integrating the active process of hair cells with cochlear function

(2014) A. J. Hudspeth   NATURE REVIEWS NEUROSCIENCE

NKCCs in the fibrocytes of the spiral ligament are silent on the unidirectional K+ transport that controls the electrochemical properties in the mammalian cochlea

(2014) Takamasa Yoshida et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The mechanism underlying maintenance of the endocochlear potential by the K+transport system in fibrocytes of the inner ear

(2013) Naoko Adachi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Contractility in Type III Cochlear Fibrocytes Is Dependent on Non-muscle Myosin II and Intercellular Gap Junctional Coupling

(2012) John J. Kelly et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Computational model of a circulation current that controls electrochemical properties in the mammalian cochlea

(2012) F. Nin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Endocochlear Potential Alters Cochlear Micromechanics

(2011) Stefan Jacob et al.   BIOPHYSICAL JOURNAL

The connexin26 S17F mouse mutant represents a model for the human hereditary keratitis-ichthyosis-deafness syndrome

(2010) M. Schutz et al.   HUMAN MOLECULAR GENETICS

Ouabain-Induced Vacuolar Formation in Marginal Cells in the Stria Vascularis Is Dependent on Perilymphatic Na+

(2010) Kasumi Higashiyama et al.   ORL-Journal for Oto-Rhino-Laryngology Head and Neck Surgery

Epilepsy, Ataxia, Sensorineural Deafness, Tubulopathy, andKCNJ10Mutations

(2009) Detlef Bockenhauer et al.   NEW ENGLAND JOURNAL OF MEDICINE

How is the highly positive endocochlear potential formed? The specific architecture of the stria vascularis and the roles of the ion-transport apparatus

(2009) Hiroshi Hibino et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance (SeSAME syndrome) caused by mutations in KCNJ10

(2009) U. I. Scholl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endocochlear potential depends on Cl− channels: mechanism underlying deafness in Bartter syndrome IV

(2008) Gesa Rickheit et al.   EMBO JOURNAL

The endocochlear potential depends on two K+ diffusion potentials and an electrical barrier in the stria vascularis of the inner ear

(2008) F. Nin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA