Pannexin1 channels dominate ATP release in the cochlea ensuring endocochlear potential and auditory receptor potential generation and hearing

Connexin26 (GJB2) deficiency reduces active cochlear amplification leading to late-onset hearing loss

(2015) Y. Zhu et al.   NEUROSCIENCE

Deafness induced by Connexin 26 (GJB2) deficiency is not determined by endocochlear potential (EP) reduction but is associated with cochlear developmental disorders

(2014) Jin Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of an inwardly rectifying K+ channel (Kir4.1) in the inner ear and hearing loss

(2014) J. Chen et al.   NEUROSCIENCE

ATP and potassium ions: a deadly combination for astrocytes

(2014) David G. Jackson et al.   Scientific Reports

Hydrostatic pressure activates ATP-sensitive K+ channels in lung epithelium by ATP release through pannexin and connexin hemichannels

(2013) Katrin Richter et al.   FASEB JOURNAL

ATP-gated ion channels mediate adaptation to elevated sound levels

(2013) G. D. Housley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spreading Depression Triggers Headache by Activating Neuronal Panx1 Channels

(2013) H. Karatas et al.   SCIENCE

Active cochlear amplification is dependent on supporting cell gap junctions

(2013) Yan Zhu et al.   Nature Communications

Promises and pitfalls of a Pannexin1 transgenic mouse line

(2013) Regina Hanstein et al.   Frontiers in Pharmacology

ATP activates P2X receptors to mediate gap junctional coupling in the cochlea

(2012) Yan Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The biochemistry and function of pannexin channels

(2012) Silvia Penuela et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Pannexin: From discovery to bedside in 11±4 years?

(2012) Gerhard Dahl et al.   BRAIN RESEARCH

Activation of neuronal P2X7 receptor–pannexin-1 mediates death of enteric neurons during colitis

(2012) Brian D Gulbransen et al.   NATURE MEDICINE

Cell degeneration is not a primary causer for Connexin26 (GJB2) deficiency associated hearing loss

(2012) Chun Liang et al.   NEUROSCIENCE LETTERS

Pannexin channels are not gap junction hemichannels

(2011) Gina E. Sosinsky et al.   Channels

The DFNB1 subtype of autosomal recessive non-syndromic hearing impairment

(2011) Francisco J. et al.   Frontiers in Bioscience-Landmark

Pannexin 3 functions as an ER Ca2+channel, hemichannel, and gap junction to promote osteoblast differentiation

(2011) Masaki Ishikawa et al.   JOURNAL OF CELL BIOLOGY

Hyposmotic stress causes ATP release and stimulates Na,K-ATPase activity in porcine lens

(2011) M. Shahidullah et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Pannexin-1 Is Required for ATP Release during Apoptosis but Not for Inflammasome Activation

(2011) Y. Qu et al.   JOURNAL OF IMMUNOLOGY

Pannexins in ischemia-induced neurodegeneration

(2011) P. Bargiotas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pannexin 1 is the conduit for low oxygen tension-induced ATP release from human erythrocytes

(2010) Meera Sridharan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Metabolic Autocrine Regulation of Neurons Involves Cooperation among Pannexin Hemichannels, Adenosine Receptors, and KATP Channels

(2010) M. Kawamura et al.   JOURNAL OF NEUROSCIENCE

Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

(2010) Faraaz B. Chekeni et al.   NATURE

ATP-mediated potassium recycling in the cochlear supporting cells

(2010) Yan Zhu et al.   Purinergic Signalling

Reduced P2x2 receptor-mediated regulation of endocochlear potential in the ageing mouse cochlea

(2010) Ravindra S. Telang et al.   Purinergic Signalling

Pannexin 1 Contributes to ATP Release in Airway Epithelia

(2009) George A. Ransford et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Pannexin 1 Channel Activates the Inflammasome in Neurons and Astrocytes

(2009) William R. Silverman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Purinergic signaling in special senses

(2009) Gary D. Housley et al.   TRENDS IN NEUROSCIENCES

Cellular characterization of Connexin26 and Connnexin30 expression in the cochlear lateral wall

(2008) Ying-Peng Liu et al.   CELL AND TISSUE RESEARCH

Identification and characterization of pannexin expression in the mammalian cochlea

(2008) Xiao-Hui Wang et al.   JOURNAL OF COMPARATIVE NEUROLOGY

ATP activates P2x receptors and requires extracellular Ca++ participation to modify outer hair cell nonlinear capacitance

(2008) Ning Yu et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The endocochlear potential depends on two K+ diffusion potentials and an electrical barrier in the stria vascularis of the inner ear

(2008) F. Nin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA